AMIFOSTINE

作品数:14被引量:36H指数:4
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相关领域:医药卫生更多>>
相关作者:杨波卢学春韩国荣王根菊吴稚冰更多>>
相关机构:中国人民解放军总医院东南大学浙江省肿瘤医院上海交通大学医学院附属瑞金医院更多>>
相关期刊:《中国实验血液学杂志》《Chinese Journal of Cancer Research》《Radiation Medicine and Protection》《World Journal of Gastroenterology》更多>>
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A DNA tetrahedron-based nanosuit for efficient delivery of amifostine and multi-organ radioprotection
《Bioactive Materials》2024年第9期191-205,共15页Yuting Yang Jinlong Yang Jianwei Zhu Xingyu Chen Li Zhou Wenjuan Ma Yunfeng Lin 
supported by National Natural Science Foundation of China(82370929);Sichuan Science and Technology Program(2022NSFSC0002 and 2024NSFSC3508);Sichuan Province Youth Science and Technology Innovation Team(2022JDTD0021);Research and Develop Program,West China Hospital of Stomatology Sichuan University(RD03202302,RCDWJS2024-1);China Postdoctoral Science Foundation(GZB2023470);Sichuan Province Innovative Talent Funding Project for Postdoctoral Fellows(BX202317);The authors would like to thank Dr.Chenghui Li(Analytical&Testing Center,Sichuan University)for technical assistance in assisting with the particle size analysis.
Unnecessary exposure to ionizing radiation(IR)often causes acute and chronic oxidative damages to normal cells and organs,leading to serious physiological and even life-threatening consequences.Amifostine(AMF)is a val...
关键词:Ionizing radiation Nanosuit AMIFOSTINE Tetrahedral framework nucleic acids DNA damage Multi-organ protection Lewis lung cancer model 
Inhaled amifostine for the prevention of radiation-induced lung injury被引量:2
《Radiation Medicine and Protection》2022年第2期72-80,共9页Ting Chen Bo Zhuang Yueqi Huang Wanmei Wang Yiguang Jin 
Objective:To alleviate radiation-induced lung injury and prevent the related pneumonitis and pulmonary fibrosis by inhaled amifostine(AMI).Methods:15 Gy 60Coγ-ray irradiation was performed on the thoracic area of rat...
关键词:AMIFOSTINE INHALATION Lung injury Pulmonary fibrosis Radiation pneumonitis 
Effectiveness and safety of different amifostine regimens:Preliminary results of a phase Ⅱ multicenter randomized controlled trial被引量:1
《Chinese Journal of Cancer Research》2018年第3期307-314,共8页Hui Chang Wei Yi Xiaohui Wang Yalan Tao Xin Yang Chen Chen Wenwen Zhang Shu Zhou Songran Liu Xiaohui Li Shirong Ding Jing Li Gong Li Xunfan Shao Yimin Liu Weishu Song Yunfei Xia 
supported by the grants of the Hi-Tech Research and Development Program of China (Grant No.2006AA02Z4B4);the National Key Projects of Research and Development of China (Grant No.2016YFC0904600)
Objective:The radioprotective effects of amifostine remain uncertain in patients with nasopharyngeal carcinoma(NPC),and adverse effects and cost limit generalization of its classical everyday regimen.This phase II ...
关键词:Nasopharyngeal carcinoma AMIFOSTINE intensity-modulated radiotherapy acute toxicity 
Effect of Amifostine on Patients with Lung Cancer Treated with Radiotherapy or Concomitant Chemoradiotherapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
《国际放射医学核医学杂志》2017年第6期413-422,共10页Huanan Wang Feng Wang Yonghan Wang 
关键词:放射学 医学研究 核医学 临床分析 
Prevention of pelvic radiation disease被引量:7
《World Journal of Gastrointestinal Pharmacology and Therapeutics》2015年第1期1-9,共9页Lorenzo Fuccio Leonardo Frazzoni Alessandra Guido 
Pelvic cancers are among the most frequently diagnosed cancers worldwide. Treatment of patients requires a multidisciplinary approach that frequently includes radiotherapy. Gastrointestinal(GI) radiation-induced toxic...
