This work was financially supported by the General Project of Zhe-jiang Provincial Department of Education[Number:Y202248699];the Science and Technology Project of Zhejiang Provincial Administra-tion of Traditional Chinese Medicine[Number:2023ZL049].
Background:The resurgence of seasonal influenza virus circulation has been seen in 2021-2022 after the tempo-rary suppression in 2020-2021.Neuraminidase inhibitors(NAIs)are widely applied in the clinical treatment of ...
This work was supported by the grants from the National Natural Science Foundation of China(31871247 and 32071443);the PublicInterest Scientific Institution Basal Research Fund(Y2019PT10,2019JB04,and Y2020XK18);the Chinese Academy of Agricultural Sciences Grants(CAAS-Y2019YJ07-03).
Influenza is a significant public health challenge because of the emergence of antigenically shifted or highly virulent strains.The neuraminidase inhibitor oseltamivir is used as an antiviral drug in clinical treatmen...
This work was supported by the National Administration of Traditional Chinese Medicine Project(2019XZZX-LG04);Chinese Academy of Traditional Chinese Medicine Project(ZZ13-035-02)to S.L.
Objective This study aimed to assess the efficacy and safety of traditional Chinese medicine,alone or in combination with oseltamivir,in patients with H1N1 Influenza.Methods In the present study,we searched the Cochra...
Natural Science Foundation of China(Grant No.81773583);Tackling Key Research Project for New Corona Virus Prevention and Treatment of Tianjin University of Science&Technology(Grant No.2020STCV0019)。
In the present study,we developed a novel colorimetric strategy for the visible rapid detection of the influenza virus based on the unique optical properties of gold nanorods.Specifically,lipoic acid-modified Oseltami...
The author acknowledges the help and support of Dr.Sabah J.Saleh(The National Center for Quality Control and Research,Ministry of Health(Iraq))and Ameer H.Khadem(Department of Pharmaceutical Chemistry,College of Pharmacy,Al-Bayan University).
Background:The emergence of Coronavirus SARS-CoV-2 evoked an unprecedented threat globally.Ever since the spread of this pandemic research and clinical trials have concentrated on the repurposing of already exciting F...
supported by the Taishan Scholars Program of Shandong Province(tsqn202103196);Shandong Medical and Health Technology Development Project(2018WS006);the Key Research and Development Project ZiBo City(2018kj060040,2016kj060025).
Severe pneumonia in patients infected with the 2009 pandemic H1N1(pH1N1)virus was partially attributed to excessive immune response.Anti-virus treatment for these patients was insufficient.Here we reported the therapy...
supported by the Fundamental Research Funds for the Central Universities (2632017PT03);the National Natural Science Foundation (No. 81700756)。
Honeysuckle has been used in the treatment of influenza virus infection for thousands of years in China.However,its main active components and the functional mechanisms remain to be elucidated.Here,four honeysuckle ex...
Influenza B(IFB)virus belongs to the Orthomyxoviridae family and has two antigenically and genetically distinct lineages;B/Victoria/2/87-like(Victoria lineage)and B/Yamagata/16/88-like(Yamagata lineage).The illness ca...
This research focused on the modification of the functional groups of oseltamivir as neuraminidase inhibitor against influenza A virus subtype H1N1.Interactions of three of the best ligands were evaluated in the hydra...