PRENEOPLASIA

作品数：6被引量：12H指数：2
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相关期刊：《Science Bulletin》《World Journal of Gastroenterology》《Journal of Clinical and Translational Hepatology》《Cancer Biology & Medicine》更多>>
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Hepatocellular Ballooning is Due to Highly Pronounced Glycogenosis Potentially Associated with Steatosis and Metabolic Reprogramming
《Journal of Clinical and Translational Hepatology》2024年第1期52-61,共10页Silvia Ribback Kristin Peters Mohd Yasser Jessica Prey Paula Wilhelmi Qin Su Frank Dombrowski Peter Bannasch 
funded by the Deutsche Forschungsgemeinschaft(DFG),grant numbers RI 2695/1-1 and RI 2695/1-3。
Background and Aims:Hepatocellular ballooning is a common finding in chronic liver disease,mainly characterized by rarefied cytoplasm that often contains Mallory-Denk bodies(MDB).Ballooning has mostly been attributed ...
关键词：Chronic liver disease Carbohydrate metabolism Insulin signaling PRENEOPLASIA Metabolic reprogramming 
Road of no return——loss of TP53 paves a defined evolution path from gastric preneoplasia-to-cancer被引量：1
《Cancer Biology & Medicine》2023年第12期885-890,共6页Liwei An Yi Han Shi Jiao Zhaocai Zhou 
supported by the National Key R&D Program of China(Grant Nos.2020YFA0803200 and 2017YFA0504504);the National Natural Science Foundation of China(Grant Nos.82222052 and 32070710);the Science and Technology Commission of Shanghai Municipality(Grant Nos.22QA1407300,23ZR1480400,and 23YF1432900);Talent Climbing Project from Shanghai Tenth People’s Hospital(Grant Nos.2021SYPDRC003)。
Gastric cancer(GC),the fifth-and fourth-leading causes of morbidity and mortality worldwide,still lacks effective diagnoses and treatment.Moreover,China accounts for nearly 50%of the newly diagnosed and death cases of...
关键词：STOMACH GASTRIC HOMEOSTASIS 
Deficient Rnf43 potentiates hyperactive Kras-mediated pancreatic preneoplasia initiation and malignant transformation被引量：3
《Animal Models and Experimental Medicine》2022年第1期61-71,共11页Xian Zhou Zhichao Sun Mengdi Zhang Xiaoyu Qu Shuhui Yang Lianmei Wang Yanling Jing Li Li Weiwei Deng Fangming Liu Jin Di Jie Chen Jian Wu Hongbing Zhang 
The National Natural Science Foundation of China(81872287,81730078);the Chinese Academy of Medical Sciences Initiative for Innovative Medicine(2021-1-I2M-018).
Background:Largely due to incidental detection,asymptomatic pancreatic cystic le-sions(PCLs)have become prevalent in recent years.Among them,intraductal papillary mucinous neoplasm(IPMN)infrequently advances to pancre...
关键词：intraductal papillary mucinous neoplasms KRAS pancreatic ductal adenocarcinoma RNF43 Wnt 
Cancer Prevention? Fundamental Genomic Alterations Are Present in Preneoplasia, Including Function of High Frequency Selected Mutations (HFSMs)被引量：2
《Journal of Cancer Therapy》2016年第6期416-426,共11页Kirsten H. Walen 
In a series of publications a special, tetraploid diplochromosomal division system to only two types of progeny cells (4n/4C/G1 and 2n/4C para-diploid) has been suggested to initiate preneoplasia that can lead to a ca...
关键词：DNA/Breakage/Repair Mitotic Slippage COHESIN Tetraploid System Segregation/Orderly HYPERPLASIA Dysplasia 4n-Cell-Cycles Skewed Cytoskeleton Antibody CRISPR-Caspase Therapy 
Glycogenotic hepatocellular carcinoma with glycogen-ground-glass hepatocytes: A heuristically highly relevant phenotype被引量：5
《World Journal of Gastroenterology》2012年第46期6701-6708,共8页Peter Bannasch 
Glycogenotic hepatocellular carcinoma (HCC) with glycogen-ground-glass hepatocytes has recently been described as an allegedly "novel variant" of HCC, but neither the historical background nor the heuristic relevance ...
关键词：Acquired focal hepatic glycogenosis Inborn hepatic glycogenosis Hepatic preneoplasia Hepatic neoplasia Early metabolic aberrations Progression-linked metabolic switch 
Glutathione S-Transferase Isoenzymes as Marker in Preneoplasia of Rat Chemical Hepatocarcinogenesis被引量：1
《Chinese Science Bulletin》1993年第7期602-607,共6页左瑾 方福德 丁濂 谢大英 
Project supported by the National Natural Science Foundation of China
It has been generally accepted that about 85％ of cancers are caused by chemical factors and the chemically induced carcinogenic process can be divided into two or three stages, i. e. initiation and promotion, or toge...
关键词：GST-isoenzyme chemicai HEPATOCARCINOGENESIS isoelectric focusing MARKER enzyme. 
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