METHAMPHETAMINE

作品数：63被引量：83H指数：6
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Cortical plasticity differences in substance use disorders被引量：1
《Fundamental Research》2024年第6期1351-1356,共6页Qing-Ming Liu Molly Lucas Faizan Badami Wei Wu Amit Etkin Ti-Fei Yuan 
supported by the National Natural Science Foundation of China(32241015,81822017);The Lingang Laboratory(LG-QS-202203-10);The Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(20181715);The Shanghai Municipal Commis-sion of Health(2022JC016).
Among substances,opiates and psychostimulants are responsible for the most significant public health problems,yet few studies have characterized their similarities or differences in the cortical plasticity of individu...
关键词：Cortical plasticity METHAMPHETAMINE HEROIN Transcranial magnetic stimulation with simultaneous electroencephalography Substance use disorders 
Single-dose methamphetamine administration impairs ORM retrieval in mice via excessive DA-mediated inhibition of PrL^(Glu)activity
《Acta Pharmacologica Sinica》2024年第11期2253-2266,共14页Jian-chi Ma Xiao-hang Che Xiao-na Zhu Ao-xin Ren Yue Hu Cheng-li Yang Zhong-tian Xu Yu-ting Li Chun-fu Wu Jing-yu Yang 
supported by the National Natural Science Foundation of China(82273916,JYY);the National Natural Science Foundation of China Youth Fund Project(82204373,XHC);and the Youth Scientific Research Project of the Educational Commission of Liaoning Province(JYTQN2023320,XHC).
Methamphetamine(METH),an abused psychostimulant,impairs cognition through prolonged or even single-dose exposure,but animal experiments have shown contradictory effects on memory deficits.In this study we investigated...
关键词：cognitive deficits METHAMPHETAMINE object recognition memory memory retrieval impairment prelimbic cortex D2 receptors 
The role of the microbiota-gut-brain axis in methamphetamine-induced neurotoxicity:Disruption of microbial composition and short-chain fatty acid metabolism
《Acta Pharmaceutica Sinica B》2024年第11期4832-4857,共26页Lijian Chen Kaikai Zhang Jiali Liu Xiuwen Li Yi Liu Hongsheng M Jianzheng Yang Jiahao Li Long Chen Clare Hsu Jiahao Zeng Xiaoli Xie Qi Wang 
National Natural Science Foundation of China(Grant Nos.82171877 and 82173474);Guangdong Basic and Applied Basic Research Foundation(Grant Nos.2023A1515012476 and 2021A1515012456,China);Department of Science and Technology of Guangzhou city(Grant No.202002030043,China).
Methamphetamine(METH)abuse is associated with significant neurotoxicity,high addiction potential,and behavioral abnormalities.Recent studies have identified a connection between the gut microbiota and METH-induced neu...
关键词：METHAMPHETAMINE Gut dysbiosis Behavioral disorders Wnt/β-Catenin/GSK3βsignaling pathway Fecal microbiota transplantation Short-chainfatty acid VAGOTOMY Microbiota-gut-brain axis 
3'-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome被引量：1
《Neural Regeneration Research》2024年第10期2270-2280,共11页Yize Qi Yao Zhou Jiyang Li Fangyuan Zhu Gengni Guo Can Wang Man Yu Yijie Wang Tengfei Ma Shanwu Feng Li Zhou 
supported by the National Natural Science Foundation of China,No.81971246 (to TM);Opening Foundation of Jiangsu Key Laboratory of Neurodegeneration,Nanjing Medical University,No.KF202204 (to LZ and SF)。
Methamphetamine addiction is a brain disorder characterized by persistent drug-seeking behavior, which has been linked with aberrant synaptic plasticity. An increasing body of evidence suggests that aberrant synaptic ...
关键词：3′-deoxyadenosin hippocampus long-term potentiation METHAMPHETAMINE NOD-like receptor family pyrin domain containing-3(NLRP3)inflammasome synaptic plasticity 
Brain dysfunctions and neurotoxicity induced by psychostimulants in experimental models and humans:an overview of recent findings
《Neural Regeneration Research》2024年第9期1908-1918,共11页Marcello Serra Nicola Simola Alexia E.Pollack Giulia Costa 
supported by PON AIM(PON RICERCA E INNOVAZIONE 2014-2020,-AZIONE I.2.D.D.N.407 DEL 27 FEBBRAIO 2018-“ATTRACTION AND INTERNATIONAL MOBILITY”)(to GC);Zardi-Gori Foundation(research grant 2021)(to MS);intramural funds from the University of Cagliari(to NS);Fondazione CON IL SUD and The U.S.-Italy Fulbright Commission(to AEP).
