Supported by the NIH(R01AG061034(AR),R35HL15531(AR),R21AG077040(HL),and K08HL140200(JR));the American Heart Association(20CDA35310184(HL)and 19AMFDP34990046(JSG));Sarnoff Cardiovascular Research Foundation Fellowship award(LET and CS);Massachusetts General Hospital Sanchez-Ferguson Faculty Scholar Program(JSG)。
Cardiomyocytes comprise~70%to 85%of the total volume of the adult mammalian heart but only about 25%to 35%of its total number of cells.Advances in single cell and single nuclei RNA sequencing have greatly facilitated ...
This study was supported by grants from the National Key Research and Development Project(2019YFF0301600);National Natural Science Foundation of China(31930055,81870273,and 31871146)。
With the rising incidence of cardiovascular diseases,the concomitant mortality and morbidity impose huge burdens on quality of life and societal costs.It is generally accepted that physical inactivity is one of the ma...