SINGLE-DOSE

作品数：25被引量：28H指数：3
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相关领域：医药卫生更多>>
相关作者：谢幸吕卫国更多>>
相关机构：浙江大学医学院附属妇产科医院西安电子科技大学更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》《Virologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金更多>>
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Single-dose methamphetamine administration impairs ORM retrieval in mice via excessive DA-mediated inhibition of PrL^(Glu)activity
《Acta Pharmacologica Sinica》2024年第11期2253-2266,共14页Jian-chi Ma Xiao-hang Che Xiao-na Zhu Ao-xin Ren Yue Hu Cheng-li Yang Zhong-tian Xu Yu-ting Li Chun-fu Wu Jing-yu Yang 
supported by the National Natural Science Foundation of China(82273916,JYY);the National Natural Science Foundation of China Youth Fund Project(82204373,XHC);and the Youth Scientific Research Project of the Educational Commission of Liaoning Province(JYTQN2023320,XHC).
Methamphetamine(METH),an abused psychostimulant,impairs cognition through prolonged or even single-dose exposure,but animal experiments have shown contradictory effects on memory deficits.In this study we investigated...
关键词：cognitive deficits METHAMPHETAMINE object recognition memory memory retrieval impairment prelimbic cortex D2 receptors 
Feasibility of Integrating Leprosy Post-Exposure Prophylaxis with Single-Dose Rifampicin (LPEP) into Routine Leprosy Control Program in Bukedi and Teso Regions in Uganda
《Advances in Infectious Diseases》2024年第3期563-580,共18页Rose Kengonzi Turyahabwe Stavia Lisa Gerwing-Adima Nyote Ronald Kamara Vincent Consolata Mbambara Yusuf Wanyama Buyinza Godfrey Tinyo Daniel Mulwani Elisa Namuyode Damali Aloket Francis 
Background: World Health Organization recommends the implementation of contact tracing and Leprosy Post Exposure prophylaxis (LPEP) to interrupt the chain of transmission. To accelerate the uptake of this recommendati...
关键词：LEPROSY Post Exposure Prophylaxis Single Dose Rifampicin 
Treatment of SMA type 1 infants using a single-dose AAV9-mediated gene therapy via intrathecal injection of GC101:An open-label,single-arm study被引量：2
《Chinese Medical Journal》2024年第16期1976-1978,共3页Xiuwei Ma Lu Zhuang Wenhao Ma Jun Li Xiaodong Wang Zhongqiu Li Xinyang Jiang Yongxia Wang Ying Du Yingqian Zhang Fang He Zhiming Zhu Shaopeng Du Juan Xu Ruijie Gu Yanping Zhang Shan Zhang Ting Li Xiao Yang Sheng Zhang Lina Zhu Qiuping Li Xiaoyan Dong Xiaobing Wu Zhichun Feng 
supported by the E-Town Cooperation&Development Foundation(No.YCXJ-JZ-2022-007).
Spinal muscular atrophy(SMA),a neurodegenerative disorder caused by mutations in survival motor neuron 1(SMN1)resulting in reduced expression of the survival motor neuron(SMN)protein,is inherited in an autosomal reces...
关键词：injection MORTALITY MUSCULAR 
Pharmacokinetics and Bioequivalence of Dienogest in Healthy Bangladeshi Female Volunteers: An Open-Label, Single-Dose, Randomized, Two-Way Crossover Study被引量：1
《Open Journal of Obstetrics and Gynecology》2024年第5期779-789,共11页Nusrat Mahmud Nafisa Ahamed Uttom Kumar Bhowmik Sabrina Akter Tushi Nayan Ghosh Nithon Chandra Sahana Arifa Akram Md. Alimur Reza 
Background: Dienogest is a potential treatment for pelvic pain associated with endometriosis, a condition of significant concern in gynaecology. The current study was conducted as a crossover-randomized bioequivalence...
关键词：DIENOGEST Bioequivalence Study Endometriosis Novus CRSL 
Reduced efficacy of single-dose albendazole against Ascaris lumbricoides, and Trichuris trichiura, and high reinfection rate after cure among school children in southern Ethiopia: a prospective cohort study
《Infectious Diseases of Poverty》2024年第1期95-96,共2页Tigist Dires Gebreyesus Eyasu Makonnen Tafesse Tadele Kalkidan Mekete Habtamu Gashaw Heran Gerba Eleni Aklillu 
Background Mass drug administration(MDA)program of albendazole to at-risk populations as preventive chemo-therapy is the core public health intervention to control soil-transmitted helminths(STHs).Achieving this goal ...
