CATHINONE

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Molecular docking of amphetamine,cathine and cathinone with dihydrofolate reductase:a computational analysis of inhibition of dihydrofolate reductase by khat alkaloids
《Toxicology Communications》2022年第2期23-28,共6页Siddig Ibrahim Abdelwahab Abdullah Farasani Ahmed Jerah Manal Mohamed Elhassan Taha Anil Bidwai 
Interaction of amphetamine,cathine and cathinone with the enzyme dihydrofolate reductase was studied by molecular docking using AutoDock 4.2 as the docking software application.AutoDock 4.2 software serves as a valid ...
关键词:AMPHETAMINE cathine CATHINONE methotrexate docking AUTODOCK DHFR khat alkaloids 
A case of diffuse alveolar hemorrhage following synthetic cathinone inhalation
《World Journal of Emergency Medicine》2020年第3期182-184,共3页Masakazu Nitta Taro Tamakawa Natsuo Kamimura Tadayuki Honda Hiroshi Endoh 
Dear editor,Diffuse alveolar hemorrhage(DAH)sometimes causes a life-threatening condition;thus,prompt diagnosis and treatment for DAH is crucial.However,a variety of diseases(e.g.,systemic autoimmune diseases,infectio...
关键词:ALVEOLAR DISEASES diagnosis 
Metabolic profiling of four synthetic stimulants,including the novel indanyl-cathinone 5-PPDi,after human hepatocyte incubation
《Journal of Pharmaceutical Analysis》2020年第2期147-156,共10页David Fabregat-Safont Marie Mardal Juan V.Sancho Félix Hernández Kristian Linnet María Ibánez 
financial support from the Ministerio de Economía y Competitividad Spain(Project CTQ2015-65603-P);from Universitat Jaume I(UJI-B2018-19);Ministerio de Educación,Cultura y Deporte in Spain for his predoctoral grant(FPU15/02033);financial support received for his research stay at the University of Copenhagen(EST17/00024)。
Synthetic cathinones are new psychoactive substances that represent a health risk worldwide.For most of the 130 reported compounds,information about toxicology and/or metabolism is not available,which hampers their de...
关键词:SYNTHETIC CATHINONES 5-PPDi Metabolite identification In vitro metabolism Hepatocyte INCUBATION High resolution mass spectrometry 
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