SESAMIN

作品数:22被引量:44H指数:3
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相关领域:医药卫生更多>>
相关作者:周仁杰吴静雷红刘末鲁曼霞更多>>
相关机构:合肥工业大学南京财经大学韩国中央大学湖南中医药大学更多>>
相关期刊:《Oil Crop Science》《Acta Pharmacologica Sinica》《中草药》《Journal of Integrative Agriculture》更多>>
相关基金:国家自然科学基金安徽省自然科学基金湖南省自然科学基金博士科研启动基金更多>>
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Sesamin is an effective spleen tyrosine kinase inhibitor against IgE-mediated food allergy in computational,cell-based and animal studies
《Food Science and Human Wellness》2025年第2期469-483,共15页Yu Li Xuerui Chen Longhua Xu Xintong Tan Dapeng Li Dongxiao Sun-Waterhouse Feng Li 
Incubation Program of Youth Innovation in Shandong Province;Key Research and Development Program of Shandong Province(2021TZXD007)。
Food allergy has become a global concern.Spleen tyrosine kinase(SYK)inhibitors are promising therapeutics against allergic disorders.In this study,a total of 300 natural phenolic compounds were firstly subjected to vi...
关键词:Food allergy Spleen tyrosine kinase SESAMIN Computational tools RBL-2H3 cells BALB/c mice 
Mechanisms of sesamol and sesamin inhibitingα-glucosidase activity by spectroscopy and molecular docking被引量:1
《Food Bioscience》2023年第3期1641-1648,共8页Shijia Zhang Yiren Zhang Emad Karrar Qingzhe Jin Hui Zhang Gangcheng Wu Xingguo Wang 
supported by the National Key Research and Development Project of China(2021YFD2100303).
Sesamol and sesamin inhibitα-glucosidase activity and may therefore be effective in treating type 2 diabetes,but their mechanisms remain unknown.Therefore,the inhibitory effects of sesamol and sesamin onα-glucosidas...
关键词:SESAMOL SESAMIN Α-GLUCOSIDASE Inhibition mechanism SPECTROSCOPY Molecular docking 
Antioxidant lignans sesamin and sesamolin in sesame(Sesamum indicum L.):a comprehensive review and future prospects被引量:2
《Journal of Integrative Agriculture》2023年第1期14-30,共17页Senouwa Segla Koffi DOSSOU XU Fang-tao Komivi DOSSA ZHOU Rong ZHAO Ying-zhong WANG Lin-hai 
study was supported by the Open Project of Key Laboratory of Biology and Genetic Improvement of Oil Crops,Ministry of Agriculture and Rural Affairs,China(KF2020004,KF2022002);the Agricultural Science and Technology Innovation Project of the Chinese Academy of Agricultural Sciences(CAAS-ASTIP-2016-OCRI);the Key Research Projects of Hubei Province,China(2020BBA045,2020BHB028);the Science and Technology Innovation Project of Hubei Province,China(2021-620-000-001-035);the China Agriculture Research System of MOF and MARA(CARS-14);the Fundamental Research Funds for Central Non-profit Scientific Institution,China(Y2022XK11).
Sesame(Sesamum indicum L.)is a significantly lucrative cash crop for millions of small-holder farmers.Its seeds are an important source of a highly appreciated vegetable oil globally and two clinically essential antio...
关键词:Sesamum indicum lignan biosynthesis ANTIOXIDANTS molecular breeding sesamin and sesamolin 
Beneficial Regulatory Effects of Sesamin on Intestinal Flora of Mice
《Agricultural Biotechnology》2022年第6期84-88,共5页Yu DENG Mengxi WANG Xiaogeng LIU Pan LIU Hong LEI 
Support by National Natural Science Foundation of China(Grant No.31872899);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
The effects of sesamin on intestinal microflora of mice with normal diet were studied by in vitro animal feces anaerobic culture system.The results showed that treatment with sesamin could significantly change the int...
关键词:SESAMIN Intestinal flora Beneficial regulatory effect Abundance of probiotics 
Potential immunomodulatory role of sesamin in combating immune dysregulation associated with COVID-19
《Asian Pacific Journal of Tropical Biomedicine》2021年第10期421-428,共8页Amin F.Majdalawieh Sarah M.Yousef Imad A.Abu-Yousef 
The ongoing outbreak of novel coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has caused an unprecedented global health crisis.Development of a cure for this de...
