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Atrial of arbidol hydrochloride in adults with COVID-19被引量：1: 《Chinese Medical Journal》2022年第13期1531-1538,共8页Jingya Zhao Jinnong Zhang Yang Jin Zhouping Tang Ke Hu Hui Sun Mengmeng Shi Qingyuan Yang Peiyu Gu Hongrong Guo Qi Li Haiying Zhang Chenghong Li Ming Yang Nian Xiong Xuan Dong Juanjuan Xu Fan Lin Tao Wang Chao Yang Bo Huang Jingyi Zhang hi Chen Qiong He Min Zhou Jieming Qu; Shanghai Top-Priority Clinical Key Disciplines Construction Project(No.2017ZZ02014);Shanghai Key Laboratory of Emergency Prevention,Diagnosis and Treatment of Respiratory Infectious Diseases(No.20dz2261100);Cultivation Project of Shanghai Major Infectious Disease Research Base(No.20dz2210500)。; Background: To date, there is no effective medicine to treat coronavirus disease 2019 (COVID-19), and the antiviral efficacy of arbidol in the treatment for COVID-19 remained equivocal and controversial. The purpose o...; 关键词：ARBIDOL Coronavirus disease 2019(COVID-19) Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)

Prolonged SARS-CoV-2 Viral Shedding in Patients with COVID-19 was Associated with Delayed Initiation of Arbidol Treatment and Consulting Doctor Later: A Retrospective Cohort Study: 《Current Medical Science》2021年第6期1096-1104,共9页Xin-liang HE Ya-ya ZHOU Wei FU Yu-e XUE Meng-yuan LIANG Bo-han YANG Wan-li MA Qiong ZHOU Long CHEN Jian-chu ZHANG Xiao-rong WANG; supported by Fundamental Research Funds for the Central Universities(No.2020kfyXGYJ034,No.2020kfyXGYJ009).; Objective:To study data about SARS-CoV-2 virus shedding and clarify the risk factors for prolonged virus shedding.Methods:Data were retrospectively collected from adults hospitalized with laboratory-confirmed coronavi...; 关键词：SARS-CoV-2 viral shedding risk factors antiviral treatment ARBIDOL

Efficacy of arbidol in COVID-19 patients:A retrospective study被引量：3: 《World Journal of Clinical Cases》2021年第25期7350-7357,共8页Shuo Wei Sha Xu Yun-Hu Pan; To date,no treatment has proven to be absolutely effective for coronavirus disease 2019(COVID-19)patients,and further research is necessary.As a traditional antiviral drug,arbidol was widely used in Wuhan at the begin...; 关键词：COVID-19 SARS-CoV-2 ARBIDOL TREATMENT ANTIVIRAL

Pharmacokinetic interactions between the potential COVID-19 treatment drugs lopinavir/ritonavir and arbidol in rats: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2021年第7期599-602,共4页Yunzhen HU Minjuan ZUO Xiaojuan WANG Rongrong WANG Lu LI Xiaoyang LU Saiping JIANG; the National Natural Science Foundation of China(No.81703612)。; The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-Co V-2) has occasioned worldwide alarm. Globally, the number of reported confirmed cases has exceeded 84...; 关键词：DRUGS ACUTE RESPIRATORY

Clinical efficacy of low-dose emetine for patients with COVID-19:a real-world study被引量：1: 《Journal of Bio-X Research》2021年第2期53-59,共7页Song Fan Qi Zhen Cheng Chen Wenjun Wang Qibing Wu Huihui Ma Chengyuan Zhang Li Zhang Baojing Lu Huiyao Ge Liang Yong Bao Li Yafen Yu Weiwei Chen Yiwen Mao Guangbo Qu Li Su Aoli Wang Zhen Ding Haiwen Li Jin Zhang Yonglian Wang Yufeng Gao Xihai Xu Zhongming Zhu Jun Chen Long Zhang Hongqiang Liang Song Wu Meng Huang Quan Xia Ping Li Yehuan Sun Chaozhao Liang Wei Wei Qingsong Liu Liangdan Sun; the grant from the Natural Science Foundation of Anhui Province,China(No.202004a07020007).; Objective:Emetine,an isoquinoline alkaloid that is enriched at high concentrations in the lung,has shown potent in vitro activity against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).The aim of this stu...; 关键词：ARBIDOL COVID-19 EMETINE randomized controlled clinical trial real-world study

