AMPHETAMINE

作品数：25被引量：23H指数：2
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相关领域：医药卫生更多>>
相关作者：吴蔚然朱子涛王杰鹏更多>>
相关机构：中国科学院河北中医学院河北医科大学更多>>
相关期刊：《Neural Regeneration Research》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Pharmacology & Pharmacy》更多>>
相关基金：国家自然科学基金国家高技术研究发展计划广东省自然科学基金更多>>
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Brain dysfunctions and neurotoxicity induced by psychostimulants in experimental models and humans:an overview of recent findings
《Neural Regeneration Research》2024年第9期1908-1918,共11页Marcello Serra Nicola Simola Alexia E.Pollack Giulia Costa 
supported by PON AIM(PON RICERCA E INNOVAZIONE 2014-2020,-AZIONE I.2.D.D.N.407 DEL 27 FEBBRAIO 2018-“ATTRACTION AND INTERNATIONAL MOBILITY”)(to GC);Zardi-Gori Foundation(research grant 2021)(to MS);intramural funds from the University of Cagliari(to NS);Fondazione CON IL SUD and The U.S.-Italy Fulbright Commission(to AEP).
Preclinical and clinical studies indicate that psychostimulants,in addition to having abuse potential,may elicit brain dysfunctions and/or neurotoxic effects.Central toxicity induced by psychostimulants may pose serio...
关键词：3 4-methylenedioxymethamphetamine AMPHETAMINE caffeine cell cultures cocaine METHAMPHETAMINE METHYLPHENIDATE NEUROTOXICITY nicotine 
Molecular docking of amphetamine,cathine and cathinone with dihydrofolate reductase:a computational analysis of inhibition of dihydrofolate reductase by khat alkaloids
《Toxicology Communications》2022年第2期23-28,共6页Siddig Ibrahim Abdelwahab Abdullah Farasani Ahmed Jerah Manal Mohamed Elhassan Taha Anil Bidwai 
Interaction of amphetamine,cathine and cathinone with the enzyme dihydrofolate reductase was studied by molecular docking using AutoDock 4.2 as the docking software application.AutoDock 4.2 software serves as a valid ...
关键词：AMPHETAMINE cathine CATHINONE methotrexate docking AUTODOCK DHFR khat alkaloids 
Polysubstance Use and Overdose Visualized via Maps: Amphetamines and Cocaine
《Pharmacology & Pharmacy》2022年第5期140-148,共9页Robert B. Raffa Joseph V. Pergolizzi Jr. Herm Cukier 
Abuse of drug substances and resultant overdose deaths are no longer very straightforward—viz., attributable to a single chemical entity of known purity. The reality is that most overdose deaths involve polysubstance...
关键词：Polysubstance Use/Abuse Use Disorder OVERDOSE MAPS AMPHETAMINE COCAINE 
Stroke recovery enhancing therapies:lessons from recent clinical trials
《Neural Regeneration Research》2022年第4期717-720,共4页Andreas Rogalewski Wolf-Rüdiger Schäbitz 
Poststroke recovery processes include restoration or compensation of function,respectively functions initially lost or new functions acquired after an injury.Therapeutic interventions can enhance these processes and/o...
关键词：AMPHETAMINE brain chronic stroke clinical trial DOPAMINE FLUOXETINE recovery regeneration serotonin reuptake inhibitor translation 
A biophysical perspective on the unexplored mechanisms driving Parkinson’s disease by amphetamine-like stimulants
《Neural Regeneration Research》2021年第11期2213-2214,共2页Carla Ferreira Joana Couceiro Sandra Tenreiro Alexandre Quintas 
supported by Egas Moniz Cooperativa de Ensino Superior.ST was supported by Fundação para a Ciência e Tecnologia project 02/SAICT/2017/029656 and iNOVA4Health-UIDB/04462/2020;a program financially supported by Fundação para a Ciência e Tecnologia/Ministério da Educação e Ciência,Portugal,through national funds and co-funded by FEDER under the PT2020 Partnership Agreement.
Epidemiological studies have reported an increased risk of Parkinson’s disease(PD)development in amphetamine-type stimulant users during their lifetime(Garwood et al.,2006;Rumpf et al.,2017).Protein inclusions mainly...
