相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Journal of Chinese Pharmaceutical Sciences》《Acta Biochimica et Biophysica Sinica》更多>>
Aim:Development of multi drug resistance and dose limiting cardiotoxicity are hindering the use of Doxorubicin(Dox)in clinical settings.Augmented dox efflux induced by lung resistance protein(LRP)over expression has b...
supported by grants from Natural Science Foundation of Hunan Province(No.07JJ4009);Project of the Department of Science and Technology of Hunan Province(No. 2010FJ6029);Research and Innovation Conditions Project of Hunan Province(No.2010TT2034);125 Talent Project of the Third Xiangya Hospital of Central South University;the Freedom Explore Program of Central South University(No. 2011QNZT193),China
Multidrug resistance(MDR) plays a major obstacle to successful gastric cancer chemotherapy.The purpose of this study was to investigate the MDR reversal effect and mechanisms of hyperthermia in combination with nefe...
This work was supported by the Grant from Natural Science Foundation of Guangdong Province (No. 04010446).
Objective: To determine whether neferine (Nef) enhances the sensitivity of human myeloid leukemia HL-60 cells to arsenic trioxide (ATO). Methods: Apoptosis was detected by DNA electrophoresis. Giemsa staining wa...
AIIVI: To investigate the reversal effect of neferine on multidrug resistance in human gastric carcinoma cell line. METHODS: Cells of a human gastric cancer cells line, SGC7901, and its vincristine (VCR) -resistant va...
Objective: To study the reversal effect of neferine on adriamycin (ADM) resistant human breast cancer cell line MCF-7/ADM. Methods: The cytotoxic effect of Nef or ADM was determined by 3-[4, 5-dimethylthiazol-2.-yl], ...