CUBOSOMES

作品数：8被引量：30H指数：4
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相关领域：医药卫生更多>>
相关期刊：《Acta Pharmacologica Sinica》《Journal of Chinese Pharmaceutical Sciences》《Chinese Chemical Letters》《Acta Pharmaceutica Sinica B》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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CD44 and CD221 directed magnetic cubosomes for the targeted delivery of helenalin to rhabdomyosarcoma cells
《Nano Research》2023年第2期2915-2926,共12页Hakmin Mun Yuriy Chaban Tanveer A.Tabish Nanasaheb Thorat Nathan Cowieson CDavid Owen Helen E.Townley 
supported by the Pyongyang University of Science and Technology(PUST)-UK scholarship,the Williams Fund(Oxford Hospitals Charity,No.0085);the UK national electron bio-imaging centre(No.NT32452);the Marie Sklodowska–Curie Grant Agreement(No.840964).
Confining chemotherapy to tumour sites by means of active targeting nanoparticles(NPs)may increase the treatment effectuality while reducing potential side effects.Cubosomes are one of the next-generation drug deliver...
关键词：CUBOSOME active targeting RHABDOMYOSARCOMA helenalin nanoparticle functionalization 
Chirality and chiral functional composites of bicontinuous cubic nanostructured cubosomes
《Chinese Chemical Letters》2022年第3期1488-1492,共5页Deyin Wang Hongkai Liu Wei Wang 
financial support given by the National Natural Science Foundation of China (No. 92061120)。
Molecular self-assembly is the most important strategy for the development of chiral aggregates and chiral functional materials. In this study, we rationally designed and synthesized chiral fluorescent heteroclusters ...
关键词：CHIRALITY Self-assembly NANOSTRUCTURE Composite 
Efficient Access to Inverse Bicontinuous Mesophases via Polymerization-Induced Cooperative Assembly被引量：2
《CCS Chemistry》2021年第8期2214-2225,共12页Fei Lv Zesheng An Peiyi Wu 
support by the National Natural Science Foundation of China(nos.51733003 and 21674059);the Fundamental Research Funds for the Central Universities are thanked.
Polymerization-induced cooperative assembly(PICA)is reported to efficiently access inverse bicontinuous mesophases within particles consisting of amphiphilic block copolymers(BCPs)and solvophobic copolymers.Reversible...
关键词：block copolymers bicontinuous mesophases CUBOSOMES hexasomes polymerizationinduced self-assembly polymerization-induced cooperative assembly reversible additionfragmentation chain transfer 
Recent advances in drug delivery applications of cubosomes,hexosomes,and solid lipid nanoparticles被引量：4
《Acta Pharmaceutica Sinica B》2021年第4期871-885,共15页Anan Yaghmur Huiling Mu 
Financial support to Anan Yaghmur for studies on development of drug nanocarriers based on cubosomes and hexosomes by the Danish Council for Independent Research|Technology and Production Sciences(references 1335-00150b and DFF-7017-00065,Denmark)。
The use of lipid nanocarriers for drug delivery applications is an active research area,and a great interest has particularly been shown in the past two decades.Among different lipid nanocarriers,ISAsomes(Internally s...
关键词：Biological fate CUBOSOMES Drug delivery Hexosomes Inverse non-lamellar liquid crystalline phases Nano-self-assemblies Solid crystalline phases Solid lipid nanoparticles 
Cubosome nanoparticles for enhanced delivery of mitochondria anticancer drug elesclomol and therapeutic monitoring via sub-cellular NAD(P) H multi-photon fluorescence lifetime imaging被引量：4
《Nano Research》2019年第5期991-998,共8页Ana R.Faria Oscar F.Silvestre Christian Maibohm Ricardo M.R.Adao Bruno F.B.Silva Jana B.Nieder 
Elesclomol (ELC) is an anticancer drug inducing mitochondria cytotoxicity through reactive oxygen species.Here,for the first time,we encapsulate the poorly water soluble ELC in monoolein-based cubosomes stabilized wit...
关键词：CUBOSOMES mitoch on dria reactive oxyge n species elesclomol NAD(P)H fluoresce NEE lifetime anticancer therapy 
In vitro and in vivo evaluation of cubosomes containing 5-fluorouracil for liver targeting被引量：9
《Acta Pharmaceutica Sinica B》2015年第1期79-88,共10页Mohamed Nasr Mohamed K.Ghorab Ahmed Abdelazem 
The objective of this study was to prepare cubosomal nanoparticles containing a hydrophilic anticancer drug 5-fluorouracil(5-FU) for liver targeting. Cubosomal dispersions were prepared by disrupting a cubic gel phase...
关键词：5-FLUOROURACIL Hydrophilic drug CUBOSOMES Liver targeting HEPATOTOXICITY 
Tailoring active compounds across biological membranes by cubosomal technology: an updated review被引量：5
《Journal of Chinese Pharmaceutical Sciences》2013年第4期303-313,共11页Vinod K.R. Sravya K. Sandhya S. David Banji Anbazhagan S. Prameela Rani A. 
It is challenging for many drugs to be transported across various biological membranes. Furthermore, development of many drugs gets thwarted owing to their hydrophilic nature. The bioavailability of such drugs, which ...
关键词：Cubosomes Liquid crystal Phase transition Cryo-TEM Birefringent 
Novel vehicle based on cubosomes for ophthalmic delivery of flurbiprofen with low irritancy and high bioavailability被引量：8
《Acta Pharmacologica Sinica》2010年第8期990-998,共9页Shun HAN Jin-qiu SHEN Yong GAN Hai-ming GENG Xin-xin ZHANG Chun-liu ZHU Li GAN 
Aim： To develop a novel vehicle based on cubosomes as an ophthalmic drug delivery system for flurbiprofen （FB） to reduce ocular irritancy and improve bioavailability. Methods： FB-Ioaded cubosomes were prepared usi...
关键词：FLURBIPROFEN CUBOSOMES Ocu!ar drug delive!Y systems cornea! Permeability Ocular irritation 
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