云南高校图书馆联盟文献共享服务平台- PHOSPHOPROTEIN

PHOSPHOPROTEIN: 作品数：24被引量：40H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李文智王忠邵志强王健明何相飞更多>>; 相关机构：上海交通大学医学院附属第九人民医院临沂市人民医院核医学国家重点实验室福建省妇幼保健院更多>>; 相关期刊：《Cancer Communications》《Neuroscience Bulletin》《微生物学杂志》《Acta Biochimica et Biophysica Sinica》更多>>; 相关基金：国家自然科学基金湖北省自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>

Quercetin inhibits truncated isoform of dopamine-and cAMP-regulated phosphoprotein as adjuvant treatment for trastuzumab therapy resistance in HER2-positive breast cancer: 《Food Science and Human Wellness》2024年第5期2653-2667,共15页Han-Sheng Chang Tzu-Chun Cheng Shih-Hsin Tu Chih-Hsiung Wu You-Cheng Liao Jungshan Chang Min-Hsiung Pan Li-Ching Chen Yuan-Soon Ho; The National Science and Technology Council of Taiwan funded this study.; Trastuzumab resistance is one of the causes of poor prognosis in patients with human epidermal growth factor receptor 2(HER2)-positive(HER2+)breast cancer(BC).The truncated isoform of dopamine-and cAMPregulated phosph...; 关键词：p95-Human epidermal growth factor receptor 2 (HER2) HER2-positive breast cancer QUERCETIN Trastuzumab resistance Truncated isoform of dopamine-and cAMPregulated PHOSPHOPROTEIN

过表达NOLC1诱导人非小细胞肺癌细胞凋亡: 《微生物学杂志》2024年第2期87-96,共10页杜亚兰张茂盛王旌羽张璐燕周常博佘晓双郑方亮朱春玉; 辽宁省教育厅一般项目(LJC201910);辽宁省教育厅服务地方项目(LJKFZ20220179)。; 人核仁磷酸化蛋白1(Nucleolar and coiledbody phosphoprotein 1,NOLC1)在癌症的发生发展过程中起着至关重要的调控作用,为探讨NOLC1对肺癌细胞的作用,本研究通过Gateway系统构建重组NOLC1腺病毒载体,成功包装NOLC1腺病毒后,分别感染正...; 关键词：NOLC1(Nucleolar and coiledbody phosphoprotein 1) 肺癌细胞腺病毒载体过表达细胞凋亡

Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth: 《World Journal of Gastrointestinal Oncology》2023年第11期1936-1950,共15页Kuan He Chao-Zheng Xie Ya Li Zhen-Zhou Chen Shi-Hao Xu Si-Qi Huang Jian-Guo Yang Zheng-QiangWei Xu-Dong Peng; Supported by Chongqing Key Diseases Research and Application Demonstration Program,No.2019ZX003;General Project of Chongqing Nature Science Foundation,No.cstc2021jcyj-msxmX0283.; BACKGROUND Dopamine and cyclic adenosine monophosphate(cAMP)-regulated phosphop-rotein with an apparent Mr of 32000(DARPP-32)is a protein that is involved in regulating dopamine and cAMP signaling pathways in the brai...; 关键词：Colorectal cancer Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 Proliferation Migration Phosphoinositide 3-kinase Akt

Cancer-associated fibroblast-derived secreted phosphoprotein 1 contributes to resistance of hepatocellular carcinoma to sorafenib and lenvatinib被引量：13: 《Cancer Communications》2023年第4期455-479,共25页JungWoo Eun Jung Hwan Yoon Hye Ri Ahn Seokhwi Kim Young Bae Kim Su Bin Lim Won Park TaeWook Kang Geum Ok Baek Moon Gyeong Yoon Ju A Son Ji HyangWeon Soon Sun Kim Hyo Jung Cho Jae Youn Cheong; Background:Cancer-associated fibroblasts(CAFs)play an important role in the induction of chemo-resistance.This study aimed to clarify the mechanism underlying CAF-mediated resistance to two tyrosine kinase inhibitors(...; 关键词：drug resistance epithelial-to-mesenchymal transition hepatocellular carcinoma secreted phosphoprotein 1

Secreted phosphoprotein 1 promotes angiogenesis of glioblastoma through upregulating PSMA expression via transcription factor HIF1α: 《Acta Biochimica et Biophysica Sinica》2023年第3期417-425,共9页Wenjing Tu Hui Zheng Liangdong Li Changshuai Zhou Mingtao Feng Lei Chen Deheng Li Xin Chen Bin Hao Huaping Sun Yiqun Cao Yang Gao; supported by the grants from the National Natural Science Foundation of China(Nos.82103429 and 82173177);the Foundation of Tenth People's Hospital(No.04.03.18.088);the Foundation of Shanghai Municipal Health Bureau(No.20204Y0264).; Glioblastoma multiforme(GBM)is a highly vascularized malignant brain tumor.Our previous study showed that prostate-specific membrane antigen(PSMA)promotes angiogenesis of GBM.However,the specific mechanism underlying ...; 关键词：glioblastoma multiforme SPP1 PSMA ANGIOGENESIS HIF1Α

