supported by National Natural Science Foundation of China(82370929);Sichuan Science and Technology Program(2022NSFSC0002 and 2024NSFSC3508);Sichuan Province Youth Science and Technology Innovation Team(2022JDTD0021);Research and Develop Program,West China Hospital of Stomatology Sichuan University(RD03202302,RCDWJS2024-1);China Postdoctoral Science Foundation(GZB2023470);Sichuan Province Innovative Talent Funding Project for Postdoctoral Fellows(BX202317);The authors would like to thank Dr.Chenghui Li(Analytical&Testing Center,Sichuan University)for technical assistance in assisting with the particle size analysis.
Unnecessary exposure to ionizing radiation(IR)often causes acute and chronic oxidative damages to normal cells and organs,leading to serious physiological and even life-threatening consequences.Amifostine(AMF)is a val...
Objective:To alleviate radiation-induced lung injury and prevent the related pneumonitis and pulmonary fibrosis by inhaled amifostine(AMI).Methods:15 Gy 60Coγ-ray irradiation was performed on the thoracic area of rat...
supported by the grants of the Hi-Tech Research and Development Program of China (Grant No.2006AA02Z4B4);the National Key Projects of Research and Development of China (Grant No.2016YFC0904600)
Objective:The radioprotective effects of amifostine remain uncertain in patients with nasopharyngeal carcinoma(NPC),and adverse effects and cost limit generalization of its classical everyday regimen.This phase II ...
Pelvic cancers are among the most frequently diagnosed cancers worldwide. Treatment of patients requires a multidisciplinary approach that frequently includes radiotherapy. Gastrointestinal(GI) radiation-induced toxic...
AIM: To investigate whether amifostine contributes to the antioxidant and cytoprotective effects of histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) preservation solutions.
supported by Zhejiang Provincial Hospital of Traditional Chinese Medicine
Objective: To observe the treatment effect of acupoint sticking at Shenque (CV 8) with ginger-preparedBan Xia (Rhizoma Pinelliae) on nausea and vomiting induced by Amifostine for myelodysplastic syndromes (MDS)...
AIM: To investigate the potential role of oxidative stress and the possible therapeutic effects of N-acetyl cysteine (NAC), amifostine (AMF) and ascorbic acid (ASC) in methotrexate (MTX)-induced hepatotoxicity.