Safety of protease inhibitors and Arbidol for SARS-CoV-2 pneumonia in Zhejiang Province,China: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2020年第12期948-954,共7页Yong-zheng GUO Kai-jin XU Yong-tao LI Jia-dan FU Min XU Ling YU Ji-fang SHENG Biao ZHU; Project supported by the National Science and Technology Major Project of China During the 13th Five-Year Plan Period(Nos.2017ZX 10202102 , 2018ZX10715014)。; 目的:评价蛋白酶抑制剂联合阿比多尔的抗病毒方案在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)肺炎患者中应用的安全性.创新点:首次评价了蛋白酶抑制剂联合阿比多尔的抗病毒方案在SARS-CoV-2肺炎患者中安全性良好.方法:回顾性分析了52例S...; 关键词：严重急性呼吸综合征冠状病毒2(SARS-CoV-2) 洛匹那韦达芦那韦肺炎血脂代谢

Efficacy and safety of the combination of Liushen capsules and Arbidol in the treatment of COVID-19:protocol for a randomized,multi-center pilot study: 《TMR Modern Herbal Medicine》2020年第4期202-208,共7页Yangqing Zhan Zhengtu Li Jiayang He Shaoqiang Li Ye Lin Jingyi Liang Jie Zhou Yanmei Wu Xuandan Su Feng Ye Zifeng Yang; This work was supported by the Science research project of the Guangdong Province[Grant No.2020B111110001];Guangzhou Medical University High-level University Clinical Research and Cultivation Program(Guangzhou Medical University released[2017]No.159,160).; Background:From early experience,some Traditional Chinese Medicine and Arbidol had effects of against COVID-19,infer that the combination of Liushen capsules and Arbidol may further increase the therapeutic.Methods/De...; 关键词：ARBIDOL Liushen capsules COVID-19 Clinical trial

Potential of Arbidol for Post-exposure Prophylaxis of COVID-19 Transmission:A Preliminary Report of a Retrospective Cohort Study被引量：11: 《Current Medical Science》2020年第3期480-485,共6页Jin-nong ZHANG Wen-jing WANG Bo PENG Wei PENG Yi-sheng ZHANG Ya-ling WANG Yan WAN Jiang CHANG Ling MAO Xiao-ping MIAO Ya-nan LI Yi-fan ZHOU Bo HU; The efficient transmission of severe acute respiratory syndrome-2 coronavirus(SARS-CoV-2)from patients to health care workers or family members has been a worrisome and prominent feature of the ongoing outbreak.On the...; 关键词：ARBIDOL COVID-19 SARS-CoV-2 post-exposure prophylaxis

Characteristics of human infection with avian influenza viruses and development of new antiviral agents被引量：8: 《Acta Pharmacologica Sinica》2013年第10期1257-1269,共13页Qiang LIU Dong-ying LIU Zhan-qiu YANG; Since 1997, several epizootic avian influenza viruses （AlVs） have been transmitted to humans, causing diseases and even deaths. The recent emergence of severe human infections with AIV （H7N9） in China has raised c...; 关键词：avian influenza human infection PATHOGENICITY antiviral agent M2 inhibitor neuraminidase inhibitor polymerase inhibitor RIBAVIRIN ARBIDOL

B, ntiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A （HIN1） virus infection被引量：18: 《Acta Pharmacologica Sinica》2013年第8期1075-1083,共9页Qiang LIU Hai-rong XIONG Li LU Yuan-yuan LIU Fan LUO Wei HOU Zhan-qiu YANG; Aim： To investigate the effects of arbidol hydrochloride （ARB）, a widely used antiviral agent, on the inflammation Jnduced by influenza virus. Methods： MDCK cells were infected with seasonal influenza A/FM/1/47 （...; 关键词：INFLUENZA antiviral agents ARBIDOL OSELTAMIVIR CYTOKINES MACROPHAGE poly I：C

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