CROSS-PRESENTATION

作品数：17被引量：52H指数：3
导出分析报告
相关领域：医药卫生更多>>
相关作者：任淑萍更多>>
相关机构：浙江大学医学院附属第一医院厦门大学吉林大学更多>>
相关期刊：《Cellular & Molecular Immunology》《Infectious Diseases & Immunity》《Asian Journal of Pharmaceutical Sciences》《Bioactive Materials》更多>>
相关基金：国家自然科学基金瑞士科学基金国家重点基础研究发展计划天津市自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Zoledronate-loaded aluminum salt nanovaccines amplify cellular immune response by enhancing cross-presentation
《Nano Research》2025年第1期559-571,共13页Chunting He Penghui He Xue Tang Shuting Bai Ming Qin Yunting Zhang Zhaofei Guo Guangsheng Du Xun Sun 
supported by the National Natural Science Foundation of China(Nos.82320108020 and 81925036);the National Key Research and Development Program of China(No.2023YFC2307700);111 project(No.B18035);the Fundamental Research Funds for the Central Universities。
Being a Th2 stimulator,classic aluminum salt-based adjuvants only stimulate weak cellular immune responses that are required for vaccination against intracellular viruses or cancerous cells.As a thirdgeneration bispho...
关键词：zoledronate(ZOL) mevalonate pathway antigen cross-presentation cellular immune responses 
STING-activating dendritic cell-targeted nanovaccines that evoke potent antigen cross-presentation for cancer immunotherapy被引量：1
《Bioactive Materials》2024年第12期345-365,共21页Nguyen Thi Nguyen Xuan Thien Le Woo Tak Lee Yong Taik Lim Kyung Taek Oh Eun Seong Lee Han-Gon Choi Yu Seok Youn 
supported by a National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT,No.RS-2024-00352440 and No.NRF-2019R1A5A2027340).
Recently,nanovaccine-based immunotherapy has been robustly investigated due to its potential in governing the immune response and generating long-term protective immunity.However,the presentation of a tumor peptide-ma...
关键词：DC-based nanovaccines Artificial antigen-presenting cells Type 1 conventional dendritic cells STING pathway activation Antigen cross-presentation 
Simultaneous enhancement of cellular and humoral immunity by the lymph node-targeted cholesterolized TLR7 agonist liposomes
《Acta Pharmaceutica Sinica B》2024年第10期4577-4590,共14页Dandan Wan Ziyi Bai Yu Zhang Li Chen Haiying Que Tianxia Lan Weiqi Hong Jiayu Huang Cai He Yuquan Wei Qiang Pu Xiawei Wei 
supported by the National Science Foundation for Excellent Young Scholars(32122052,China);National Natural Science Foundation Regional Innovation and Development(No.U19A2003,China).
Toll-like receptor(TLR)agonists,as promising adjuvants and immunotherapeutic agents,have the potential to enhance immune responses and modulate antigen-dependent T-cell immune memory through activation of distinct sig...
关键词：TLR7 agonist Cationic liposomes Lymph node Cancer nanovaccines IMMUNOTHERAPY CROSS-PRESENTATION Cellular immunity Humoral immunity 
A scaffold vaccine to promote tumor antigen cross-presentation via sustained toll-like receptor-2(TLR2)activation
《Bioactive Materials》2024年第7期315-330,共16页Daping Xie Congwei Han Chonghao Chen Zhencheng Liao Senio Campos de Souza Yiming Niu Joao F.Mano Lei Dong Chunming Wang 
supported by the Science and Technology Development Fund,Macao SAR (FDCT,No.0001/2021/AKP,0024/2023/AFJ,0060/2020/AGJ,and 005/2023/SKL);the National Natural Science Foundation of China (NSFC,No.31961160701,32022088,31971309,32001069,32230056,and 32000936);the Natural Science Foundation of Jiangsu Province (BK20200318);the University of Macao (MYRG-GRG2023-00136-ICMS-UMDF and MYRG2022-00100-ICMS);support from the project CICECO-Aveiro Institute of Materials,UIDB/50011/2020,UIDP/50011/2020&LA/P/0006/2020,financed by national funds through the FCT/MEC (PIDDAC).
Cancer vaccination holds great promise for cancer treatment,but its effectiveness is hindered by suboptimal activation of CD8+cytotoxic T lymphocytes,which are potent effectors to mediate anti-tumor immune responses.A...
关键词：Scaffold vaccine TLR2 agonist POLYSACCHARIDE Reactive oxygen species CROSS-PRESENTATION 
An antigen self-assembled and dendritic cell-targeted nanovaccine for enhanced immunity against cancer被引量：2
《Acta Pharmaceutica Sinica B》2023年第8期3518-3534,共17页Yunting Zhang Min Jiangy Guangsheng Du Xiaofang Zhong Chunting He Ming Qin Yingying Hou Rong Liu Xun Sun 
financially supported by the National Natural Science Foundation of China(81925036&81872814);the Key Research and Development Program of Science and Technology Department of Sichuan Province(2020YFS0570,China);Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System(CARS-SVDIP);111 project(b18035,China);the Fundamental Research Funds for the Central Universities(China)。
The rise of nanotechnology has opened new horizons for cancer immunotherapy.However,most nano vaccines fabricated with nanomaterials suffer from carrier-related concerns,including low drug loading capacity,unpredictab...
