ANEUPLOID

作品数：13被引量：22H指数：3
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相关领域：医药卫生生物学更多>>
相关作者：刘继红邓秀新余振华刘元宁更多>>
相关机构：华中农业大学信息科学与技术学院中国科学技术大学更多>>
相关期刊：《Science China(Life Sciences)》《Reproductive and Developmental Medicine》《Journal of the National Cancer Center》《Marine Science Bulletin》更多>>
相关基金：国家自然科学基金International Foundation for Science广东省自然科学基金更多>>
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Disseminated tumor cells in bone marrow as predictive classifiers for small cell lung cancer patients
《Journal of the National Cancer Center》2024年第4期335-345,共11页Ying Wang Jingying Nong Baohua Lu Yuan Gao Mingming Hu Cen Chen Lina Zhang Jinjing Tan Xiaomei Yang Peter Ping Lin Xingsheng Hu Tongmei Zhang 
Beijing Municipal Science and Technol-ogy Commission(grant number Z211100002921013);Tongzhou Liang-gao Talents Project(grant number YH201920);Beijing Municipal Public Welfare Development and Reform Pilot Project for Medical Research In-stitutes(grant number JYY2024-14);Beijing Municipal Public Wel-fare Development and Reform Pilot Project for Medical Research Insti-tutes(grant number JYY2023-15);We thank all participants and their families for supporting this study.
Background: Small cell lung cancer (SCLC) is a highly aggressive disease characterized by early metastasis. Ane- uploid CD31- disseminated tumor cells (DTCs) and CD31+ disseminated tumor endothelial cells (DTECs) resi...
关键词：Bone marrow Aneuploid DTCs and DTECs SE-iFISH PROGNOSIS SCLC 
Non-invasive chromosome screening for embryo preimplantation using cell-free DNA
《Reproductive and Developmental Medicine》2022年第2期113-120,共8页Fang He Ya-Xin Yao Jing Wang Dun-Mei Zhao An-Qi Wan Jun Ren Xi Lei 
This work was supported by the Science and Technology Major Projects of Birth Defect Collaborative Prevention in Hunan Province(No.1019SK1010).
Preimplantation genetic testing (PGT) is a widely adopted screening method that can be performed to identify and select embryos with normal ploidy;however, PGT relies on embryo biopsy, that is, polar body, embryo cell...
关键词：ANEUPLOID Cell-free DNA Non-invasive preimplantation genetic testing Spent culture media 
Genotoxins exaggerate the stressed state of aneuploid embryonic stem cells via activation of autophagy
《Science China(Life Sciences)》2020年第7期1026-1036,共11页Meili Zhang Rong Xiao Guang Liu Yue Huang 
supported by the National Key Research and Development Program of China (2016YFA0100103 to Y.H.);CAMS Innovation Fund for Medical Sciences (2016-I2M-3-002 to Y.H. and M.Z.);National Natural Science Foundation of China (31701193 to M. Z.)。
The cellular consequences of aneuploidy are largely dependent on the cell types examined. Aneuploid yeasts and mouse embryonic fibroblasts exhibit cell proliferation defects and can be selectively inhibited by compoun...
关键词：ANEUPLOIDY embryonic stem cells GENOTOXINS AUTOPHAGY 
Magnitude of modulation of gene expression in aneuploid maize depends on the extent of genomic imbalance被引量：4
《Journal of Genetics and Genomics》2020年第2期93-103,共11页Adam F·Johnson Jie Hou Hua Yang Xiaowen Shi Chen Chen Md Soliman Islam Tieming Ji Jianlin Cheng James A·Birchler 
This work was supported by the National Science Foundation grants IOS-1545780,NSF 1615789,and NSF 1853556。
Aneuploidy has profound effects on an organism,typically more so than polyploidy,and the basis of this contrast is not fully understood.A dosage series of the maize long arm of chromosome 1(1L)was used to compa re rel...
