the financial support from the National Natural Science Foundation of China(22001121);Nanjing Tech University。
A catalyst-free and additive-free ring-opening reaction of polyfluoroalkyl peroxides,triethylenediamine(DABCO),and 1,2-dichloroethane(DCE)has been developed for the defluorinative synthesis of structurally diverse pip...
Financial support for this study is from the"Double First-Class"University project(CPU2018GY08,China);the 111 Project from Ministry of Education of China and the State Administration of Foreign Export Affairs of China(B18056);the National New Drug Innovation Major Project(2018ZX09711-001-007).
Sarcaglarols A-D(1-4),two pairs of lindenane-monoterpene heterodimers fused by a 1,2-dioxane moiety,were discovered and isolated from the leaves of Sarcandra glabra guided by MS/MS molecular networking-based strategy....
This work was supported by the National Natural Science Foundation of China (21532002, 21672244, 21372248) and Chinese Academy of Sciences.
A range of qinghaosu (artemisinin) analogues were synthesized from modified dihydroqinghao acid/aldehyde using dark singlet oxygen to trigger off the key step of the trioxane formation. The newly accessed 1,2,4-trio...
Project supported by the National Natural Science Foundation of China (Nos. 20025207. 20272071, 20372075 and 20321202) and the Chinese Academy of Sciences (No. KGCX2-SW-209). Dedicated to Professor Xikui Jiang on the occasion of his 80th birthday.
Synthesis of five simple analogues of peroxyplakoric acid by using Kobayashi's method to construct the key 1,2-dioxane core is detailed.
Project supported by the National Natural Science Foundation of China (Nos. 20025207, 20272071, 20372075, 20321202), the Chinese Academy ot Sciences (“Knowledge Innovation”project, KGCX2-SW-209), and the Major State Basic Research Development Program (No. G2000077502) of China.
Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2-dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method...