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作品数:910被引量:1439H指数:12
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L-Ergothioneine ameliorates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in C57BL/6J mice by activating DJ-1
《Food Science and Human Wellness》2025年第3期1045-1061,共17页Xianshe Meng Huawen Meng Shuzeng Hou Zequn Yin Xuerui Wang Ke Gong Feng Zhang Qingshan Li Shuang Zhang Yuanli Chen Xiaoxiao Yang Zhiwei Zhao Chenzhong Liao Yajun Duan 
supported by the National Natural Science Foundation of China(U22A20272,82173807,82170497)。
Parkinson's disease(PD)is one of the most common neurodegenerative diseases.The loss of dopaminergic(DAergic)neurons in the substantia nigra and the decrease of dopamine(DA)levels accelerate the process of PD.L-Ergoth...
关键词:L-Ergothioneine 1-Methyl-4-phenyl-1 2 3 6-TETRAHYDROPYRIDINE Parkinson’s disease DJ-1 Dopaminergic neurons 
[Ni(4,4′-bpy)_(2)(phen)][H_(2)SiW_(12)O_(40)]·2H_(2)O的合成、结构及光催化性能研究
《吉林师范大学学报(自然科学版)》2025年第2期32-39,共8页刘亚冰 李洪印 王梓烨 
国家自然科学基金项目(51801070)。
混合配体簇聚物不仅极大地丰富了杂化材料的结构多样性,还赋予了它们独特的性能.本文以Na_(2)WO_(4)·2H_(2)O、Na_(2)SiO_(3)、邻菲啰啉(phen)、4,4′-联吡啶(4,4′-bpy)和NiCl_(2)·6H_(2)O为原料,通过水热合成法制备了一种新型混合...
关键词:混合有机配体 簇基杂化材料 光催化 水热合成 
Rhapontin activates nuclear factor erythroid 2-related factor 2 to ameliorate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced gastrointestinal dysfunction in Parkinson's disease mice
《World Journal of Gastroenterology》2025年第15期96-108,共13页Xin-Yu Wang Fang Liu Qi-Tong Wang Shu-Zhu Li Yu-Zhao Ye Tao Chen Ben-Chi Cai 
Supported by the Hainan Provincial Natural Science Foundation of China,No.823MS133 and No.821QN0979。
BACKGROUND Parkinson's disease(PD)-a progressive neurodegenerative disorder-is characterized by motor and gastrointestinal dysfunction.The exploration of novel therapeutic strategies for PD is vital.AIM To investigate...
关键词:Rhapontin Gastrointestinal dysfunction Parkinson’s disease Nuclear factor erythroid 2-related factor 2 Gut-Brain axis Oxidative stress NEUROINFLAMMATION 
Cyanex923/TBP/PHEN协同2-噻吩甲酰三氟丙酮对Li(Ⅰ)的电膜萃取研究
《化工学报》2024年第12期4606-4616,共11页孟晓荣 孙驰 龙伊文 
国家重点研发计划项目(2022YFC2904304-01);陕西省技术创新引导专项-重点研发计划三项改革项目(2023GXLH-060)。
为强化2-噻吩甲酰三氟丙酮(HTTA)萃锂体系的性能,分别制备了以三烷基氧化膦、磷酸三丁酯、邻菲罗啉3种协萃剂配伍的聚氯乙烯基二元复合萃取膜(PT-PIMs),用于研究电场强化的膜萃取提锂技术。考察了膜相组成和操作电压对Li(Ⅰ)传质性能的...
关键词:  电膜萃取 HTTA+协萃剂 稳定性 选择性 
Phenolic-enabled nanotechnology:a new strategy for central nervous system disease therapy
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第10期890-913,共24页Yuyi ZHENG Xiaojie CHEN Yi WANG Zhong CHEN Di WU 
supported by the National Natural Science Foundation of China(No.82273861);the Young Elite Scientists Sponsorship Program by China Association for Science and Technology(CAST)(No.YESS20220139).
Polyphenolic compounds have received tremendous attention in biomedicine because of their good biocompatibility and unique physicochemical properties.In recent years,phenolic-enabled nanotechnology(PEN)has become a ho...
