PROTEIN-PROTEIN

作品数:47被引量:72H指数:4
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相关领域:生物学医药卫生更多>>
相关作者:艾观华石智陈铭刘丽丽林建成更多>>
相关机构:第二军医大学第三军医大学第一附属医院中南大学中国药科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划高等学校学科创新引智计划更多>>
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Affinity-induced covalent protein-protein ligation via the SpyCatcherSpyTag interaction被引量:3
《Green Carbon》2023年第1期33-42,共10页Jacob O.Fierer Omar E.Tovar-Herrera Jonathan Y.Weinstein Amaranta Kahn Sarah Moraïs Itzhak Mizrahi Edward A.Bayer 
Production of economically viable bioethanol is potentially an environmentally and financially worthwhile endeavor.One major source for fermentable sugars is lignocellulose.However,lignocellulosic biomass is difficult...
关键词:Synthetic Biology Protein Ligation Cellulosomes COHESIN DOCKERIN Protein Engineering Cellulose Degradation 
An efficient screening system to identify protein-protein or protein-DNA interaction partners of rice transcription factors被引量:2
《Journal of Genetics and Genomics》2022年第10期979-981,共3页Qingmei Su Fang Zhang Yunping Xiao Pingping Zhang Hefei Xing Fan Chen 
supported by grants from the National Natural Science Foundation of China(31991204);Chinese Academy of Sciences(XDA24010101)。
Plant transcription factors(TFs)are key molecular components in the regulation of plant growth,development,and environmental adaptability.Generally,TFs need to form complexes with other interactors to control gene tra...
关键词:PARTNER HEADING interaction 
Protein-protein interface analysis of the non-ribosomal peptide synthetase peptidyl carrier protein and enzymatic domains被引量:2
《Synthetic and Systems Biotechnology》2022年第2期671-682,共12页Joshua C.Corpuz Javier O.Sanlley Michael D.Burkart 
J.C.C.was supported by the National Institute of General Medical Science(NIGMS)of the National Institutes of Health(NIH)under award number 1F31GM13761601A1;J.O.S.was supported by the ACS Bridge Program and The Genentech Foundation;This work was supported by the NIGMS of the NIH under award number R01GM095970.
Non-ribosomal peptide synthetases(NRPSs)are attractive targets for biosynthetic pathway engineering due to their modular architecture and the therapeutic relevance of their products.With catalysis mediated by specific...
关键词:Natural products Protein-protein interactions Non-ribosomal peptide synthetase Peptidyl carrier protein Combinatorial biosynthesis Synthetic biology 
Optogenetic activation of intracellular signaling based on light-inducible protein-protein homo-interactions被引量:1
《Neural Regeneration Research》2022年第1期25-30,共6页Peiyuan Huang Zhihao Zhao Liting Duan 
supported by a Shun Hing Institute of Advanced Engineering Grant(No.4720247);a General Research Fund/Early Career Scheme(No.24201919)from the Research Grants Council of Hong Kong Special Administrative Region(to LD)。
Dynamic protein-protein interactions are essential for proper cell functioning.Homointeraction events—physical interactions between the same type of proteins—represent a pivotal subset of protein-protein interaction...
关键词:cryptochrome 2 homo-interaction intracellular signaling LIGHT light-induced protein-protein interaction light-oxygen-voltage-sensing domain light-sensitive proteins OPTOGENETICS PHYTOCHROME signal transduction 
Mass spectrometry-based protein-protein interaction techniques and their applications in studies of DNA damage repair
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2021年第1期1-20,共20页Zhen CHEN Junjie CHEN 
support from the Pamela and Wayne Garrison Distinguished Chair in Cancer Research,the Cancer Prevention&Research Institute of Texas(Nos.RP160667 and RP180813);the National Institutes of Health(NIH)(Nos.CA210929,CA216911,and CA216437)。
Proteins are major functional units that are tightly connected to form complex and dynamic networks.These networks enable cells and organisms to operate properly and respond efficiently to environmental cues.Over the ...
关键词:Protein-protein interaction INTERACTOME PROTEOMICS Mass spectrometry DNA repair DNA damage response 
Expression Profiles and Protein Complexes of Starch Biosynthetic Enzymes from White-Core and Waxy Mutants Induced from High Amylose Indica Rice被引量:4
《Rice science》2020年第2期152-161,共10页CHEN Yaling PANG Yuehan BAO Jinsong 
National Key Research and Development Program of China(Grant No.2016YFD0400104);the Natural Science Foundation of China(Grant Nos.31800640 and 31871531).
Physicochemical properties of endosperm starches in milled rice determine its cooking and eating quality.Amylose is synthesized by granule-bound starch synthase I(GBSSI),whilst amylopectin is synthesized by the synerg...
关键词:AMYLOSE ENDOSPERM mutant INDICA RICE PROTEIN-PROTEIN interaction starch biosynthetic enzyme WAXY RICE 
Protein microarray analysis of cytokine expression changes in distal stumps after sciatic nerve transection被引量:3
《Neural Regeneration Research》2020年第3期503-511,共9页Xiao-Qing Cheng Xue-Zhen Liang Shuai Wei Xiao Ding Gong-Hai Han Ping Liu Xun Sun Qi Quan He Tang Qing Zhao Ai-Jia Shang Jiang Peng 
supported by the National Key Research&Development Program of China,No.2017YFA0104702(to AJS);the National Basic Research Program of China(973 Program),No.2014CB542201(to JP)
A large number of chemokines,cytokines,other trophic factors and the extracellular matrix molecules form a favorable microenvironment for peripheral nerve regeneration.This microenvironment is one of the major factors...
关键词:cytokines DISTAL stump gene ontology KYOTO ENCYCLOPEDIA of Genes and Genomes pathway peripheral nerve injury protein microarray PROTEIN-PROTEIN interaction network Wallerian degeneration 
The applications of nanopores in studies of proteins被引量:2
《Science Bulletin》2019年第19期1456-1467,共12页Taoli Ding Antony KChen Zuhong Lu 
supported by the National Key R&D Program of China(2016YFA0501602);a grant from the Beijing Science and Technology Commission(Z151100003915081)
Nanopores are a label-free platform with the ability to detect subtle changes in the activities of individual biomolecules under physiological conditions.Here,we comprehensively review the technological development of...
关键词:NANOPORES PROTEINS PROTEIN-PROTEIN INTERACTIONS PROTEIN-DNA INTERACTIONS 
Identificati on of can didate disease genes in patie nts with comm on variable immunodeficiency
《Quantitative Biology》2019年第3期190-201,共12页Guojun Liu Mikhail ABolkov Irina ATuzankina Irina GDanilova 
Backgrounds Common variable immunodeficiency(CVID),the most prevalent form of primary immunodeficiency(PID),is characterized by hypogammaglobulinemia and recurrent infections.Understanding protein-protein interaction(...
关键词:common VARIABLE IMMUNODEFICIENCY primary IMMUNODEFICIENCY CANDIDATE CVID genes PROTEIN-PROTEIN interactions network density biological distance 
Fasciculation and elongation zeta proteins 1 and 2: From structural flexibility to functional diversity
《World Journal of Biological Chemistry》2019年第2期28-43,共16页Mariana Bertini Teixeira Marcos Rodrigo Alborghetti J?rg Kobarg 
Fasciculation and elongation zeta/zygin(FEZ) proteins are a family of hub proteins and share many characteristics like high connectivity in interaction networks, they are involved in several cellular processes, evolve...
关键词:Hub Intrinsically DISORDERED FEZ PROTEIN-PROTEIN interaction Neuronal development RETINOIC acid signaling INTERACTOMICS 
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