云南高校图书馆联盟文献共享服务平台- NEFERINE

NEFERINE: 作品数：19被引量：87H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：钱家庆徐智李青曹宏宇郭治彬更多>>; 相关机构：中南大学华中科技大学江西医学院第一附属医院南华大学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Journal of Chinese Pharmaceutical Sciences》《Acta Biochimica et Biophysica Sinica》更多>>; 相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划广东省自然科学基金更多>>

Neferine inhibits the progression of diabetic nephropathy by modulating the miR-17-5p/nuclear factor E2-related factor 2 axis被引量：3: 《Journal of Traditional Chinese Medicine》2024年第1期44-53,共10页HUANG Hongmei YANG Maojun LI Ting WANG Dandan LI Ying TANG Xiaochi YUAN Lu GU Shi XU Yong; the Chengdu Health and Wellness Commission:Exploring the Mechanism of Neferine on Diabetic Nephropathy Based on mi R-17/Nrf2 Axis(No.2021127)。; OBJECTIVE:To investigate the effect of Neferine(Nef)on diabetic nephropathy(DN)and to explore the mechanism of Nef in DN based on miRNA regulation theory.METHODS:A DN mouse model was constructed and treated with Nef.S...; 关键词：diabetic nephropathies NEFERINE miR-17-5p NF-E2-related factor 2 oxidative stress

Reversal of doxorubicin resistance in lung cancer cells by neferine is explained by nuclear factor erythroid-derived 2-like 2 mediated lung resistance protein down regulation被引量：1: 《Cancer Drug Resistance》2020年第3期647-665,共19页Poornima Paramasivan Jothi Dinesh Kumar Rathinasamy Baskaran Ching Feng Weng Viswanadha Vijaya Padma; Aim:Development of multi drug resistance and dose limiting cardiotoxicity are hindering the use of Doxorubicin(Dox)in clinical settings.Augmented dox efflux induced by lung resistance protein(LRP)over expression has b...; 关键词：DOXORUBICIN NEFERINE reactive oxygen species lung resistance protein nuclear factor erythroid-derived 2-like 2 multidrug resistance

Development of a cell-based HTS adaptable calcium fluorescent assay in FlexStation3 for the screening of TRPV3 inhibitors: 《Journal of Chinese Pharmaceutical Sciences》2017年第9期675-683,共9页Xiaomei Sun Ningning Wei Xiaoying Sun Kewei Wang; The National Natural Sciences Foundation of China(Grant No.81573410);the Ministry of Science and Technology of China(Grant No.2014ZX09507003-006-004);the Natural Sciences Foundation of Shandong Province(Grant No.ZR2015QL008); To develop a cell-based high-throughput calcium fluorescent assay for screening of TRPV3 channel modulators, we employed the FlexStation3 microplate reader and optimized conditions of the high-throughput screening （...; 关键词：TRPV3 inhibitor NEFERINE FlexStation3 Whole-cell patch clamp CALCIUM

Inhibitory Effects of Neferine on Na_v1.5 Channels Expressed in HEK293 Cells被引量：2: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第4期487-493,共7页王琛王换肖军花王嘉陵向继洲汤强; Neferine, a bisbenzylisoquinoline alkaloid in Lotus Plumule, was proved to have a wide range of biological activities. In the present study, using whole-cell patch-clamp technique, we investigated the effects of nefer...; 关键词：NEFERINE Nay1.5 channel whole-cell patch-clamp HEK293 cells

Effects of co-administraton of neferine and doxorubicin on the pharmacokinetics of doxorubicin被引量：2: 《Journal of Chinese Pharmaceutical Sciences》2015年第4期225-230,共6页薛清丹鞠爱霞康宇红郑春雨李秋红; The Scientific Research Fund Project of Heilongjiang University of Chinese Medicine(Grant No.201420); Doxorubicin is one of the anthracycline anti-neoplastic drugs widely used to treat leukemia, liver, breast, and ovarian cancers and other solid tumors. However, its clinical applications have been limited by its serio...; 关键词：Neferine Doxorubicin Pharmacokinetics HPLC method Anthracycline anti-neoplastic drugs