关键词:Phenolic-enabled nanotechnology(PEN) Metal-phenolic network POLYDOPAMINE Central nervous system(CNS) Drug delivery system 
Eu(Ibu)_(3)phen配合物的合成表征及发光性
《吉首大学学报(自然科学版)》2024年第3期88-90,共3页王莹 沈景辉 胡丽娜 马冬云 史成阳 李炳寅 
黑龙江省卫生厅项目(2019-285);黑龙江省大学生创新创业项目(2021102221)。
以药物布洛芬为第一配体,稀土离子Eu(Ⅲ)为中心离子,采用溶剂法合成了Eu^(3+)、布洛芬(Ibu)和邻菲罗啉(phen)的稀土-布洛芬药物配合物Eu(Ibu)3phen,采用元素分析、紫外光谱、红外光谱对配合物进行了初步结构表征,并研究了配合物的荧光性...
关键词:稀土配合物 EU 布洛芬 荧光性质 
Total flavonoids of Astragalus membranaceus protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice by inhibiting ferroptosis through SLC7A11/GPX-4 signaling pathway被引量:1
《Food Science and Human Wellness》2024年第1期414-420,共7页Zitian Gao Gaorui Wang Yujie Chen Wuke Yuan Jun Cai Aiping Feng Jie Fang Qi Xu Xiaojun Wu 
Parkinson’s disease(PD)is a common neurodegenerative disorder with no cure.Astragalus membranaceus is used in Chinese culture as a food supplement to boost immunity.The present study aimed to explore the neuroprotect...
关键词:Parkinson’s disease Total fl avonoids of Astragalus membranaceus Ferroptosis SLC7A11 
偶氮苯衍生物(E)-1-phenyl-2-((triisopropylsilyl)ethynyl)diazene的超快光异构动力学研究
《Chinese Journal of Chemical Physics》2023年第6期664-670,I0055,I0056,共9页林依澜 魏小凡 方栋 王子钰 黄逸凡 李涛 刘伟民 
当暴露在特定波长的光下时,偶氮苯及其衍生物会通过异构化从反式转变为顺式.由于偶氮苯在光照下发生颜色变化的能力,它在各种分子器件和功能材料中得到了广泛应用.然而,尽管有大量关注实际应用方面的研究,但对偶氮苯光化学反应和顺反异...
关键词:偶氮苯衍生物 异构化 飞秒受激拉曼 呼啦扭转 
Chloride-Bridged Dimeric SalphenZr(IV) Cobaltate Catalyst Unleashes the Potential of Base-Free Carbonylative Polymerization for Biodegradable PHAs
《Chinese Journal of Chemistry》2023年第24期3560-3566,共7页Vinothkumar Ganesan Sungho Yoon 
supported by C1 Gas Refinery Program(2018M3D3A1A01018006);Direct Air Capture and Utilization(DACU)grant(RS-2023-00259920)through the National Research Foundation of Korea funded by the Ministry of Science,ICT;Future Planning,Republic of Korea.
Poly(3-hydroxyalkanoates) (PHAs) are a promising class of biodegradable polymers,exhibiting properties comparable to traditional petroleum-based counterparts.Nonetheless,the widespread commercialization of PHAs is hin...
关键词:C1 building blocks Chloro bridged salphenZr(IV)dimer Homogeneous catalysis CARBONYLATION Carbonylative polymerization Biodegradable polymer Poly(3-hydroxyalkanoates) 
Synthesis and Characterization of 9,9-diethyl-1-phenyl-1,9-dihydrofluoreno[2,3-d]imidazole-ended Fluorophores
《Journal of Wuhan University of Technology(Materials Science)》2023年第6期1484-1488,共5页LI Saijun WANG Tianqi TAN Qitao LIN Haixia CUI Yongmei 
Funded by the Natural Science Foundation of Shanghai City(No.19ZR1419700)。
A series ofπ-conjugated compounds ending with 9,9-diethyl-1-phenyl-1,9-dihydrofluoreno[2,3-d]imidazole were conveniently synthesized by condensation of the key intermediate9,9-diethyl-N^(2)-phenyl-9H-fluorene-2,3-dia...
关键词:FLUORENE IMIDAZOLE synthesis UV absorption fluorescence 
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