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supported by the National Natural Science Foundation of China(82273784,China);the Research and Develop Program,West China Hospital of Stomatology Sichuan University(RD-03-202004,China);the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYYC 21002,ZYGD23025,China);the Clinical Research Innovation Project,West China Hospital,Sichuan University(2019 HXCX006,China);the Science and Technology Major Project of Tibetan Autonomous Region of China(XZ202201ZD0001G,China);the Sichuan Science and Technology Program(2023 ZYD0168,China).
Multifunctional therapeutics have emerged as a solution to the constraints imposed by drugs with singular or insufficient therapeutic effects.The primary challenge is to integrate diverse pharmacophores within a singl...
Postoperative cognitive dysfunction(POCD)remains a major issue that worsens the prognosis of elderly surgery patients.This article reviews the current research on the effect of different anesthesia methods and commonl...
This work is financially supported by the National Key Research and Development Program of China(No.2022YFF1101002);Jiangsu Association for Science and Technology Youth Science and Technology Talent Support Project(No.TJ-2021-049).
Anesthetic residues in fish represent a potential risk to human health.Therefore,it is important to develop a sensitive and broad-specific method for the detection of anesthetics.In this study,we developed a colloidal...
Although the GABAA receptor(GABAAR)has been proposed as the main action site for sevoflurane,isoflurane,halothane,enflurane,propofol,and benzodiazepines(BZDs),binding of these anesthetics with high-resolution structur...
BACKGROUND With aging,four major facial retaining ligaments become elongated,leading to facial sagging and wrinkling.Even though synthetic fillers are popular,however,it cannot address the problems of soft tissue desc...
BACKGROUND Hypovolemic shock can lead to life-threatening organ dysfunction,and adequate fluid administration is a fundamental therapy.Traditionally,parameters such as vital signs,central venous pressure,and urine out...
Tumor promoters, apoptosis and autophagy modulators, chemotherapy drugs, and endogenous steroids demonstrate molecular similarity relative to cyclic nucleotide structure. This study explores relative molecular similar...
Nitrous oxide is one of the most commonly used inhalational anesthetic agents used in practice.It is a cost-effective,pleasant,safe,and versatile anesthetic agent with many desirable properties like good quality analg...
Objective: to analyze the sedation, analgesia and safety of elderly patients undergoing ERCP through dexmedetomidine and anesthetics. Methods: 90 patients with ERCP in our hospital from June 2018 to June 2021 were ran...
Beijing municipal administration of hospitals clinical medicine development of special funding support(Code:ZYLX201808);Beijing Municipal Health Commission(Code:Jing2019-2)。
Background:Resting-state functional magnetic resonance imaging(rs-fMRI)is a promising method for the study of brain function.Typically,rs-fMRI is performed on anesthetized animals.Although different functional connect...