Customized synthesis of phosphoprotein bearing phosphoserine or its nonhydrolyzable analog: 《Synthetic and Systems Biotechnology》2023年第1期69-78,共10页Dong Liu Yingying Liu Hua-Zhen Duan Xinjie Chen Yanan Wang Ting Wang Qing Yu Yong-Xiang Chen Yuan Lu; supported by the National Natural Science Foundation of China (21878173,22177059);National Key R&D Program of China (2018YFA0901700,2021YFC2103900);a grant from the Institute Guo Qiang,Tsinghua University (2021GQG1016).; Studies on the mechanism of protein phosphorylation and therapeutic interventions of its related molecular processes are limited by the difficulty in the production of purpose-built phosphoproteins harboring site-spec...; 关键词：Cell-free synthetic biology PHOSPHOPROTEIN PHOSPHORYLATION Orthogonal translation system Nonhydrolyzable analog

A high level of secreted phosphoprotein 1 is associated with macrophage infiltration and poor prognosis in hepatocellular carcinoma: 《iLIVER》2023年第1期26-35,共10页Jianping Song Jingxian Sun Shuhong Jing Tingxiao Zhang Jianlei Wang Yanfeng Liu; supported by Shandong Natural Science Foundation[grant number ZR2021MH339].; Background and aims:Secreted phosphoprotein 1(SPP1)functions in several physiological processes.The role of SPP1 expression in the prognosis and tumor immunity of hepatocellular carcinoma(HCC)is unknown.The aim of thi...; 关键词：Hepatocellular carcinoma Secreted phosphoprotein 1 PROGNOSIS Promoter demethylation Tumor immunity

M_(4) muscarinic receptors regulates dopamine/DARPP-32 signaling and glutamate transmis⁃sion to balance dopaminergic D1 function in mouse dorsal striatum: 《中国药理学与毒理学杂志》2021年第9期689-689,共1页ZHOU Hu ZHANG Jing-xin LI Xing SHI Hua-xiang SUI Xin WANG Yong-an LI Jin WANG Li-yun; OBJECTIVE Abnormal striatal dopaminergic and glutamatergic neurotransmis⁃sion is central to the pathophysiology of schizo⁃phrenia.In this study,we investigated the roles of M4 receptor interplay with D1 signaling in s...; 关键词：dorsal striatum dopamine receptor 1 muscarinic acetylcholine M4 receptor dopamine-and cAMP-regulated phosphoprotein of 32 ku

Sumoylation of Human Parainfluenza Virus Type 3 Phosphoprotein Correlates with A Reduction in Viral Replication被引量：1: 《Virologica Sinica》2021年第3期438-448,共11页Qi Cheng Wenjing Huai Xiaoyan Wu Mingzhou Chen; supported by grants from National Key R&D Program of China (2017YFA0505801);the National Natural Science Foundation of China (81825015, 81871650 and 31630086);National Science and Technology Major Project (2018ZX10101004);the Natural Science Foundation of Hubei Province Innovation Group (2017CFA022);Advanced Customer Cultivation Project of Wuhan National Biosafety Laboratory (2019ACCP-MS06)。; Human parainfluenza virus type 3(HPIV3), a member of the Paramyxoviridae family, can cause lower respiratory disease in infants and young children. The phosphoprotein(P) of HPIV3 is an essential cofactor of the viral ...; 关键词：Human parainfluenza virus type 3(HPIV3) PHOSPHOPROTEIN SUMOYLATION REPLICATION Viral replication

Host protein ABCE1 interacts with the viral phosphoprotein and promotes rabies virus replication: 《Biosafety and Health》2020年第3期157-163,共7页Xing Liu Jiwen Zhang Fang Li Yibrah Tekle Hagoss Weldu Tesfagaber Lulu Wang Zilong Wang Dongming Zhao Zhigao Bu; supported by the National Key R&D Program of China(2018YFC1200601);Fundamental Research Funds for Central Non-profit Scientific Institution;a grant from the State Key Laboratory of Veterinary Biotechnology Program(SKLVBP201801).; Rabies virus(RABV)phosphoprotein(P)plays an important role in disrupting host interferon(IFN)-mediated antiviral immune response.ABCE1 is known as an RNase L inhibitor that negatively regulates the 2′,5′-oligoadenyl...; 关键词：Rabies virus ABCE1 REPLICATION PHOSPHOPROTEIN INTERACTION

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