CINOBUFACINI

作品数：6被引量：21H指数：3
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相关领域：医药卫生更多>>
相关作者：董志勇邱仙土蔡继业更多>>
相关机构：莆田学院附属医院迪肯大学美国西北大学中国人民解放军联勤保障部队第九八八医院更多>>
相关期刊：《Chinese Herbal Medicines》《Chinese Journal of Integrative Medicine》《World Journal of Gastroenterology》《Chemical Research in Chinese Universities》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Material basis revelation of anti-hepatoma effect of Huachansu(Cinobufacini)through down-regulation of thymidylate synthase
《Chinese Herbal Medicines》2025年第1期127-138,共12页Qi Wu Qimei Chen Jingyi Yang Jiayu Zhang Ailin Yang 
financially supported by National Natural Science Foundation of China Grant(No.82204693);Taishan scholar engineering youth expert program of Shandong Province(No.tsqn202103110);Young and Creative Team for Talent Introduction of Shandong Province(No.10073004);Binzhou Medical University Scientific Research Fund for High-level Talents(NO.BY2020KYQD13,2019KYQD06);Standard study on Chinese medicinal materials and Decoction pieces in Shandong Province(No.2020-201)。
Objective:Hepatocellular carcinoma(HCC)is a leading cause of mortality worldwide.Huachansu(Cinobufacini)is active extract isolated from the dry skin of Bufo Bufo gargarizans.It has now been widely used in clinical tre...
关键词：DNA damage hepatocellular carcinoma Huachansu(Cinobufacini) material basis thymidylate synthase proteasomal degradation 
Chemical Composition, Pharmacological Effects and Clinical Applications of Cinobufacini
《Chinese Journal of Integrative Medicine》2024年第4期366-378,共13页ZUO Qian XU Ding-qiao YUE Shi-jun FU Rui-jia TANG Yu-ping 
Supported by the National Natural Science Foundation of China(No.82274084);Inheritance and Innovation of Traditional Chinese Medicine and Key Scientific Research Project of"Qin Medicine"Development of Shaanxi Administration of Traditional Chinese Medicine(No.2021-02-22-007);Subject Innovation Team of Shaanxi University of Chinese Medicine(No.2019-YL10)。
Chinese medicine cinobufacini is an extract from the dried skin of Bufo bufo gargarizans Cantor,with active ingredients of bufadienolides and indole alkaloids.With further research and clinical applications,it is foun...
关键词：CINOBUFACINI chemical composition Chinese medicine pharmacological effect clinical application adverse effect 
Cinobufacini injection for moderate and advanced primary liver cancer: A systematic review and meta-analysis被引量：8
《Journal of Chinese Pharmaceutical Sciences》2019年第4期264-275,共12页董志勇 邱仙土 Stacy A.Kujawa S.M.Shariful Islam 张杰 
Science and Technology Project of Putian University,China(Grant No.2013035)
Cinobufacini, a compound extracted from bufo toad, is a traditional Chinese medicine(TCM) that has been shown to have efficacy in cancer treatment.The cinobufacini injection is widely used in patients with moderate an...
关键词：CINOBUFACINI injection Liver cancer META-ANALYSIS Chinese HERB MEDICINE Alternative THERAPIES 
Antiproliferative effects of cinobufacini on human hepatocellular carcinoma HepG2 cells detected by atomic force microscopy被引量：12
《World Journal of Gastroenterology》2015年第3期854-861,共8页Qing Wu Wei-Dong Lin Guan-Qun Liao Li-Guo Zhang Shun-Qian Wen Jia-Ying Lin 
AIM:To investigate the antiproliferative activity of cinobufacini on human hepatocellular carcinoma HepG2 cells and the possible mechanism of its action.METHODS:HepG2 cells were treated with different concentrations o...
关键词：CINOBUFACINI CELL VIABILITY ATOMIC FORCE microscop 
Apoptosis of T-47D Cells Induced by Cinobufacini via a Caspase-3-dependent Manner被引量：3
《Chemical Research in Chinese Universities》2014年第1期108-113,共6页WANG Weiqi SHI Aiping FAN Zhimin 
Supported by the National Natural Science Foundation of China（No.30300336）.
To investigate the mechanism of the anti-tumor activity of cinobufacini on the breast cancer cell line T-47D,the inhibitory effect of cinobufacini on the proliferation of T-47D was detected via MTT assay and the morph...
关键词：Breast cancer cell CINOBUFACINI APOPTOSIS CASPASE-3 
Cinobufacini-induced HeLa cell apoptosis enhanced by curcumin被引量：1
《Chinese Science Bulletin》2013年第21期2584-2593,共10页LIU Li JIN Hua OU JinLai JIANG JinHuan PI Jiang KE ChangHong YANG Fen QIAO DongJuan CAI HuaiHong CAI JiYe 
supported by the National Basic Research Program of China (2010CB833603);Overseas, Hong Kong & Macao Cooperative Research Funds of China (31129002);the National Natural Science Foundation of China (30872404);Jinan University’s Scientific Research Cultivation and Innovation Fund (21612601)
When used in combination with certain chemotherapies, curcumin has been shown to increase apoptosis in several cancer cell lines. Here, we report the combined effects of curcumin and cinobufacini on human cervical car...
关键词：HELA细胞 细胞凋亡 姜黄素 诱导 原子力显微镜 超微结构变化 蟾 联合治疗 
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