关键词:Pelvic radiation DISEASE Radiotherapy Gastrointestinal toxicity AMIFOSTINE AMINOSALICYLATES Sucralfate BECLOMETHASONE dipropionate Probiotics supplementation MISOPROSTOL MESALAZINE 
Amifostine enhances the antioxidant and hepatoprotective effects of UW and HTK preservation solutions被引量:3
《World Journal of Gastroenterology》2014年第34期12292-12300,共9页Sami Akbulut Sinasi Sevmis Hamdi Karakayali Nilüfer Bayraktar Muge Unlukaplan Ergun Oksuz Atilla Dagdeviren 
AIM: To investigate whether amifostine contributes to the antioxidant and cytoprotective effects of histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) preservation solutions.
关键词:Liver Transplantation Preservation solutions Histidine-tryptophan-ketoglutarate University of Wisconsin ANTIOXIDANT AMIFOSTINE 
Acupoint Sticking at Shenque(CV 8) with Ginger-prepared Ban Xia(Rhizoma Pinelliae) for Nausea and Vomiting Induced by Amifostine被引量:1
《Journal of Acupuncture and Tuina Science》2014年第4期221-224,共4页Wang Li-na Hu Hong-yan Qiu Yi-ling Zhou Yu-hong Hong Jue 
supported by Zhejiang Provincial Hospital of Traditional Chinese Medicine
Objective: To observe the treatment effect of acupoint sticking at Shenque (CV 8) with ginger-preparedBan Xia (Rhizoma Pinelliae) on nausea and vomiting induced by Amifostine for myelodysplastic syndromes (MDS)...
关键词:Myelodysplastic Syndromes AMIFOSTINE Drug-related Side Effects andAdverse Reactions NAUSEA VOMITING Acupoint Sticking Therapy Point Shenque (CV 8) 
Cytoprotective effects of amifostine,ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats被引量:3
《World Journal of Gastroenterology》2014年第29期10158-10165,共8页Sami Akbulut Hulya Elbe Cengiz Eris Zumrut Dogan Gulten Toprak Emrah Otan Erman Erdemli Yusuf Turkoz 
AIM: To investigate the potential role of oxidative stress and the possible therapeutic effects of N-acetyl cysteine (NAC), amifostine (AMF) and ascorbic acid (ASC) in methotrexate (MTX)-induced hepatotoxicity.
关键词:METHOTREXATE AMIFOSTINE N-acetyl cysteine Ascorbic acid HEPATOTOXICITY Oxidative stress 
Amifostine配合含铂方案化疗前应用的临床观察与护理被引量:1
《临床医药实践》2009年第5期375-377,共3页尚卜凤 郑丽君 
Amifostine(又称阿米福汀、氨磷汀)目前作为一种备受关注的全新的抗癌辅助药,能选择性保护正常器官化疗、放疗的毒性攻击,而不保护肿瘤细胞,不影响化疗药的抗肿瘤效果,并可明显减少化疗相关肝、肾功能损害的发生,减轻化疗药物所...
关键词:AMIFOSTINE 临床观察 含铂方案 化疗前 护理 细胞保护剂 一过性血压降低 抗癌辅助药 
Amifostine在恶性肿瘤放疗中的应用被引量:5
《现代肿瘤医学》2009年第4期774-776,共3页夏红强 金冶宁 
放疗是治疗恶性肿瘤的主要治疗方法之一,但往往不可避免地出现骨髓抑制等不良反应。细胞保护剂阿米福汀可以对骨髓、肝、肾等起保护作用而不影响抗肿瘤疗效。皮下注射或直肠内给药可能更适合某些病人。其细胞保护作用有一定剂量依赖性...
关键词:阿米福汀 细胞保护剂 肿瘤 放疗 
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