Synergistic Effect of Hyperthermia and Neferine on Reverse Multidrug Resistance in Adriamycin-resistant SGC7901/ADM Gastric Cancer Cells被引量：10: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2011年第4期488-496,共9页黄程辉李亚萍曹培国谢兆霞秦志强; supported by grants from Natural Science Foundation of Hunan Province(No.07JJ4009);Project of the Department of Science and Technology of Hunan Province(No. 2010FJ6029);Research and Innovation Conditions Project of Hunan Province(No.2010TT2034);125 Talent Project of the Third Xiangya Hospital of Central South University;the Freedom Explore Program of Central South University(No. 2011QNZT193),China; Multidrug resistance（MDR） plays a major obstacle to successful gastric cancer chemotherapy.The purpose of this study was to investigate the MDR reversal effect and mechanisms of hyperthermia in combination with nefe...; 关键词：gastric cancer multidrug resistance HYPERTHERMIA NEFERINE MDR-1 P-glycoprotein ADRIAMYCIN

Effects of plant extract neferine on cyclic adenosine monophosphate and cyclic guanosine monophosphate levels in rabbit corpus cavernosum in vitro被引量：6: 《Asian Journal of Andrology》2008年第2期307-312,共6页Jun Chen Ji-Hong Liu Tao Wang Heng-Jun Xiao Chun-Ping Yirl Jun Yang; Acknowledgment The authors thank Prof. Jia-Ling Wang for kindly supplying the neferine. The technical support from Prof. Bo-Hua Shu is also greatly appreciated. This study was sponsored by the National Natural Science Foundation of China （No. 30471736） and China Postdoctoral Science Foundation （No. 20070410176）.; Aim： To further investigate the relaxation mechanism of neferine （NED, a bis-benzylisoquinoline alkaloid extracted （isolated） from the green seed embryo of Nelumbo nucifera Gaertn in China, on rabbit corpus cavern...; 关键词：NEFERINE cyclic adenosine monophosphate cyclic guanosine monophosphate rabbit corpus cavernosum

Relaxation mechanisms of cavernosum tissue in vitro neferine on the rabbit corpus: 《Asian Journal of Andrology》2007年第6期795-800,共6页Jun Chen Jun Qi Fang Chen Ji-Hong Liu Tao Wang Jun Yang Chun-Ping Yin; Acknowledgment The authors thank Prof. Jia-Ling Wang for kindly supplying the Nef. The technical assistance from Mr Jun Pan （Department of Urology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China） is also greatly appreciated. This study was sponsored in part by the National Natural Science Foundation of China （No. 30471736）.; Aim： To investigate the relaxation mechanisms of neferine （Nef） on the rabbit corpus cavemosum tissue in vitro. Methods： Strips of rabbit corpus cavemosum were mounted in organ chambers. The effects of Nef were ex...; 关键词：NEFERINE corpus cavernosum RELAXATION

SENSITIVITY OF LEUKEMIC CELL LINE HL-60 TO COMBINATION OF NEFERINE AND ARSENIC: 《Chinese Journal of Cancer Research》2006年第3期183-187,共5页刘革修张洹何冬梅; This work was supported by the Grant from Natural Science Foundation of Guangdong Province (No. 04010446).; Objective： To determine whether neferine （Nef） enhances the sensitivity of human myeloid leukemia HL-60 cells to arsenic trioxide （ATO）. Methods： Apoptosis was detected by DNA electrophoresis. Giemsa staining wa...; 关键词：NEFERINE APOPTOSIS Arsenic trioxide LEUKEMIA

Multidrug resistance reversal in human gastric carcinoma cells by neferine被引量：18: 《World Journal of Gastroenterology》2004年第20期3062-3064,共3页Jian-GuoCao xiao-QingTang Shu-HongShi; AIIVI: To investigate the reversal effect of neferine on multidrug resistance in human gastric carcinoma cell line. METHODS: Cells of a human gastric cancer cells line, SGC7901, and its vincristine (VCR) -resistant va...; 关键词：多数药剂抵抗力反向作用胃癌癌细胞肿瘤荷花碱

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