PEROXISOME

作品数：101被引量：444H指数：13
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Peroxisome and pexophagy in neurological diseases
《Fundamental Research》2024年第6期1389-1397,共9页Weilin Xu Jun Yan Anwen Shao Cameron Lenahan Liansheng Gao Haijian Wu Jingwei Zheng Jianmin Zhang John H.Zhang 
supported by the National Institutes of Health(NS084921,NS082184,and NS43338);National Natural Science Foundation of China(82001231,82001299);Zhejiang Provincial Natural Science Foundation of China(LQ21H090009);Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China under Grant(LHDMZ22H300014).
Peroxisomes and pexophagy have gained increasing attention in their role within the central nervous system(CNS)in recent years.In this review,we comprehensively discussed the physiological and pathological mech-anisms...
关键词：PEROXISOME PEXOPHAGY AUTOPHAGY Neurological diseases NEUROPROTECTION 
Neuroprotective effects of G9a inhibition through modulation of peroxisome-proliferator activator receptor gamma-dependent pathways by miR-128被引量：1
《Neural Regeneration Research》2024年第11期2532-2542,共11页Aina Bellver-Sanchis Pedro AAvila-López Iva Tic David Valle-García Marta Ribalta-Vilella Luis Labrador Deb Ranjan Banerjee Ana Guerrero Gemma Casadesus Coralie Poulard Mercè Pallàs Christian Grinán-Ferré 
supported by the Ministerio de Economía,Industria y Competitividad(Agencia Estatal de Investigación,AEI,to CGF and MP);Fondo Europeo de Desarrollo Regional(MINECO-FEDER)(PID2022-139016OA-I00,PDC2022-133441-I00,to CGF and MP),Generalitat de Catalunya(2021 SGR 00357;to CGF and MP);co-financed by Secretaria d’Universitats i Recerca del Departament d’Empresai Coneixement de la Generalitat de Catalunya 2021(Llavor 00086,to CGF);the recipient of an Alzheimer’s Association Research Fellowship(AARF-21-848511);the Agència de Gestiód’Ajuts Universitaris i de Recerca(AGAUR)for her FI-SDUR fellowship(2021FISDU 00182).
Dysregulation of G9a,a histone-lysine N-methyltransferase,has been observed in Alzheimer’s disease and has been correlated with increased levels of chronic inflammation and oxidative stress.Likewise,microRNAs are inv...
关键词：aging cognitive decline epigenetics G9a inhibition microRNAs miR-128 peroxisome-proliferator activator receptorγ(PPARγ) PPARG SAMP8 
Activation of LONP1 by 84-B10 alleviates aristolochic acid nephropathy via re-establishing mitochondrial and peroxisomal homeostasis
《Chinese Journal of Natural Medicines》2024年第9期808-821,共14页XU Xinyue ZHU Wenping MIAO Mengqiu BAI Mi FAN Jiaojiao NIU Yujia LI Yuting ZHANG Aihua JIA Zhanjun WU Mengqiu 
supported by the National Key Research and Development Program of China (Nos. 2019YFA0802-702-1, 2022YFC2705100, 2022YFC2705105);the National Natural Science Foundation of China (Nos. 82070701, 82090022, and 8183-0020);the Natural Science Foundation of Jiangsu Province (No. BK20231130);the Social Development Foundation of Jiangsu Province(No. BE2021607);the “333” Talent Plan of Jiangsu Province (No.333-2022001);the Medical Research Project from Jiangsu Health and Health Commission (No. Z2022071);the Outstanding Youth Project from Nanjing Health and Health Commission (No.JQX22010)。
Pharmaceutical formulations derived from Aristolochiaceae herbs, which contain aristolochic acids(AAs), are widely used for medicinal purposes. However, exposure to these plants and isolated AAs is linked to renal tox...
关键词：Aristolochic acid nephropathy 84-B10 LONP1 MITOCHONDRION PEROXISOME 
Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis
《The Journal of Biomedical Research》2024年第1期24-36,共13页Yejin Yao Baolu Shi Xiangzheng Zhang Xin Wang Shuangyue Li Ying Yao Yueshuai Guo Dingdong Chen Bing Wang Yan Yuan Jiahao Sha Xuejiang Guo 
supported by grants from the National Natural Science Foundation of China(Grant No.31890784 to J.S.);National Key R&D Program(Grant No.2021YFC2700200 to X.G.);National Natural Science Foundation of China(Grant Nos.92068109 and 82122025 to Yan Yuan);Natural Science Foundation of the Jiangsu Higher Education Institutions of China(Grant No.21KJA310007 to Yan Yuan);Science Foundation of Gusu School(Grant No.GSKY20220101 to J.S.).
Peroxisomes are organelles enclosed by a single membrane and are present in various species.The abruption of peroxisomes is correlated with peroxisome biogenesis disorders and single peroxisomal enzyme deficiencies th...
