SYNAPTOTAGMINS

作品数：5被引量：11H指数：2
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Synaptotagmins family affect glucose transport in retinal pigment epithelial cells through their ubiquitination-mediated degradation and glucose transporter-1 regulation
《World Journal of Diabetes》2024年第5期958-976,共19页Hong Xu Li-Bo Zhang Yi-Yi Luo Ling Wang Ye-Pin Zhang Pei-Qi Chen Xue-Ying Ba Jian Han Heng Luo 
BACKGROUND Synaptotagmins(SYTs)are a family of 17 membrane transporters that function as calcium ion sensors during the release of Ca2+-dependent neurotransmitters and hormones.However,few studies have reported whethe...
关键词：Diabetic retinopathy Glucose transporter-1 Synaptotagmin 4 PARKIN Myelin transcription factor 1 
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI（4,5）P2 and extended synaptotagmins被引量：9
《Science China(Life Sciences)》2019年第9期1117-1135,共19页Jian Xiao Jie Luo Ao Hu Ting Xiao Meixin Li Zekai Kong Luyi Jiang Zimu Zhou Yacheng Liao Chang Xie Beibei Chu Honghua Miao Boliang Li Xiongjie Shi Bao-Liang Song 
supported by the National Natural Science Foundation of China (91754102, 31771568, 31690102, 31600651, 31701030);National Key Research and Development Project of the Ministry of Science and Technology of China (2016YFA0500100);Shenzhen City Technology Basic Research Program (JCYJ20170818144026198);Science and Technology Department of Hubei Province (2017CFB617);the 111 Project of Ministry of Education of China (B16036)
Most mammalian cells take up cholesterol from low-density lipoproteins(LDLs) via receptor-mediated endocytosis.After reaching lysosomes,LDL-derived cholesterol continues to transport to downstream organelles including...
关键词：PEROXISOME ER MEMBRANE CONTACTS E-Syts PI(4 5)P2 
Extended synaptotagmins, peroxisome-endoplasmic reticulum contact and cholesterol transport被引量：3
《Science China(Life Sciences)》2019年第9期1266-1269,共4页Hongyuan Yang 
Cholesterol is an essential component of mammalian cell membranes where it regulates membrane permeability,fluidity,fusion and cell signaling pathways (Chang et al.,2006).Cholesterol must be sorted precisely and trans...
关键词：membrane PERMEABILITY CORONARY heart disease cellular ORGANELLE 
Synaptotagmins： links to human disease
《Journal of Translational Neuroscience》2017年第4期24-30,共7页Wanru Li Claire Xi Zhang 
The author was supported by grants from the Beijing Natural Science Foundation Program and the Scientifc Research Key Program of Beijing Municipal Commission of Education （KZ201510025023）, the National Natural Science Foundation of China （31471085）.
Synaptotagmins （Syts） are a large family of integral membrane proteins that regulate synaptic function and membrane traffcking. Emerging evidences show involvement of Syts in human diseases. Here, we review the rece...
关键词：synaptotagmins （Syts） NEURODEGENERATION 
Arabidopsis Synaptotagmin 2 Participates in Pollen Germination and Tube Growth and Is Delivered to Plasma Membrane via Conventional Secretion被引量：2
《Molecular Plant》2015年第12期1737-1750,共14页Hui Wang Shengcheng Han Wei Siao Chunqing Song Yun Xiang Xiaorong Wu Pengyu Cheng Hongjuan Li JAn Jasik Karol Micieta JAn Turna Boris Voigtt Frantisek Baluska Jin Liu Yingdian Wang Heping Zhao 
Arabidopsis synaptotagmin 2 （SYT2） has been reported to participate in an unconventional secretory pathway in somatic cells. Our results showed that SYT2 was expressed mainly in the pollen ofArabidopsis thaliana. Th...
关键词：SYNAPTOTAGMINS pollen germination calcium-dependent phospholipid binding C2 domains conventional secretion 
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