关键词：Subunit antigen Self-assembled nanovaccine Dendritic cell Mannose receptor Zoledronic acid Antigen cross-presentation Cellular immunity Cancer immunotherapy 
Advanced subunit vaccine delivery technologies: From vaccine cascade obstacles to design strategies被引量：2
《Acta Pharmaceutica Sinica B》2023年第8期3321-3338,共18页Yingying Hou Min Chen Yuan Bian Xi Zheng Rongsheng Tong Xun Sun 
supported by the Key Research and Development Program of Science and Technology Department of Sichuan Province(No.2019YFS0514);Young Talents Project of Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital(No.2022QN08)。
Designing and manufacturing safe and effective vaccines is a crucial challenge for human health worldwide.Research on adjuvant-based subunit vaccines is increasingly being explored to meet clinical needs.Nevertheless,...
关键词：Subunitvaccine Vaccinedesign Lymph nodetargeting Dendriticcell subset targeting B cell modulation Antigencross-presentation T cell activation Antigenreleasekinetics 
A rationally designed cancer vaccine based on NIR-II fluorescence image-guided light-triggered remote control of antigen cross-presentation and autophagy被引量：1
《Acta Pharmaceutica Sinica B》2023年第7期3121-3136,共16页Aihua Wu Afeng Yang Qinli Tong Guoguang Wei Sihang Zhang Sheng Yu Chen Zhang Jiaojiao Xu Wei Lu 
supported in part by grants from National Natural Science Foundation of China(No.81991493,China);Shanghai Municipal Health Commission(No.2022XD045,China)。
Cancer vaccines represent a promising immunotherapeutic treatment modality.The promotion of cross-presentation of extracellular tumor-associated antigens on the major histocompatibility complex(MHC) class I molecules ...
关键词：Vaccine Light-triggered NIR-II imaging CROSS-PRESENTATION AUTOPHAGY SIMVASTATIN Endolysosomal escape Dendritic cell maturation 
MHC Class I Assembly Function and Intracellular Transport Routes for Hepatitis B Virus Antigen Cross-presentation by Heat Shock Protein gp96
《Infectious Diseases & Immunity》2022年第3期183-192,共10页Lijuan Qin Yongai Liu Yuxiu Xu Yang Li Jun Hu Ying Ju Yu Zhang Shuo Wang Zihai Li Changfei Li Xin Li Songdong Meng 
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB29040000);the Industrial innovation team grant from Foshan Industrial Technology Research Institute,Chinese Academy of Sciences,and the National Natural Science Foundation of China(32070163,81761128002,81871297).
Background:During hepatitis B virus(HBV)infection,virus-infected hepatocytes directly cross-present viral antigens and regulate T cell response within the liver microenvironment.However,little is known regarding the r...
关键词：Hepatitis B virus Antigen cross-presentation Cytotoxic T-cell GP96 
Dual-responsive nanovaccine for cytosolic delivery of antigens to boost cellular immune responses and cancer immunotherapy被引量：3
《Asian Journal of Pharmaceutical Sciences》2022年第4期583-595,共13页Yang Sui Ji Li Jiqiang Qu Ting Fang Hongyan Zhang Jian Zhang Zheran Wang Mingyu Xia Yinghui Dai Dongkai Wang 
Cancer vaccine contributing to the success of the treatment and prevention of tumors has attracted a huge attention as a strategy for tumor immunotherapy in recent years.A major challenge of cancer vaccine is to targe...
关键词：REDUCIBLE Nanoparticles Vaccine CROSS-PRESENTATION Immunotherapy Immune checkpoint blockade 
Trinity immune enhancing nanoparticles for boosting antitumor immune responses of immunogenic chemotherapy被引量：2
《Nano Research》2022年第2期1183-1192,共10页Yudi Xu Sheng Ma Jiayu Zhao Xinghui Si Zichao Huang Yu Zhang Wantong Song Zhaohui Tang Xuesi Chen 
supported by the National Natural Science Foundation of China(Nos.51973215,52025035,52003268,51829302,and 51833010);Bureau of International Cooperation Chinese Academy of Sciences(No.121522KYSB20200029);the Jilin Province Science and Technology Development Plan(No.2020122331JC);support from the Youth Innovation Promotion Association of Chinese Academy of Sciences(No.2020232).
Certain chemo drugs have been reported to potentially induce tumor-specific immune recognition by triggering immunogenic cell death(ICD),which provides a promising alternative way for cancer immunotherapy.However,the ...
关键词：NANOPARTICLES immunotherapy antigen capturing CROSS-PRESENTATION immune activation 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部