UP-REGULATION

作品数:166被引量:662H指数:12
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相关作者:郑世曦蒋建新朱佩芳杨清武王正国更多>>
相关机构:中国科学院华中科技大学海南医学院附属医院第三军医大学大坪医院更多>>
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Down-regulation of microRNA-23a promotes pancreatic ductal adenocarcinoma initiation and progression by up-regulation of FOXM1 expression
《Genes & Diseases》2024年第5期456-469,共14页Lixin Liang Tian Cai Xiaojia Li Jianhong An Sen Yu Yang Zhang Fengjie Guo Fang Wei Jie He Keping Xie Tingting Jiang 
Guangzhou Ruiqian Biotech Company(China)(No.20230330 to TJ);the National Natural Science Foundation of China(No.82072632);Guangzhou Municipality Bureau of Science and Technology,Guangzhou,China(No.202102010033);the Natural Science Foundation of Guangdong Province,China(No.2022A1515012585 to KX).
Transcriptional factor Forkhead box M1(FOXM1)plays an important role in pancreatic ductal adenocarcinoma(PDAC)development and progression.The molecular mechanisms underlying its dysregulation remain unclear.We identif...
关键词:FOXM1 Gene expression Gene regulation MICRORNA Pancreatic cancer Targeted therapy 
Homeostatic relevance of vitamin D in maintaining male fertility in human: Down-regulation of oxidative stress and up-regulation of anti-oxidative defense and steroidal hormones
《Asian pacific Journal of Reproduction》2018年第2期56-61,共6页Fahad Hussain Arif Malik Muhammad Saeed Qureshi Muhammad Imran Sulayman Waquar Hassan Shafique Zohaib Rana Hnin Ei Thu Zahid Hussain 
Objective:To evaluate correlation between the levels of vitamin D and male infertility as well as to determine the efficacy of vitamin D in improving the male fertility by up-regulating the levels of testosterone and ...
关键词:Vitamin D Male fertility Luteinizing HORMONE Follicle-stimulating HORMONE TESTOSTERONE Oxidative stress SPERMATOGENESIS 
Meta-analysis reveals up-regulation of cholesterol processes in non-alcoholic and down-regulation in alcoholic fatty liver disease被引量:8
《World Journal of Hepatology》2017年第8期443-454,共12页Wasco Wruck James Adjaye 
Supported by The Medical Faculty of the Heinrich Heine University Düsseldorf
AIM To compare transcriptomes of non-alcoholic fatty liver disease(NAFLD) and alcoholic liver disease(ALD) in a meta-analysis of liver biopsies.METHODS Employing transcriptome data from patient liver biopsies retrieve...
关键词:Non-alcoholic fatty liver disease Alcoholic liver disease cholesterol BILE Alcohol dehydrogenase CYP7A1 
Differential Expression of miRNAs in Sorghum bicolor under Drought and Salt Stress
《American Journal of Plant Sciences》2016年第6期870-878,共9页Rania S. El Sanousi Nada B. Hamza Awadalla A. Abdelmula Ismail A. Mohammed Seif M. Gasim Neeti Sanan-Mishra 
The regulatory mechanisms of drought and salt-associated miRNAs have not been fully understood in Sorghum bicolor. In this study, we investigated the effect of salinity stress (200 and 300 mM NaCl) and drought stress ...
关键词:miRNA UP-REGULATION DOWN-REGULATION PRE-FLOWERING POST-FLOWERING 
Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin被引量:6
《Acta Biochimica et Biophysica Sinica》2014年第10期877-884,共8页Linbo Wang Yang Zeng Ye Liu Xuansheng Hu Shuhong Li Yuepeng Wang Ling Li Zhongfang Lei Zhenya Zhang 
Fucoxanthin, a natural carotenoid, has been reported to have anti-cancer activity in human colon cancer cells, human prostate cancer cells, human leukemia cells, and human epithelial cervical cancer cells. This study ...
关键词:FUCOXANTHIN human bladder cancer T24 cells Go/G1 phase mortalin p53 
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