GLYCOFORMS

作品数:4被引量:4H指数:1
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相关领域:医药卫生更多>>
相关作者:秦洪强刘锋于冰李元宗廖一平更多>>
相关机构:北京大学中国科学院更多>>
相关期刊:《Frontiers of Medicine》《Open Journal of Immunology》《National Science Review》《Biomedical and Environmental Sciences》更多>>
相关基金:国家重点基础研究发展计划国家自然科学基金更多>>
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Semisynthesis of homogeneous spike RBD glycoforms from SARS-CoV-2 for profiling the correlations between glycan composition and function被引量:2
《National Science Review》2024年第2期140-149,共10页Farong Ye Cheng Li Feng-Liang Liu Xinliang Liu Peng Xu Rong-Hua Luo Wenping Song Yong-Tang Zheng Tianlei Ying Biao Yu Ping Wang 
supported by the National Science Fund for Distinguished Young Scholars (22225701);National Natural Science Foundation of China (92253302, 22077080 and 31970879);Shanghai Pilot Program for Basic Research-Shanghai Jiao Tong University (21TQ1400210);National Key R&D Program of China (2021YFC2301303 and 2022YFC2303700);Special Projects of the Central Government in Guidance of Local Science and Technology Development (2021Szvup077)
Vaccines have been the primary remedy in the global fight against coronavirus disease 2019(COVID-19).The receptor-binding domain(RBD)of the spike protein,a critical viral immunogen,is affected by the heterogeneity of ...
关键词:peptide ligation GLYCOSYLATION GLYCOPROTEIN 
CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a sweet success?被引量:1
《Frontiers of Medicine》2022年第3期322-338,共17页Pooria Safarzadeh Kozani Pouya Safarzadeh Kozani Fatemeh Rahbarizadeh 
Immune-based therapies have experienced a pronounced breakthrough in the past decades as they acquired multiple US Food and Drug Administration(FDA)approvals for various indications.To date,six chimeric antigen recept...
关键词:cancer immunotherapy chimeric antigen receptor solid tumors tumor-associated antigen GLYCOSYLATION O-GLYCANS adoptive cell therapy 
Differential Effects of Alternative Glycoforms of IgG on Human Monocytes and Macrophages: Sialylated IgG Induces Novel Expression Signatures of Cell Surface Markers, Cytokines, and Chemokines
《Open Journal of Immunology》2016年第2期49-62,共14页Eric D. Bruder John O. Richards Karen M. Michel Martin Oaks 
The effector functions elicited by the fragment crystallizable (Fc) region of immunoglobulin G (IgG) antibodies are subject to variation by the presence of terminal sialic acid (Sia) residues at asparagine-297 (Asn-29...
关键词:Anti-Inflammatory IGG IVIG MONOCYTES MACROPHAGES Sialic Acid 
Establishment of a Stable PrP^(Sc) Panel from Brain Tissues of Experimental Hamsters with Scrapie Strain 263K被引量:1
《Biomedical and Environmental Sciences》2009年第2期151-156,共6页BAO-YUN ZHANG CHAN TIAN JUN HAN CHEN GAO QI SHI JIAN-MING CHEN HUI-YING JIANG WEI ZHOU AND XIAO-PING DONG 
supported by National Science and Technology Task Force Project (2006BAD06A13-2);National Basic Research Program of China (973 Program) (2007CB310505);Institution Technique R&D Grand (2008EG150300);National Natural ScienceFoundation of China (Grants 30571672, 30500018, 30771914, and 30800975)
Objective To establish a stable PrP^Sc panel from brain tissues of experimental hamsters infected with scrapie agent 263K for evaluating diagnostic techniques of human and animals' prion diseases. Methods Thirty brai...
关键词:TSE prp^Sc PANEL GLYCOFORMS Stability 
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