关键词：Soil transmitted helminths Neglected tropical diseases Preventive chemotherapy ALBENDAZOLE School age children Ethiopia 
Bioequivalence Study of Diclofenac 150 mg XR: A Single-Dose, Randomized, Open Label, 2-Period Crossover Study in Healthy Adult Volunteers
《Journal of Biosciences and Medicines》2023年第11期23-32,共10页Evelyn Pena Alfredo Inatti Xenón Serrano Martin 
Objectives: Evaluate the bioequivalence (BE) of two oral tablets formulations of diclofenac 150 mg in healthy male subjects under fasting condition. This was a phase I, randomized, open label, balanced, two period, tw...
关键词：BIOEQUIVALENCE DICLOFENAC PHARMACOKINETICS 
Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques被引量：1
《Protein & Cell》2023年第1期69-73,共5页Dali Tong Mei Zhang Yunru Yang Han Xia Haiyang Tong Huajun Zhang Weihong Zeng Muziying Liu Yan Wu Huan Ma Xue Hu Weiyong Liu Yuan Cai Yanfeng Yao Yichuan Yao Kunpeng Liu Shifang Shan Yajuan Li Ge Gao Weiwei Guo Yun Peng Shaohong Chen Juhong Rao Jiaxuan Zhao Juan Min Qingjun Zhu Yanmin Zheng Lianxin Liu Chao Shan Kai Zhong Zilong Qiu Tengchuan Jin Sandra Chiu Zhiming Yuan Tian Xue 
supported by Strategic Priority Research Program of the Chinese Academy of Sciences(XDB39000000 to T.X.);National Natural Science Foundation of China(81925009 to T.X.,81790644 to T.X.,81900855 to M.Z.,82000941 to D.T.);Jack Ma Foundation(2019-nCoV);CAS Project for Young Scientists in Basic Research(YSBR-013);Fundamental Research Funds for the Central Universities(WK5290000001 to Y.C.,WK5290000002 to Y.Y.,WK2090050048 to M.Z.,WK2070000174 to M.Z.);supported by the Anhui Provincial Natural Science Foundation(1808085MH289 to M.Z.).Joint Laboratory of Innovation in Life Sciences from the University of Science and Technology of China(USTC)and Changchun Zhuoyi Biological Co.Ltd.
Dear Editor,Coronavirus disease 2019(COVID-19)is a highly infectious respiratory disease that continues to pose a serious global public health emergency.The disease shows a high infection rate,long incubation period,a...
关键词：RESPIRATORY ACUTE 
Same-day single-dose vs large-volume split-dose regimens of polyethylene glycol for bowel preparation:A systematic review and meta-analysis
《World Journal of Clinical Cases》2022年第22期7844-7858,共15页Hui Pan Xiao-Ling Zheng Chao-Ying Fang Lan-Zai Liu Jian-Su Chen Chao Wang Yu-Dai Chen Jian-Min Huang Yu-Shen Zhou Li-Ping He 
Supported by Startup Fund for scientific research,Fujian Medical University,No. 2019QH1181
BACKGROUND Split-dose regimens(SpDs)of 4 L of polyethylene glycol(PEG)have been established as the“gold standard”for bowel preparation;however,its use is limited by the large volumes of fluids required and sleep dis...
关键词：Bowel preparation Colonoscopy Polyethylene glycol Same-day single-dose Split-dose Metaanalysis 
Immunogenicity of a recombinant VSV-Vectored SARS-CoV vaccine induced robust immunity in rhesus monkeys after single-dose immunization
《Virologica Sinica》2022年第2期248-255,共8页Dan Shan Xiaoyan Tang Renqiang Liu Dan Pan Xijun Wang Jinying Ge Zhiyuan Wen Zhigao Bu 
supported by grants from the National Key Research and Development Program of China(2017YFD0501804)。
Severe acute respiratory syndrome(SARS)is a highly contagious zoonotic disease caused by SARS coronavirus(SARS-Co V).Since its outbreak in Guangdong Province of China in 2002,SARS has caused 8096 infections and774 dea...
关键词：Severe acute respiratory syndrome coronavirus(SARS-CoV) Vesicular stomatitis virus(VSV) VACCINE IMMUNIZATION 
Pharmacokinetics,pharmacodynamics and safety of a single-dose long-acting Risperidone injection in Chinese patients with schizophrenia被引量：2
《Journal of Chinese Pharmaceutical Sciences》2021年第3期206-217,共12页Xiaojiao Li Shuxin Luan Hong Zhang Hongquan Wan Hong Chen Chengjiao Liu Chang Liu Yanhua Ding 
Foundation items:The National Major Scientific and Technological Special Project for"Significant New Drug Development"during the Twelfth Five-year Planning Period of China(Grant No.2014ZX09303303).
In the present study,we aimed to determine the pharmacokinetics(PK),pharmacodynamics(PD),adverse events(AEs),and their relationships in Chinese patients with schizophrenia after a single dose of long-acting risperidon...
关键词：Long-acting risperidone injection SINGLE-DOSE PHARMACOKINETICS LC-MS/MS Chinese schizophrenic patients 
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