Preclinical and clinical studies indicate that psychostimulants,in addition to having abuse potential,may elicit brain dysfunctions and/or neurotoxic effects.Central toxicity induced by psychostimulants may pose serio...
关键词：3 4-methylenedioxymethamphetamine AMPHETAMINE caffeine cell cultures cocaine METHAMPHETAMINE METHYLPHENIDATE NEUROTOXICITY nicotine 
Single-cell RNA-seq Reveals the Inhibitory Effect of Methamphetamine on Liver Immunity with the Involvement of Dopamine Receptor D1
《Genomics, Proteomics & Bioinformatics》2024年第4期59-75,共17页Jin-Ting Zhou Yungang Xu Xiao-Huan Liu Cheng Cheng Jing-Na Fan Xiaoming Li Jun Yu Shengbin Li 
supported by grants from the National Natural Science Foundation of China(Grant No.81770798);the Natural Science Foundation of Shaanxi Province(Grant No.2020JQ-083).
Methamphetamine(METH)is a highly addictive psychostimulant that causes physical and psychological damage and immune system disorder,especially in the liver which contains a significant number of immune cells.Dopamine,...
关键词：Methamphetamine chronic exposure LIVER IMMUNITY Dopamine receptor D1 Single-cell RNA sequencing. 
Fulminant Hepatitis Associated with Chronic Consumption of 3,4-Methylenedioxy-Methamphetamine;Case Report
《Open Journal of Gastroenterology》2024年第5期161-166,共6页Ulises Solis Gomez Gustavo Adolfo Hernández Valdez Juan Antonio Contreras Escamilla Ivan Alejandro Medina Jimenez Jorge Morales Rojas Jocelyn Nataly Quintero Melendez Marco Antonio González Villar 
The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA), also called ecstasy, is a neurotoxin widely consumed among young people that has increased in recent years because it is a recreational drug, of whi...
关键词：Fulminant Hepatitis Acute Liver Failure METHAMPHETAMINE Severe Acute Liver Failure in a User of Drugs of Abuse HEPATOLOGY 
Modeling functional brain connections in methamphetamine and opioid abusers
《Medicine in Novel Technology and Devices》2024年第1期88-96,共9页Nasimeh Marvi Javad Haddadnia Mohammad Reza Fayyazi Bordbar 
Substance abuse has become a significant problem worldwide.The primary purpose of this study was to model the functional brain connectivity in methamphetamines(Meth)and opioids(Op)groups in comparison with the healthy...
关键词：ELECTROENCEPHALOGRAM Methamphetamines NeuCube model OPIOIDS Spiking neural networks 
Enhanced Beta2-band Oscillations Denote Auditory Hallucination in Schizophrenia Patients and a Monkey Model of Psychosis
《Neuroscience Bulletin》2024年第3期325-338,共14页Shuo Ma Tianzhen Chen Wenjun Jia Jie Liu Shihan Ding Puzhe Li Hong Gan Dapeng Zhang Shuxin Shao Mu-Ming Poo Min Zhao Bomin Sun Jian Jiang 
supported by a Shanghai Municipal Science and Technology Major Project(2021SHZDZX,E154N41011);the Lingang Lab Program(LG2021050202 and LG2021060301);the National Nature Science Foundation(82130041);the Shanghai Rising-star Cultivation Program(22YF1439200).
An electroencephalographic(EEG)signature of auditory hallucinations(AHs)is important for facilitating the diagnosis and treatment of AHs in schizophrenia.We recorded EEG from 25 schizophrenia patients with recurrent A...
关键词：SCHIZOPHRENIA Auditory hallucinations Non-human primate METHAMPHETAMINE ELECTROENCEPHALOGRAPHY 
Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression-and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner被引量：3
《Acta Pharmaceutica Sinica B》2023年第12期4801-4822,共22页Kaikai Zhang Lijian Chen Jianzheng Yang Jiali Liu Jiahao Li Yi Liu Xiuwen Li Long Chen Clare Hsu Jiahao Zeng Xiaoli Xie Qi Wang 
supported by the National Natural Science Foundation of China under Grant No.82171877;the Department of Science and Technology of Guangzhou city under Grant No.202002030043(China);the Guangdong Natural Science Foundation under Grant No.2021A1515012456(China).
Methamphetamine(Meth)abuse can cause serious mental disorders,including anxiety and depression.The gut microbiota is a crucial contributor to maintaining host mental health.Here,we aim to investigate if microbiota par...
关键词：METHAMPHETAMINE Gut microbiota Short-chain fatty acids Sigma-1 receptor Mental disorders Colonic inflammation Intestinal barrier Gut-brain axis 
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