Production of economically viable bioethanol is potentially an environmentally and financially worthwhile endeavor.One major source for fermentable sugars is lignocellulose.However,lignocellulosic biomass is difficult...
supported by grants from the National Natural Science Foundation of China(31991204);Chinese Academy of Sciences(XDA24010101)。
Plant transcription factors(TFs)are key molecular components in the regulation of plant growth,development,and environmental adaptability.Generally,TFs need to form complexes with other interactors to control gene tra...
J.C.C.was supported by the National Institute of General Medical Science(NIGMS)of the National Institutes of Health(NIH)under award number 1F31GM13761601A1;J.O.S.was supported by the ACS Bridge Program and The Genentech Foundation;This work was supported by the NIGMS of the NIH under award number R01GM095970.
Non-ribosomal peptide synthetases(NRPSs)are attractive targets for biosynthetic pathway engineering due to their modular architecture and the therapeutic relevance of their products.With catalysis mediated by specific...
supported by a Shun Hing Institute of Advanced Engineering Grant(No.4720247);a General Research Fund/Early Career Scheme(No.24201919)from the Research Grants Council of Hong Kong Special Administrative Region(to LD)。
Dynamic protein-protein interactions are essential for proper cell functioning.Homointeraction events—physical interactions between the same type of proteins—represent a pivotal subset of protein-protein interaction...
support from the Pamela and Wayne Garrison Distinguished Chair in Cancer Research,the Cancer Prevention&Research Institute of Texas(Nos.RP160667 and RP180813);the National Institutes of Health(NIH)(Nos.CA210929,CA216911,and CA216437)。
Proteins are major functional units that are tightly connected to form complex and dynamic networks.These networks enable cells and organisms to operate properly and respond efficiently to environmental cues.Over the ...
National Key Research and Development Program of China(Grant No.2016YFD0400104);the Natural Science Foundation of China(Grant Nos.31800640 and 31871531).
Physicochemical properties of endosperm starches in milled rice determine its cooking and eating quality.Amylose is synthesized by granule-bound starch synthase I(GBSSI),whilst amylopectin is synthesized by the synerg...
supported by the National Key Research&Development Program of China,No.2017YFA0104702(to AJS);the National Basic Research Program of China(973 Program),No.2014CB542201(to JP)
A large number of chemokines,cytokines,other trophic factors and the extracellular matrix molecules form a favorable microenvironment for peripheral nerve regeneration.This microenvironment is one of the major factors...
supported by the National Key R&D Program of China(2016YFA0501602);a grant from the Beijing Science and Technology Commission(Z151100003915081)
Nanopores are a label-free platform with the ability to detect subtle changes in the activities of individual biomolecules under physiological conditions.Here,we comprehensively review the technological development of...
Backgrounds Common variable immunodeficiency(CVID),the most prevalent form of primary immunodeficiency(PID),is characterized by hypogammaglobulinemia and recurrent infections.Understanding protein-protein interaction(...
Fasciculation and elongation zeta/zygin(FEZ) proteins are a family of hub proteins and share many characteristics like high connectivity in interaction networks, they are involved in several cellular processes, evolve...