TETRAPLOIDY

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Epigenetic Enabled Normal Human Cells, Lead to <i>First Cell</i>’s Unique Division System, Driving Tumorigenesis Evolution
《Journal of Cancer Therapy》2022年第1期48-69,共22页Kirsten H. Walen 

Normal cells must become cancer-enabling before anything else occurs, according to latest literature. The goal in this mini-review is to demonstrate special tetraploidy...

关键词:Mitotic Slippage DNA Damage Repair Process 4-Chromatid Chromosomes Diplochromosome Tetraploidy 90°-4n Nucleus Turn G1-Phase-Diploid Cell Arrest Time Reduced Cell Cycle Fitness Increase 
Near-Dead Cells to Special Tetraploidy to First Cells to Cancer Diagnostic Morphology: Unlikely Therapy-Gain from For-Profit Industrial Goliath被引量:2
《Journal of Cancer Therapy》2020年第7期410-432,共23页Kirsten H. Walen 
The objective in this experimental article is to gain evidential proof of near-dead cells, (sick-cells in relapse tumor) responding with recovery growth from special 4n, multi-chromatid chromosomes. Note, near-dead
关键词:CYTOGENETICS Atavistic Activation 4n-Division-Perpendicularity Amalgamated Amitotic-Mitosis Loss of Function Genetics “Death” Recovery Cells Driver Mutations Tumor Parasitic Life 
Induction of gyno-tetraploidy in Japanese fl ounder Paralichthys olivaceus
《Journal of Oceanology and Limnology》2020年第1期288-293,共6页WANG Guixing ZHANG Xiaoyan SUN Zhaohui ZHAO Yaxian DU Wei CUI Jianbin HOU Jilun WANG Yufen 
Supported by the Central Public-Interest Scientific Institution Basal Research Fund,CAFS(No.2016HY-ZD0202);the China Agriculture Research System(No.CARS-47);the Applied National Science and Technology Support Program in China(No.2012BAD26B01)
Tetraploid fish are important for mass production of triploids in polyploid breeding.In this study,we reported a novel protocol for artificial induction of tetraploidy by a combination of cold shock and hydrostatic pr...
关键词:GYNOGENESIS POLYPLOIDY CHROMOSOME manipulation MOSAIC 
Mitotic Slippage Process Concealed Cancer-Sought Chromosome Instability Mechanism (S-CIN)被引量:1
《Journal of Cancer Therapy》2017年第6期608-623,共16页Kirsten H. Walen 
Official (NIH) cancer investigation is on identification of inherited cancer genes in you and me for early interventions, and for use of such knowledge in therapy. In this review the emphasis is on the unknown cancer ...
关键词:Biorhythm Microscopy Reversible Poly-Tetraploidy Fitness Increase Inherited CIN Under-Replication CANCER Genes Tumor Relapse CANCER PREDISPOSITION DNA Damage/Repair ANEUPLOID DIPLOIDY 
VACCINATION of Atlantic salmon leads to long-lasting higher levels of serum immunoglobulin and possible skewed ratios of two distinct IgM isotypes
《Advances in Bioscience and Biotechnology》2013年第4期85-90,共6页Atif Kamil Per Gunnar Fjelldal Tom Hansen Arnt Raae Erling Olaf Koppang Ivar Hordvik 
Primary and secondary antibody responses in blood of teleost fish are mainly IgM mediated, as they lack an IgG homolog and a class switch mechanism. Thus, the major serum immunoglobulin is tetrameric IgM. A unique ant...
关键词:TELEOST ATLANTIC SALMON Vaccine IGM TETRAPLOIDY 
Fen1 mutations that specifically disrupt its interaction ~vith PCNA cause aneuploidy-associated cancer被引量:3
《Cell Research》2011年第7期1052-1067,共16页Li Zheng Huifang Dai Muralidhar L Hegde Mian Zhou Zhigang Guo Xiwei Wu Jun Wu Lei Su Xueyan Zhong Sankar Mitra Qin Huang Kemp H Kernstine Gerd P Pfeifer Binghui Shen 
DNA replication and repair are critical processes for all living organisms to ensure faithful duplication and transmission of genetic information. Flap endonuclease 1 (Fenl), a structure-specific nuclease, plays an ...
关键词:FEN 1 PCNA Okazaki fragment maturation long patch base excision repair TETRAPLOIDY ANEUPLOIDY CANCER 
Establishment of an anther clone of high regenerative frequency by anther culture of homologous tetraploidy rice
《Chinese Rice Research Newsletter》1993年第1期7-8,共2页QINRuizhen SHANXueyan 
By in vitro anther culture of various generational hybrids of homologous tetraploidy rices, we established an anther clone A87203 with high regenerative frequency from the combination H3774 in 1987. It possesses tbe c...
关键词:水稻 四倍体 再生频率 花粉囊 无性系 
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