关键词：male infertility SPERMIOGENESIS PEROXISOME oxidative stress PEX3 
Herpesviral interplay with peroxisome:An underexplored viral niche
《Genes & Diseases》2023年第4期1133-1135,共3页Omkar Indari Süleyman Ergün Srikanth Karnati Hem Chandra Jha 
supported by the Indo-German Science&Technology Centre(IGSTC)Industrial Fellowship program(No.IGSTC/SING-2022/40/2021e22/332).
Herpesviruses are smart pathogens that can infect and have lifelong persistence inside the host.Many human herpes-viruses have been shown to affect human health in immu-nologically challenged conditions.Mostly the her...
关键词：HERPES KAPOSI SARCOMA 
Lysosomal cholesterol accumulation is commonly found in most peroxisomal disorders and reversed by 2-hydroxypropyl-β-cyclodextrin
《Science China(Life Sciences)》2023年第8期1786-1799,共14页Lewei Dong Jian Xiao Shuai Liu Gang Deng Yacheng Liao Beibei Chu Xiaolu Zhao Bao-Liang Song Jie Luo 
supported by the China Postdoctoral Science Foundation Grant(2021M692478);the Ministry of Science and Technology of China(2018YFA0800703);the National Natural Science Foundation of China(32293203,31771568);111 Project of Ministry of Education of China(B16036);the support from the Tencent Foundation through the XPLORER PRIZE。
Peroxisomal disorders(PDs)are a heterogenous group of diseases caused by defects in peroxisome biogenesis or functions.Xlinked adrenoleukodystrophy is the most prevalent form of PDs and results from mutations in the A...
关键词：CHOLESTEROL PEROXISOME LYSOSOME peroxisomal disorders X-ALD CYCLODEXTRIN ABCD1 VLCFA 
Protein ubiquitination in plant peroxisomes被引量：1
《Journal of Integrative Plant Biology》2023年第2期371-380,共10页Delara Akhter Yuchan Zhang Jianping Hu Ronghui Pan 
supported by the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(No.2019R01002);Key Research Project of Zhejiang Laboratory(No.2021PE0AC04);Scientific Research Fund of Zhejiang Provincial Education Department(No.Y202148338);Zhejiang University Student Research Practice Program(No.P2021041)to R.P.;by the National Science Foundation(No.MCB 2148206);US Department of Energy(No.DEFG02-91ER20021)to J.H。
Protein ubiquitination regulates diverse cellular processes in eukaryotic organisms,from growth and development to stress response.Proteins subjected to ubiquitination can be found in virtually all subcellular locatio...
关键词：peroxins PEROXISOME peroxisome biogenesis peroxisome metabolism PEXOPHAGY UBIQUITINATION 
The mechanistic target of rapamycin complex 1 pathway involved in hepatic gluconeogenesis through peroxisome-proliferator-activated receptorγcoactivator-1a被引量：3
《Animal Nutrition》2022年第4期121-131,共11页Guoyan Wang Jun Zhang Shengru Wu Senlin Qin Yining Zheng Chao Xia Huijun Geng Junhu Yao Lu Deng 
National Natural Science Foundation of China,China(grant numbers 32070782,32072761)。
Cattle can efficiently perform de novo generation of glucose through hepatic gluconeogenesis to meet post-weaning glucose demand.Substantial evidence points to cattle and non-ruminant animals being characterized by ph...
关键词：Hepatic gluconeogenesis CATTLE mTORC1 Peroxisome-proliferator-activated receptor γcoactivator-1a 
Comparative proteomics analysis of Pichia pastoris cultivating in glucose and methanol被引量：2
《Synthetic and Systems Biotechnology》2022年第3期862-868,共7页Rui Hou Linhui Gao Jianhui Liu Zhen Liang Yongjin J.Zhou Lihua Zhang Yukui Zhang 
supported by National Natural Science Foundation of China(22161142008,M-0246);DMTO research grant(grant no.DICP DMTO_(2)01701)from Dalian institute of Chemical Physics,CAS.
The methylotrophic yeast Pichia pastoris(syn.Komagataella phaffii)has been extensively engineered for protein production,and is attracting attention as a chassis cell for methanol biotransformation toward production o...
关键词：PROTEOMICS PEROXISOME Methanol metabolism Systems biology 
Characterization of laccase gene StLAC6 and its involvement in the pathogenicity and peroxisome function in Setosphaeria turcica被引量：1
《Journal of Integrative Agriculture》2022年第7期2019-2030,共12页LIU Ning ZHANG Qian-qian JIA Hui ZHAO Bin ZHU Zi-ping CAO Zhi-yan DONG Jin-gao 
supported by the grants from the National Natural Science Foundation of China(31901827);the China Agriculture Research System(CARS-02);the Natural Science Foundation of Hebei Province,China(C2020204039);the Key Research and Development Projects of Hebei Province(20326510D);the Hebei Province Projects of Overseas Foundation(C20190508)。
Laccases, as a kind of multicopper oxidase, play an important role in pigment synthesis and growth in fungi and are involved in their interactions with host plants. In Setosphaeria turcica, 9 laccase-like multicopper ...
关键词：Setosphaeria turcica LACCASE StLAC6 PEROXISOME fungicides 
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