关键词：driving INCREMENT LIFETIME 
A prospective longitudinal study shows putamen volume is associated with moderate amphetamine use and resultant cognitive impairments
《Psychoradiology》2021年第1期3-12,共10页Keith M.Kendrick Joerg Daumann Daniel Wagner Philip Koester Marc Tittgemeyer Qiang Luo Euphrosyne Gouzoulis-Mayfrank Benjamin Becker 
supported by the National Key Research and Development Program of China(grant no.2018YFA0701400);Q.L.was supported by the National Key Research and Development Program of China(grant no.2018YFC0910503);National Natural Science Foundation of China(grant no.81873909);Shanghai Municipal Science and Technology Major Project(grant no.2018SHZDZX01);Natural Science Foundation of Shanghai(grant no.20ZR1404900);the Zhangjiang Laboratory.The authors thank all volunteers for their participation in this study.The authors declare that they have no conflict of interest.
Background:Amphetamine-type stimulants(ATS)have become a critical public health issue.Animal models have indicated a clear neurotoxic potential of ATSs.In humans,chronic use has been associated with cogni-tive deficit...
关键词：AMPHETAMINES brain volume dorsal striatum MDMA PROSPECTIVE STIMULANTS 
Rapid and simple analysis of amphetamine-type illegal drugs using excitation–emission matrix fluorescence coupled with parallel factor analysis
《Forensic Sciences Research》2019年第2期179-187,共9页Buyi Xu Yi Ye Linchuan Liao 
supported by National Natural Science Foundation of China[grant number 81373239].
Nowadays,the abuse of illegal drugs has been an increasingly grim problem in the world.Excitation–emission matrix fluorescence combined with parallel factor analysis was used to make a quantitative analysis of the si...
关键词：Forensic science illegal drugs excitation–emission matrix fluorescence PARAFAC 
Potential therapeutic effects of thymoquinone on treatment of amphetamine abuse
《Asian Pacific Journal of Tropical Biomedicine》2018年第3期187-188,共2页Nurul Farah Aina Md Fauzi Nor Hidayah Abu Bakar Nasir Mohamad Khairi Che Mat Syed Hadzrullathfi Syed Omar Mohd Shahril Othman Rohayah Husain Muhamad Zaid Ismail 
supported by Uni SZA/NRGS/2013(RR057-1)grant from Malaysia Ministry of Higher Education
Dear Editor,The prevalence of drug abuse has diverted from traditional drugs such as opioid and cannabis to modern,synthetic and psychoactive drugs such as amphetamine groups,the amphetamine(AT)and methamphetamine[1]....
关键词：Potential therapeutic effects of thymoquinone on treatment of amphetamine abuse AT 
Drug Seeking Behavior of Amphetamine Addicted Sprague-Dawley Rats Is Eliminated after Nutritional Supplementation被引量：2
《Journal of Behavioral and Brain Science》2017年第12期585-597,共13页Annice Webber-Waugh Karen Thaxter Nesbeth Pauline Anderson-Johnson Ajibike Salako-Akande Helen Asemota Lauriann Young 
Aim: The effectiveness of nutritional supplementation on drug-seeking behavior of amphetamine-addicted rats during withdrawal was investigated using a biased conditioned place preference (CPP) paradigm. Method: Twenty...
关键词：AMPHETAMINE Conditioned PLACE PREFERENCE NUTRITIONAL SUPPLEMENT ADDICTION Animal Model 
Effect of Chronic DL-Amphetamine Exposure on Brain Volume, Anxiogenic, Locomotor, and Social Behaviors in Male SD Rats
《Journal of Behavioral and Brain Science》2014年第8期375-383,共9页Alison F. Kafka Daniel A. Heinz Timothy M. Flemming Paul J. Currie 
Research examining the long-term effects of drugs such as AdderallTM, a mixed DL-amphetamine, as a first-line treatment strategy for those diagnosed with attention deficit hyperactivity disorder (ADHD), is very much l...
关键词：DL-Amphetamine Brain Elevated Plus MAZE Open Field PSYCHOSTIMULANT Social Interaction 
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