ALTERATION

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EWSR1-PSMC5 fusion gene variously activating autophagy in drug resistance of osteosarcoma:A novel gene fusion model report and mechanism research
《Genes & Diseases》2025年第3期7-10,共4页Qing Pan Wenbo Yang Fuhua Huang Wei Wu Zengwu Shao Zhicai Zhang 
supported by the National Natural Science Foundation of China(No.82072979).
Sarcoma is a kind of mesenchymal malignant tumor and often has poor chemotherapy response.There are many reasons for the insensitivity of sarcomas to chemotherapy,among which genetic changes are important.As a common ...
关键词：AUTOPHAGY mesenchymal malignant tumor fusion mode drug resistance ewsr psmc fusion gene gene alterationgene fusion OSTEOSARCOMA genetic changes 
Surveying Organic Matter,Thermal Maturity Level,and Paleo-Environmental Conditions by Considering Biomarker and Stable Carbon Isotopic Analysis
《Journal of Earth Science》2025年第2期428-440,共13页Meysam Hemmati Yaser Ahmadi Behzad Vaferi Ali Hosin Alibak David A.Wood 
Biomarker and stable carbon isotope analyses are presented for the Garau Formation of the Cretaceous Age,an important source rock in western Iran,to reveal its potential as an oilprone source rock.The C_(28)/C_(29)ste...
关键词：source-rock geochemistry biomarkers stable carbon isotopes alteration processes naphthenic crude oil petroleum geology 
Prevent effects of soybean meal peptides in acute alcoholic liver injury based on gut microbiota and metabolome alteration
《Food Science and Human Wellness》2025年第2期525-535,共11页Jingbo Liu Shengrao Li Qi Yang Siwen Lyu Xuanting Liu Zhiyang Du Xiaomin Shang Ting Zhang 
funded by the National Key R&D Program of China(2022YFD2101002);Jilin Province Science and Technology Youth Talent Support Project(QT202021);Fundamental Research Funds for the Central Universities。
This study investigated the preventive effects of soybean meal peptides(SPs)and their purification peptides(GTYW)on acute alcoholic liver injury.We combined the gut microbiota,metabolites,liver inflammation,and oxidat...
关键词：Soybean meal peptides Acute alcoholic liver injury Gut microbiota METABOLITES 
Comparative Study of a Lithological Description by Geoelectrical and Hydrogeological Drilling in a Basement Environment: Site of the Jean Lorougnon Guédé University in Daloa (Centre-West of the Ivory Coast)
《Open Journal of Modern Hydrology》2025年第1期18-31,共14页Assoue Kouakou Sylvestre Kouadio Assa Maxime Abbe Gountoh Aristide Douagui Oscar Zahibo Onetie Kouassi Constantin Gautier Kanga 
The comparative study of electrical and hydrogeological soundings is being carried out on the site of the Jean Lorougnon Guédé University in Daloa, in central-western Côte d’Ivoire. The aim of this study is to dete...
关键词：Electrical Soundings Hydrogeological Soundings BOREHOLES Crystalline Basement Alteration Profile Daloa 
Preliminary Report on the Paleoproterozoic Metasediments Genesis and Features of the Banfora Belt Western Burkina Faso (West Africa Craton)
《International Journal of Geosciences》2025年第1期1-19,共19页Hermann Ilboudo Bernadin Gnamou Wilfried Antoine Bassou Toe Marc Ephrem Allialy 
Metasedimentary rocks of the Banfora belt are examined for their petrography geochemistry and genesis. The main formations are pelite metapelites sandstone, and metagraywackes. The first ones show a fine interlocking ...
关键词：METASEDIMENTS Banfora Belt Source ALTERATION Geotectonic Environment 
Variants within KIF5B are associated with weight loss through mitochondrial transport alteration in sheep
《Journal of Genetics and Genomics》2024年第12期1513-1516,共4页Jieran Chen Haitao Wang Tingting Li Yuting Zhang Yan Chen Na Zhang Hengqian Yang Zhichao Zhang Ziyuan Duan Xia Li Daxiang Wang Zhixiong He Fan Hu Jianfeng Gao Runlin Z.Ma Xun Huang Qiuyue Liu 
supported by the Strategic Priority Research Program of Chinese Academy of Sciences(XDA24030205 and XDA26040303);Biological Breeding-National Science and Technology Major Project(2023ZD0407106 and 2023ZD0406805)。
Sheep(Ovis aries)is a key source of meat for humans,and their weight loss significantly impacts meat production.Although a few causative genes related to weight loss have been identified,the inheritance mechanisms and...
关键词：CHAINS WEIGHT SHEEP 
Beyond natural flow:Human-directed course change of the Kolong river in Nagaon,Assam,(India)and its socio-ecological implications
《River》2024年第4期408-415,共8页Manash Jyoti Bhuyan Nityananda Deka 
The Kolong,a significant distributary of the mighty river Brahmaputra in Assam,India,has experienced significant human-induced alterations aimed basically for flood mitigation.This study investigates the socio-ecologi...
关键词：ecological sustainability flood mitigation integrated river management river course alteration socioeconomic impacts 
Hydrothermal alteration of the surface volcanic rocks at the Acoculco geothermal field,Mexico:a multi-parametric approach
《Acta Geochimica》2024年第6期1037-1053,共17页America Yosiris García-Soto Kailasa Pandarinath ESantoyo Eduardo Gonzalez-Partida 
Rock magnetic instruments used in this work are procured with the funding from CEMIE Geo project 207032(Fondo de Sustentabilidad Energética de CONACy T-SENER,Government of Mexico)。
The studies on hydrothermal alteration-induced eff ects in surface and subsurface rocks provide useful information in the characterization and exploitation of a geothermal reservoir.Generally,these studies are based o...
关键词：Geothermal fields Hydrothermal alteration Surface rocks Magnetic susceptibility Alteration indices 
Bone loss with aging is independent of gut microbiome in mice
《Bone Research》2024年第4期980-993,共14页Xiaomeng You Jing Yan Jeremy Herzog Sabah Nobakhti Ross Campbell Allison Hoke Rasha Hammamieh R.Balfour Sartor Sandra Shefelbine Melissa A.Kacena Nabarun Chakraborty Julia F.Charles 
supported by NIH grants R01 AG046257 (JFC);the Orthopaedic Scholar Fund;the Department of Orthopaedic Surgery,Brigham and Women’s Hospital,P30 AR075042;the Joint Biology Consortium funded by P30-AR070253;performed at National Gnotobiotic Rodent Resource Center at University of North Carolina at Chapel Hill,funded by P40-OD010995,P30-DK034987;Crohn’s and Colitis Foundation;supported with resources and the use of facilities at the Richard L.Roudebush VA Medical Center,Indianapolis,IN:VA Merit#BX003751。
Emerging evidence suggests a significant role of gut microbiome in bone health.Aging is well recognized as a crucial factor influencing the gut microbiome.In this study,we investigated whether age-dependent microbial ...
关键词：METABOLISM AGING ALTERATION 
Dynamic Uncertainty:Exploring the Spatial Order of Future Digital Architecture
《Journal of Civil Engineering and Architecture》2024年第10期475-484,共10页Yuxin Zhao 
The spatial order of architecture has been significantly impacted by digital architectural design and production,creating a dynamic uncertainty.This study aims to explore digital architecture from the perspective of s...
关键词：Spatial superimposition digital technology’s antidote&poison effect the spatial order of digital architectures alteration of spatial order 
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