CLOZAPINE

作品数：37被引量：38H指数：3
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相关领域：医药卫生更多>>
相关作者：管瀚俊梁颖杰杜秀民更多>>
相关机构：首都医科大学中国科学院青岛市第二人民医院更多>>
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Atypical Weight Loss in Two Patients with Schizophrenia Treated with Clozapine: A Case Report
《Open Journal of Applied Sciences》2024年第9期2544-2558,共15页Amel Kamal Mohammed Ghaday Saad Almutairi Abdulsalam Abdullah Almreef 
Clozapine is widely recognized as an effective antipsychotic medication for treatment-resistant schizophrenia, but it is typically associated with significant weight gain. This case report presents two unusual cases o...
关键词：SCHIZOPHRENIA CLOZAPINE Weight Loss TREATMENT-RESISTANT Atypical Antipsychotics Metabolic Effects Case Report 
Multiple therapies relieve long-term tardive dyskinesia in a patient with chronic schizophrenia:A case report
《World Journal of Clinical Cases》2023年第32期7895-7899,共5页Liang Lv Ping Guo Min Feng Yu Fang Shi-Kai Wang Huan-Xin Chen 
Science and Technology Program of Huzhou City,No.2023GYB32.
BACKGROUND Tardive dyskinesia(TD)is a serious and disabling movement disorder;it impairs social function and quality of life and increases the mortality rate.TD is usually induced by the use of antipsychotic drugs;how...
关键词：Tardive dyskinesia ANTIPSYCHOTICS CLOZAPINE Deutetrabenazine Electroconvulsive therapy Case report 
Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine‑resistant treatment‑refractory schizophrenia:a 12‑week randomized,double‑blind,placebo‑controlled trial被引量：3
《Military Medical Research》2023年第4期431-443,共13页Ming‑Huan Zhu Zhen‑Jing Liu Qiong‑Yue Hu Jia‑Yu Yang Ying Jin Na Zhu Ying Huang Dian‑Hong Shi Min‑Jia Liu Hong‑Yang Tan Lei Zhao Qin‑Yu Lv Zheng‑Hui Yi Feng‑Chun Wu Ze‑Zhi Li 
supported by the National Natural Science Foundation of China(81401127);the Clinical Research Project of Shanghai Municipal Health Commission(20204Y0173);the Open Project Program of State Key Laboratory of Virtual Reality Technology and Systems,Beihang University(VRLAB2022 B02);the Shanghai Key Laboratory of Psychotic Disorders Open Grant(21-K03);the Scientific Research Project of Traditional Chinese Medicine of Guangdong(20192070);the Guangzhou Municipal Key Discipline in Medicine(2021–2023);the Science and Technology Plan Project of Guangdong Province(2019B030316001).
Background:Although clozapine is an effective option for treatment-resistant schizophrenia(TRS),there are still 1/3 to 1/2 of TRS patients who do not respond to clozapine.The main purpose of this randomized,double-bli...
关键词：Schizophrenia Clozapine-resistant treatment-refractory schizophrenia CLOZAPINE AMISULPRIDE Augmentation 
Clinical Study on Fuzi Lizhong Pill in Treating Salivation after Taking Clozapine for Schizophrenia
《Medicinal Plant》2022年第4期53-56,60,共5页Tiancheng JIA Zhe HONG Zhilian PI Chunhe MA 
Supported by Project of Science and Technology Bureau of Jiande City,Zhejiang Province(2018JYW14)。
[Objectives]To observe the clinical effect of Fuzi Lizhong pills for salivation after taking clozapine in schizophrenia.[Methods]A total of 45 cases of schizophrenia patients with salivation after taking clozapine onl...
关键词：SCHIZOPHRENIA CLOZAPINE SALIVATION Fuzi Lizhong pill TCM syndrome score Safety 
Difference between treatment-resistant schizophrenia and clozapineresistant schizophrenia
《World Journal of Psychiatry》2022年第8期1102-1104,共3页Ping-Tao Tseng Mu-Hong Chen Chih-Sung Liang 
We read the impressive review article“Clozapine resistant schizophrenia:Newer avenues of management”with great enthusiasm and appreciation.The author believes that preventing clozapine resistance from developing may...
