FURANOCOUMARINS

作品数：7被引量：8H指数：1
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相关领域：医药卫生轻工技术与工程更多>>
相关作者：车镇涛王峥涛蔡金娜徐国钧更多>>
相关机构：中国药科大学香港科技大学更多>>
相关期刊：《Food and Nutrition Sciences》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Journal of Chinese Pharmaceutical Sciences》更多>>
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Furanocoumarin profiles and inhibitory effects on cytochrome P450 activity of whole citrus fruit
《Food Quality and Safety》2024年第4期684-694,共11页Yujing Sun Yihua Wang Le Zhang Xingqian Ye Jingtong Guo 
supported by the corporate-funded project(KYY-HX-20230378);the National Natural Science Foundation of China(No.31771982).
Furanocoumarins in citrus fruit can cause adverse drug interactions;however,there are few reports on furanocoumarins and drug interactions in common edible citrus cultivars except grapefruit.An ultra-performance liqui...
关键词：Citrus fruit PULP PEEL FURANOCOUMARINS cytochrome P450 
The chromosome-scale assembly of the Notopterygium incisum genome provides insight into the structural diversity of coumarins
《Acta Pharmaceutica Sinica B》2024年第8期3760-3773,共14页Qien Li Yiqun Dai Xin-Cheng Huang Lanlan Sun Kaixuan Wang Xiao Guo Dingqiao Xu Digao Wan Latai An Zixuan Wang Huanying Tang Qi Qi Huihui Zeng Minjian Qin Jia-Yu Xue Yucheng Zhao 
supported by the Western Light Project of the Chinese Academy of Sciences and the Young Qihuang Scholars Project of the National Administration of Traditional Chinese Medicine.This research was also funded by the open foundation of Shaanxi University of Chinese Medicine state key laboratory of R&D of Characteristic Qin Medicine Resources(SUCM-QM202202,China);the fund of Traditional Chinese Medicine Institute of Anhui Dabie Mountain(TCMADM-2023-18,China);“Double FirstClass”University Project of China Pharmaceutical University(CPU2022QZ27,China);supported by the key project at the central government level:the ability establishment of sustainable use for valuable Chinese medicine resources(2060302,China);the open research fund of Yunnan characteristic plant extraction laboratory(YKKF2023002,China)。
Coumarins,derived from the phenylpropanoid pathway,represent one of the primary metabolites found in angiosperms.The alignment of the tetrahydropyran(THP)and tetrahydrofuran(THF)rings with the lactone structure result...
关键词：Notopterygium incisum Parallel evolution BIOSYNTHESIS Pyranocoumarins FURANOCOUMARINS 
Two types of coumarins-specific enzymes complete the last missing steps in pyran- and furanocoumarins biosynthesis被引量：1
《Acta Pharmaceutica Sinica B》2024年第2期869-880,共12页Yucheng Zhao Yuedong He Liangliang Han Libo Zhang Yuanzheng Xia Fucheng Yin Xiaobing Wang Deqing Zhao Sheng Xu Fei Qiao Yibei Xiao Lingyi Kong 
National Key Research and Development Program of China (2018YFA0902000);the key project at central government level:the ability establishment of sustainable use for valuable Chinese medicine resources(2060302,China);the open foundation of Shaanxi University of Chinese Medicine state key laboratory of R&D of Characteristic Qin Medicine Resources (SUCM-QM202202,China);the fund of Traditional Chinese Medicine Institute of Anhui Dabie Mountain (TCMADM-2023-18,China);National Natural Science Foundation of China (32070364);Hainan Provincial Natural Science Foundation of China(2019RC309)
Pyran-and furanocoumarins are key representatives of tetrahydropyrans and tetrahydrofurans,respectively,exhibiting diverse physiological and medical bioactivities.However,the biosynthetic mechanisms for their core str...
关键词：TETRAHYDROPYRANS TETRAHYDROFURANS Baldwin rules COUMARINS CYP450cyclase 
Breeding and Analysis of Two New Grapefruit-Like Varieties with Low Furanocoumarin Content
《Food and Nutrition Sciences》2016年第2期90-101,共12页Lena Fidel Mira Carmeli-Weissberg Yosef Yaniv Felix Shaya Nir Dai Eran Raveh Yoram Eyal Ron Porat Nir Carmi 
Furanocoumarins (FCs) are a group of related plant defense metabolites occurring in several plant families, including some species in the genus citrus, such as grapefruit and pummelo. FCs function as toxins against pa...
关键词：CITRUS GRAPEFRUIT FURANOCOUMARINS BREEDING 
Solid Tumor Inhibitory and other Constituents of Casimiroa tetrameria
《中国天然药物》2011年第5期334-337,共4页XU Ya-Ming Maria del C. Ramirez-Ahumada Frederick A. Valenote A. A. Leslie Gunatilaka 
supported by the US National Institutes of Health research grant CA092143 awarded by National Cancer Institute
AIM:To isolate and characterize solid tumor inhibitory and other constituents from a bioactive extract of Casimiroa tetrameria((Rutaceae).METHODS:A crude extract of C.tetrameria obtained from the US National Cancer In...
关键词：Casimiroa tetrameria RUTACEAE Solid tumor selectivity FLAVONOIDS Zapotin FURANOCOUMARINS N-benzoyltyramides 
Inhibition of cytochrome P450 by furanocoumarins in grapefruit juice and herbal medicines被引量：7
《Acta Pharmacologica Sinica》2004年第2期129-136,共8页Lian-qingGUO YasushiYAMAZOE 
Furanocoumarins (psoralens) exist in various plants and some of them are used to cure skin diseases. Thesechemicals draw attentions recently because of their abilities to arouse drug interaction through inhibition of...
关键词：PSORALENS grapefruit juice herbal medicine enzyme inhibitors cytochrome P-450 enzyme system drug interaction 
A Novel Angular Furanocoumarin Isolated from Cnidium monnieri Fruit
《Journal of Chinese Pharmaceutical Sciences》1997年第4期15-19,共5页王峥涛 蔡金娜 徐国钧 车镇涛 
A new angular furanocoumarin, 2′ acetylangelicin (8), along with oroselone (1), columbianadin (3), bergapten (4), O acetyl columbianetin (5), cniforin A (6), edultin (7) and β sitosterol (2), was isolated fro...
关键词：Cnidium monnieri Angular furanocoumarins 2′  Acetylangelicin 
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