TREATMENT-RESISTANT

作品数:9被引量:16H指数:3
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Fourth-generation chimeric antigen receptor T-cell therapy is tolerable and efficacious in treatment-resistant rheumatoid arthritis
《Cell Research》2025年第3期220-223,共4页Yujing Li Sujun Li Xiaojuan Zhao Jun Sheng Lei Xue Georg Schett Ce Shi Biliang Hu Xingbing Wang Zhu Chen 
supported by the National Natural Science Foundation of China(82471819 and 81871227 to Z.C.);Anhui Provincial Health Research Foundation(AHWJ2023A10120 to Z.C.);Anhui Provincial Natural Science Foundation(2408085J046 to Z.C.);Anhui Provincial Key Research and Development Plan(2022h11020009 to Z.C.);the Fundamental Research Funds for the Central Universities(YD9110002012 to Z.C.).
Dear Editor,Rheumatoid arthritis(RA)is an autoimmune inflammatory disease characterized by symmetric synovial inflammation leading to progressive disability.1 Treatment of RA has been revolutionized by the development...
关键词:chimeric antigen receptor autoimmune inflammatory disease fourth generation t cell therapy treatment resistant tolerable rheumatoid arthritis symmetric synovial inflammation 
Atypical Weight Loss in Two Patients with Schizophrenia Treated with Clozapine: A Case Report
《Open Journal of Applied Sciences》2024年第9期2544-2558,共15页Amel Kamal Mohammed Ghaday Saad Almutairi Abdulsalam Abdullah Almreef 
Clozapine is widely recognized as an effective antipsychotic medication for treatment-resistant schizophrenia, but it is typically associated with significant weight gain. This case report presents two unusual cases o...
关键词:SCHIZOPHRENIA CLOZAPINE Weight Loss TREATMENT-RESISTANT Atypical Antipsychotics Metabolic Effects Case Report 
Tackling heterogeneity in treatment-resistant breast cancer using a broad-spectrum therapeutic approach
《Cancer Drug Resistance》2022年第4期917-925,共9页Leroy Lowe J.William LaValley Dean W.Felsher 
Tumor heterogeneity can contribute to the development of therapeutic resistance in cancer, including advancedbreast cancers. The object of the Halifax project was to identify new treatments that would address mechanis...
关键词:Breast cancer CHEMORESISTANCE drug resistance targeted therapy 
Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer
《四川生理科学杂志》2022年第7期1206-1206,共1页Cameron Herberts 
Circulating tumour DNA(ctDNA)in blood plasma is an emerging tool for clinical cancer genotyping and longitudinal disease monitoring1.However,owing to past emphasis on targeted and low-resolution profiling approaches,o...
关键词:alterations CTDNA treatment 
Could ketamine be the answer to treating treatment-resistant major depressive disorder?被引量:1
《General Psychiatry》2020年第5期296-300,共5页Abdullah Mohammed Ramadan Islam Ahmed Mansour 
Major depressive disorder(MDD)is a common,serious,debilitating condition affecting 350 million people worldwide,which remains to be unsatisfactorily treated with 53%of patients still complaining of symptoms after comp...
关键词:KETAMINE DOSAGE SENSATION 
Clinical laboratory and imaging evidence for effectiveness of agarose-agarose macrobeads containing stem-like cells derived from a mouse renal adenocarcinoma cell population (RMBs) in treatment-resistant, advanced metastatic colorectal cancer:Evaluation of被引量:3
《Chinese Journal of Cancer Research》2018年第1期72-83,共12页Barry H.Smith Lawrence S.Gazda Thomas J.Fahey Angelica Nazarian Melissa A.Laramore Prithy Martis Zoe P.Andrada Joanne Thomas Tapan Parikh Sudipta Sureshbabu Nathaniel Berman Allyson J.Ocean Richard D.Hall David J.Wolf 
financial support of this project received from Metromedia Bio-Science, LLC
Objective: The complexity, heterogeneity and capacity of malignant neoplastic cells and tumors for rapid change and evolution suggest that living-cell-based biological-systems approaches to cancer treatment are merit...
关键词:Clinical trial systems-biology RENCA macrobeads metastatic colorectal cancer colon cancer 
Prevalence and Characteristics of Treatment-Resistant Hypertension among Hypertensive Japanese Outpatients
《International Journal of Clinical Medicine》2015年第9期623-634,共12页Keisuke Okamura Hidenori Urata 
Aims: To retrospectively investigate the prevalence and characteristics of treatment-resistant hypertension (R-HT) among consecutive hypertensive outpatients, since patients with R-HT are candidates for catheter-based...
关键词:TREATMENT-RESISTANT HYPERTENSION Catheter-Based Renal SYMPATHETIC DENERVATION Human 
Treating comorbid anxiety and depression: Psychosocial and pharmacological approaches被引量:7
《World Journal of Psychiatry》2015年第4期366-378,共13页Jeremy D Coplan Cindy J Aaronson Venkatesh Panthangi Younsuk Kim 
Comorbid anxiety with depression predicts poor outcomes with a higher percentage of treatment resistance than either disorder occurring alone. Overlap of anxiety and depression complicates diagnosis and renders treatm...
关键词:Generalized ANXIETY DISORDER Cognitive behavioral therapy TREATMENT-RESISTANT mood disorders Bipolar DISORDER COMORBID with ANXIETY Augmentation strategies Major DEPRESSIVE DISORDER 
A case report on the relationship between treatment-resistant childhood-onset schizophrenia and an abnormally enlarged cavum septum pellucidum combined with cavum vergae被引量:5
《Chinese Medical Journal》2012年第7期1349-1351,共3页LIAO Zheng-luan HU Shao-hua XU Yi 
The treatment of refractory schizophrenia has been a clinical challenge for most psychiatrists; the possible reasons include diagnostic errors, medical conditions and brain dysgenesis. Here, we described a patient wit...
关键词:SCHIZOPHRENIA septum pellucidum 
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