关键词：ANEUPLOIDY POLYPLOIDY Inverse effect GENE regulation DOSAGE compensation GENE balance hypothesis 
Segregation Correlation of SSR Markers and Flower Traits in Aneuploid Tobacco被引量：1
《World Journal of Engineering and Technology》2018年第2期225-240,共16页Chao Liu Jiangbo Dang Lingli Wang Zhi Chen Ying Wang Guanrong Li Guolu Liang 
Few reports have been seen on the segregation of polyploids and on the relationship between the segregation of SSR loci and that of the morphological traits in polyploid progeny. This paper attempted to gain an insigh...
关键词：HEXAPLOID TOBACCO SSR Markers FLOWER Morphological TRAITS SEGREGATION Correlation 
Mitotic Slippage Process Concealed Cancer-Sought Chromosome Instability Mechanism (S-CIN)被引量：1
《Journal of Cancer Therapy》2017年第6期608-623,共16页Kirsten H. Walen 
Official (NIH) cancer investigation is on identification of inherited cancer genes in you and me for early interventions, and for use of such knowledge in therapy. In this review the emphasis is on the unknown cancer ...
关键词：Biorhythm Microscopy Reversible Poly-Tetraploidy Fitness Increase Inherited CIN Under-Replication CANCER Genes Tumor Relapse CANCER PREDISPOSITION DNA Damage/Repair ANEUPLOID DIPLOIDY 
CLImAT:Accurate detection of copy number alteration and loss of heterozygosityin impure and aneuploid tumor samples usingwhole-genome sequencingdata
《Science Foundation in China》2015年第2期19-19,共1页
With the support by the National Natural Science Foundation of China,Prof.Li Ao’s laboratory at the School of Information Science and Technology,University of Science and Technology of China,reported an algorithm to ...
关键词：ALTERATION HETEROZYGOSITY sequencing BIOINFORMATICS DELETION neutral impurity genomic hidden BIOINFORMATICS 
Colorectal cancers with aneuploids show high CD133 expression and poor prognosis
《The Chinese-German Journal of Clinical Oncology》2010年第10期601-605,共5页Dongdong Yu Yonghong Zhang You Zou Ming Tian Deding Tao Junbo Hu Jianping Gong 
Objective： The aim of the study was to investigate the relationship of DNA ploidy status in colorectal cancers with patients＇ prognosis and also the relationship of DNA ploidy status with expression of the colorecta...
关键词：colorectal cancer ANEUPLOID cancer stem cell CD133 
Improved Detection of Cervical Cancer and High Grade Neoplastic Lesions by a Combination of Conventional Cytology and DNA Automated Image Cytometer被引量：1
《Journal of Cancer Therapy》2010年第2期47-51,共5页Zuming Li Min Zhang Hua Li 
OBJECTIVE: To reduce false-negative rates of population based cervical screening programs employing conventional cytology in combination with automated DNA image cytometer. METHODS: Involved cervical samples from a to...
关键词：CERVICAL Intraepithelial NEOPLASIA (CIN) Conventional CYTOLOGY IMAGE Cytometry PLOIDY ANEUPLOID Cells Invasive CERVICAL Cancer 
Production of aneuhaploid and euhaploid sporocytes by meiotic restitution in fertile hybrids between durum wheat Langdon chromosome substitution lines and Aegilops tauschii被引量：5
《Journal of Genetics and Genomics》2008年第10期617-623,共7页Lianquan Zhang Qijiao Chen Zhongwei Yuan Zhiguo Xiang Youliang Zheng Dengcai Liu 
the National Natural Science Foundation of China (No 30700495);Education Department of Sichuan province (No 07ZZ025);Science and Technology Department of Sichuan province (No 08ZQ026-060)
Fertile F1 hybrids were obtained between durum wheat （Triticum durum Desf.） Langdon （LDN） and its 10 disomic substitution （LDN DS） lines with Aegilops tauschii accession AS60 without embryo rescue. Selfed seedse...
关键词：Aegilops tauschii ANEUPLOID durum wheat female gametes meiosis restitution unreduced gametes 
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