FLURBIPROFEN

作品数:17被引量:30H指数:3
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相关领域:医药卫生更多>>
相关作者:王尊元梁美好赵瑞虹马臻沈正荣更多>>
相关机构:浙江省医学科学院首都医科大学吉林大学更多>>
相关期刊:《Advances in Materials Physics and Chemistry》《Acta Pharmacologica Sinica》《Pharmacology & Pharmacy》《Chinese Medical Journal》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Flurbiprofen microneedle patches for the management of acute postoperative pain
《Nano Research》2024年第8期7493-7503,共11页Huaqing Chu Yanyan Zhang Yuan Yang Jiangtao Xue Cong Li Wei Zhang Zhou Li Hui Zheng 
the National Key Research and Development Program of China(Nos.2022YFB3205602 and 2022YFB3804703);the National Natural Science Foundation of China(Nos.52372174,61875015,and T2125003);the Beijing Natural Science Foundation(Nos.L212046 and L212010);the Fundamental Research Funds for the Central Universities;the Animal Experimentation Ethics Committee of the Cancer Hospital,Chinese Academy of Medical Sciences(Ethical Approval No.NCC2023A291).
Acute postoperative pain is commonly treated with flurbiprofen(FBP),but conventional delivery methods are suboptimal.This study prepared a new non-burst release microneedles(MNs)using genipin cross-linked gelatin(cGel...
关键词:MICRONEEDLE postoperative pain FLURBIPROFEN non-steroid anti-inflammatory drug cross-linked gelatin 
Advancing ophthalmic delivery of flurbiprofen via synergistic chiral resolution and ion-pairing strategies
《Asian Journal of Pharmaceutical Sciences》2024年第3期177-189,共13页Zhining Ma Yuequan Wang Huiyang He Tong Liu Qikun Jiang Xiaohong Hou 
financially supported by the National Postdoctoral Foundation of China(No.2023M730375);Liaoning Province Department of Education Project(No.LJKMZ20221365);the State Key Laboratory of Natural and Biomimetic Drugs(No.K202215)。
Flurbiprofen(FB),a nonsteroidal anti-inflammatory drug,is widely employed in treating ocular inflammation owing to its remarkable anti-inflammatory effects.However,the racemic nature of its commercially available form...
关键词:FLURBIPROFEN ANTI-INFLAMMATORY Ophthalmic delivery Chiral resolution ION-PAIRING 
Effect of flurbiprofen combined with prednisolone on interleukin-6 in elderly surgery patients
《Pharmacology & Pharmacy》2024年第2期15-26,共12页Jiaxin Lin Hui Yang Shaofen Chen Jiao Xu 
Objective: To determine the effect of flurbiprofen combined with prednisolone on interleukin-6 in elderly surgery patients. Methods: In this double-blind randomized controlled study, patients aged 65 to 80 who were un...
关键词:SIRS Systemic Inflammatory Response Syndrome IL-6 INTERLEUKIN-6 CRP C-Reactive Protein 
Efficacy and safety of flurbiprofen cataplasms versus loxoprofen sodium cataplasms in knee osteoarthritis:a randomized controlled trial被引量:2
《Chinese Medical Journal》2023年第18期2187-2194,共8页Dong Li Yinchu Cheng Ping Yuan Ziyang Wu Jiabang Liu Jinfu Kan Kun Zhang Zhanguo Wang Hui Zhang Guangwu Zhang Tao Xue Junxiu Jia Suodi Zhai Zhenpeng Guan 
Background:Clinical trial evidence is limited to identify better topical non-steroidal anti-inflammatory drugs(NSAIDs)for treating knee osteoarthritis(OA).We aimed to compare the clinical efficacy and safety of flurbi...
关键词:Knee osteoarthritis Flurbiprofen cataplasms Loxoprofen cataplasms Knee joint function PAIN Randomized control trial 
The Extent of Solubilization of Flurbiprofen and Ketoprofen by Cetyltrimethylammonium Micelles Using Semi-Equilibrium Dialysis
《Advances in Materials Physics and Chemistry》2020年第4期97-109,共13页Jimmy D. Roach Ibrahim Laswi Malik Mushannen Ali Chaari Mandy Bondaruk 
The partitioning of two non-steroidal anti-inflammatory drugs (NSAIDs), flurbiprofen and ketoprofen, into cationic cetyltrimethylammonium micelles was investigated using semi-equilibrium dialysis at 37℃ in phosphate ...
关键词:FLURBIPROFEN KETOPROFEN CTAB MICELLE SOLUBILIZATION 
Effect of flurbiprofen axetil intervention before induction on incision pain and inflammatory stress response after orthopedic surgery
《Journal of Hainan Medical University》2018年第24期73-76,共4页Hong Liang Tai-Gong Jiang Bai-Zhan Lu 
Objective:To study the effect of flurbiprofen axetil intervention before induction on incision pain and inflammatory stress response after orthopedic surgery.Methods: A total of 86 cases of elderly patients who underw...
关键词:ORTHOPEDIC surgery FLURBIPROFEN axetil Pain MEDIATOR INFLAMMATORY RESPONSE Stress RESPONSE 
Effect of flurbiprofen axetil analgesia after knee replacement on the cytokine contents in serum and joint fluid as well as HPA axis activity
《Journal of Hainan Medical University》2018年第12期25-28,共4页Hao Lin Chun-Xia Liu 
Objective: To investigate the effect of flurbiprofen axetil analgesia after knee replacement on the cytokine contents in serum and joint fluid as well as HPA axis activity. Methods: Patients who underwent knee replace...
关键词:KNEE replacement FLURBIPROFEN axetil CYTOKINE HPA axis 
Association between the physical stability of flurbiprofen suspension and the interaction of HPMC/SDS
《Asian Journal of Pharmaceutical Sciences》2018年第1期63-71,共9页Hongyu Wang Yiwei Sun Baixue Yang Sanming Li 
financially supported by National Natural Science Foundation of China(No.81473161 and No.81273445)
The anionic surfactant sodium dodecylsulfate(SDS) has improved the physical stability of flurbiprofen(FBP) suspension, which was suspended by 0.2%(w/v) hydroxypropylmethyl cellulose(HPMC, K4 M). Therefore, the physica...
关键词:SUSPENSION STABILITY HPMC/SDS Electrical conductivity Viscosity Solubilization Wettability 
Effect of flurbiprofen axetil pretreatment on the pain degree as well as stress hormone and mediator secretion after abdominal surgery
《Journal of Hainan Medical University》2017年第14期37-41,共5页Ying Chen 
Objective:To study the effect of flurbiprofen axetil pretreatment on the pain degree as well as stress hormone and mediator secretion after abdominal surgery.Methods: Patients undergoing abdominal surgery in our hospi...
关键词:FLURBIPROFEN axetil PAIN CYTOKINE Stress 
S(+)-Flurbiprofen Shows Potent PGE2 Inhibitory Activity in Inflammatory Cells, Superior Cell Transport Activity and Skin Permeability
《Pharmacology & Pharmacy》2016年第8期305-312,共8页Yoshihisa Toda Masanori Sugimoto Hiromi Endo Miho Kamezawa Ichimaro Yamada Shogo Kawabata Shinsuke Kaku Noboru Otsuka Hideo Matsumoto 
We developed a novel topical non-steroidal anti-inflammatory drug (NSAID)patch, S(+)-flurbiprofen plaster, (SFPP), containing S(+)-flurbiprofen (SFP), an enantiomer of flurbiprofen (FP). In a previous study conducted ...
关键词:NSAIDS S(+)-Flurbiprofen CYCLOOXYGENASE Skin Permeability 
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