关键词:SESAMIN SARS-CoV-2 COVID-19 IMMUNOMODULATION ANTI-INFLAMMATORY Cytokine storm Th1/Th2 balance 
HPLC法同时检测16种五加属植物中14种苯丙素类成分被引量:3
《中草药》2020年第14期3791-3796,共6页肖珊 罗姣 许忠 黄完均 肖瑾 鲁曼霞 卢茂芳 刘向前 
湖南省自然科学基金项目(2019JJ40223);湖南省自然科学基金项目(2019JJ50448);湖南省教育厅一般项目(18C0399);湖南中医药大学生物工程重点学科资助(校行科字[2018] 3号)。
目的建立以HPLC法同时检测16种33批五加属植物中紫丁香苷、绿原酸、咖啡酸、对香豆酸、阿魏酸、ethylsyringin、ethylconiferin、(+)-梣皮树脂醇、(±)-松脂素、(±)-丁香脂素、taiwanin C、savinin、helioxanthin、(-)-sesamin 14种苯...
关键词:五加属 苯丙素类 紫丁香苷 绿原酸 咖啡酸 对香豆酸 阿魏酸 ethylsyringin ethylconiferin (+)-梣皮树脂醇 (±)-松脂素 (±)-丁香脂素 taiwanin C savinin helioxanthin (-)-sesamin 
Impact of sesame lignan on physical and oxidative stability of flaxseed oil-in-water emulsion被引量:1
《Oil Crop Science》2019年第4期254-266,共13页Xintian Wang Kun Yu Chen Cheng Xiao Yu David Julian McClements Wenwen Huang Jia Yang Fenghong Huang Qianchun Deng 
financial support from the National Natural Science Foundation of China (31771938);the Earmarked Fund for China Agriculture Research System (CARS-14);partly based upon work supported by the National Institute of Food and Agriculture, USDA, Massachusetts Agricultural Experiment Station (MAS00491) and USDA, AFRI Grants (2016-08782)
Recent studies have shown that the highly susceptibility to oxidation ofα-linolenic acid(ALA)enriched emulsion delivery system was harmful for human health which limited their incorporation into functional food.Impac...
关键词:lipid oxidation SESAMOL SESAMIN quillaja SAPONIN OIL-IN-WATER emulsions 
Optimal Conditions for the Purification of Sesamin by Recrystallization被引量:4
《Agricultural Science & Technology》2017年第7期1202-1204,1364,共4页刘末 周仁杰 吴静 雷红 
Supported by Natural Science Foundation of Anhui Province(1608085MC53)~~
[Objective] Sesamin has been widely used in healthy food and medicines in recent years due to its prominent biological functions. This study was aimed to determine the optimal parameters for sesamin recrystallization,...
关键词:SESAMIN RECRYSTALLIZATION Orthogonal array testing HPLC 
Sesamin alleviates blood-brain barrier disruption in mice with experimental traumatic brain injury被引量:6
《Acta Pharmacologica Sinica》2017年第11期1445-1455,共11页Ying-liang LIU Zhi-ming XU Guo-yuan YANG Dian-xu YANG Jun DING Hao CHEN Fang YUAN Heng-li TIAN 
This work was supported by grants from National Natural Science Foundation of China (No 81471245, 81671207, and 81501657), and Shanghai Jiao Tong University Medicine-Engineering Research Fund (YG2016QN20).
Sesamin, a major lignan of sesame oil, was reported to have neuroprotective effects in several brain injury models. However, its protective action in maintaining blood-brain barrier (BBB) integrity has not been stud...
关键词:SESAMIN traumatic brain injury CCl injury bEnd.3 cells oxidative stress apoptosis BBB tight junction proteins 
Inhibition of two stages of melanin synthesis by sesamol,sesamin and sesamolin被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2017年第10期886-895,共10页Montra Srisayam Natthida Weerapreeyakul Kwanjai Kanokmedhakul 
2011 (#542800) and 2012 (#552900), Khon Kaen University Research Funding supported this project
Objective: To investigate the antimelanogenesis properties of three sesame compoundssesamol, sesamin and sesamolin via two stages of melanin synthesis vis-à-vis sunscreen function and enzyme inhibition in melanoma ce...
关键词:SESAMOL SESAMIN SESAMOLIN TYROSINASE TRP-1/TRP-2 Antimelanogenesis 
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