关键词：Treatment-resistant schizophrenia CLOZAPINE Clozapine-resistant schizophrenia Ultra-resistant schizophrenia Ultra-treatment-resistant schizophrenia Superrefractory schizophrenia 
An international guideline with six personalised titration schedules for preventing myocarditis and pneumonia associated with clozapine
《General Psychiatry》2022年第3期157-162,共6页Jose de Leon Can-Jun Ruan Georgios Schoretsanitis Christopher Rohde Elif Anıl Yağcıoğlu Trino Baptista Oleg O Kirilochev Carlos De las Cuevas Christoph U Correll 
Acknowledgements Lorraine Maw at the Mental Health Research Center at Eastern State Hospital,Lexington,Kentucky,USA helped with editing.Ms.Maw declares no competing interest in the last 36 months.
White blood cell(WBC)monitoring has reduced clozapinetreated patient deaths associated with agranulocytosis to a rarity.However,clozapine protocols and package inserts worldwide provide no instructions for preventing ...
关键词：TITRATION SUBGROUPS ABSENCE 
Hyperglycemia induced by clozapine and its alternativetherapy:a case report
《Journal of Translational Neuroscience》2022年第2期18-21,共4页Lan Jiang Yuhang Liang Tiankai Jiang Yanjun Wang 
Clozapine has been recognized as the best drug for the treatment of refractory schizophrenia,but its clinical use is very cautious.Clozapine has many side effects,among which agranulocytosis is fatal.And it often caus...
关键词：SCHIZOPHRENIA CLOZAPINE glucose in-tolerance alternative therapy 
Antipsychotics preserve telomere length in peripheral blood mononuclear cells after acute oxidative stress injury
《Neural Regeneration Research》2022年第5期1156-1160,共5页Gabriel B.Polho Giancarlo M.Cardillo Daniel S.Kerr Thais Chile Wagner F.Gattaz Orestes V.Forlenza Helena P.Brentani Vanessa J.De-Paula 
supported by grants from FAPESP(Fundacao de AmparoàPesquisa de Sao Paulo,Grant no 2016/01302-9 and 2014/27129-6);CAPES(Coordenacao de Aperfeicoamento de Pessoal de Nível Superior)88887.463672/2019-00。
Antipsychotics may prolong or retain telomere length,affect mitochondrial function,and then affect the metabolism of nerve cells.To validate the hypothesis that antipsychotics can prolong telomere length after oxidati...
关键词：ANTIPSYCHOTIC ARIPIPRAZOLE cell culture CLOZAPINE HALOPERIDOL oxidative stress peripheral blood mononuclear cell telomere length 
Low-dose clozapine-related seizure: A case report and literature review被引量：1
《World Journal of Clinical Cases》2021年第20期5611-5620,共10页Dan-Sheng Le Heng Su Zheng-Luan Liao En-Yan Yu 
BACKGROUND Treatment-resistant schizophrenia is a severe form of schizophrenia characterized by poor response to at least two antipsychotic drugs and is typically treated with clozapine.However,clozapine lowers the ep...
关键词：SEIZURE Treatment-resistant schizophrenia ANTIPSYCHOTIC ANTIEPILEPTIC Electroconvulsive therapy Case report 
Clozapine resistant schizophrenia:Newer avenues of management被引量：3
《World Journal of Psychiatry》2021年第8期429-448,共20页Subho Chakrabarti 
About 40%-70%of the patients with treatment-resistant schizophrenia have a poor response to adequate treatment with clozapine.The impact of clozapineresistant schizophrenia(CRS)is even greater than that of treatment r...
关键词：Clozapine-resistance Augmentation MEDICATIONS Electroconvulsive therapy Psychosocial treatments SCHIZOPHRENIA 
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