MITOCHONDRION

作品数:67被引量:232H指数:7
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相关领域:医药卫生生物学更多>>
相关作者:袁宗飞徐是雄国凤利胡适宜王健学更多>>
相关机构:北京大学香港大学中国农业大学河北大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>
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Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2
《Neural Regeneration Research》2025年第6期1776-1788,共13页Zige Jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing Xin Yijing Zhao Yan Song Yahong Cheng Tong Li Zhen Wang 
supported by the National Natural Science Foundation of China,Nos.82271327 (to ZW),82072535 (to ZW),81873768 (to ZW),and 82001253 (to TL)。
The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and ce...
关键词:apoptosis CYSTATHIONINE-Β-SYNTHASE nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide MITOCHONDRION NEUROPLASTICITY oxidative stress quinolinic acid reactive oxygen species 
PPR21 is involved in the splicing of nad2 introns via interacting with PPR-SMR1 and SPR2 and is essential to maize seed development
《Journal of Genetics and Genomics》2025年第3期379-387,共9页Yan-Zhuo Yang Xin-Yuan Liu Song Gao Shu-Guang Zhang Bao-Cai Tan 
supported by the National Natural Science Foundation of China(32072126 and 32230075);the Shandong Provincial Natural Science Foundation(ZR2019MC005).
Pentatricopeptide repeat(PPR)proteins are a large group of eukaryote-specific RNA-binding proteins that play pivotal roles in plant organelle gene expression.Here,we report the function of PPR21 in mitochondrial intro...
关键词:Intron splicing Maize(Zea mays) MITOCHONDRION PPR21 Seed development Small MutS-related domain-containing PPR protein 1(PPR-SMR1) SPR2 
Involvement of mitochondrial TRPV3 in cardiac hypertrophy induced by pressure overload in rats
《生理学报》2024年第5期703-716,共14页ZHU Mei-Ping ZHANG Bing-Yi LIAN Ting TAN Yuan-Jia CHANG Lin-Lin XU Pan ZHANG Jin-Yi DU Yan-Huan XIONG Zhen-Yu DU Qiong ZHANG Shi-Zhong 
supported by the National Natural Science Foundation of China (No. 30872716);the Natural Science Foundation of Hubei Province,China (No. 2015CFB288);Open Foundation of Hubei Province Key Laboratory of Tumor Microenvironment and immunotherapy (No. 2023KZL06)。
Mitochondria play an important role in pressure overload-induced cardiac hypertrophy.The present study aimed to investigate the role of mitochondrial transient receptor potential vanilloid 3(TRPV3)in myocardial hypert...
关键词:cardiac hypertrophy pressure overload MITOCHONDRION TRPV3/NOX4 
Don´t give up on mitochondria as a target for the treatment of diabetes and its complications
《World Journal of Diabetes》2024年第10期2015-2021,共7页Christian Cortés-Rojo Manuel Alejandro Vargas-Vargas 
Supported by Instituto de Ciencia,Tecnología e Innovación-Gobierno del Estado de Michoacán,México,No.ICTI-PICIR23-063;Programa Proyectos de Investigación Financiados 2024,Coordinación de Investigación Científica,Universidad Michoacana de San Nicolás de Hidalgo,México.
In this editorial,we discuss an article by Wang et al,focusing on the role of mitochondria in peripheral insulin resistance and insulin secretion.Despite numerous in vitro and pre-clinical studies supporting the invol...
关键词:Diabetes mellitus Insulin resistance MITOCHONDRION Mitochondrial dysfunction MITOQ MitoTEMPO SKQ Elamipretide Mitochondria transplantation Glycemic control 
Activation of LONP1 by 84-B10 alleviates aristolochic acid nephropathy via re-establishing mitochondrial and peroxisomal homeostasis
《Chinese Journal of Natural Medicines》2024年第9期808-821,共14页XU Xinyue ZHU Wenping MIAO Mengqiu BAI Mi FAN Jiaojiao NIU Yujia LI Yuting ZHANG Aihua JIA Zhanjun WU Mengqiu 
supported by the National Key Research and Development Program of China (Nos. 2019YFA0802-702-1, 2022YFC2705100, 2022YFC2705105);the National Natural Science Foundation of China (Nos. 82070701, 82090022, and 8183-0020);the Natural Science Foundation of Jiangsu Province (No. BK20231130);the Social Development Foundation of Jiangsu Province(No. BE2021607);the “333” Talent Plan of Jiangsu Province (No.333-2022001);the Medical Research Project from Jiangsu Health and Health Commission (No. Z2022071);the Outstanding Youth Project from Nanjing Health and Health Commission (No.JQX22010)。
Pharmaceutical formulations derived from Aristolochiaceae herbs, which contain aristolochic acids(AAs), are widely used for medicinal purposes. However, exposure to these plants and isolated AAs is linked to renal tox...
关键词:Aristolochic acid nephropathy 84-B10 LONP1 MITOCHONDRION PEROXISOME 
Biophoton signaling in mediation of cell-to-cell communication and radiation-induced bystander effects
《Radiation Medicine and Protection》2024年第3期145-160,共16页Jian Tong 
This paper presents a comprehensive overview of the historical trajectory and development in biophoton studies over the past 100 years,with a particular focus on the recent progress regarding the pivotal role of bioph...
关键词:BIOPHOTON Radiation-induced bystander effect Ionizing radiation Cell-to-cell communication MITOCHONDRION EXOSOME 
KLF4 facilitates chromatin accessibility remodeling in porcine early embryos被引量:3
《Science China(Life Sciences)》2024年第1期96-112,共17页Wei Zhu Guowei Bu Ruifeng Hu Jixiang Zhang Lianyong Qiao Kai Zhou Tingting Wang Qiao Li Jingjing Zhang Linhui Wu Yali Xie Taotao Hu Shichun Yang Jiaqi Guan Xiaoyu Chu Juanjuan Shi Xia Zhang Falong Lu Xin Liu Yi-Liang Miao 
This work was supported by the National Natural Science Foundation of China(31902161);the National Key Research and Development Program of China(2022YFD1302201,2018YFA0107001);Strategic Priority Research Program of Chinese Academy of Sciences(XDA24020203);Key Research and Development Program of Hubei Province(2021BBA221);Major Project of Hubei Hongshan Laboratory(2021hszd003);Foundation of Key Laboratory of Animal Genetics,Breeding and Reproduction in the Plateau Mountainous Region,Ministry of Education,Guizhou University(QJHKY[2022]373).
Chromatin accessibility remodeling driven by pioneer factors is critical for the development of early embryos.Current studies have illustrated several pioneer factors as being important for agricultural animals,but wh...
关键词:porcine embryos liDNase-seq chromatin accessibility KLF4 MITOCHONDRION lipid droplets 
A peptide chain release factor 2a gene regulates maize kernel development by modulating mitochondrial function
《The Crop Journal》2023年第6期1731-1741,共11页Hui Zhang Yijian Feng Kunyang Song Guofang Li Jiao Jin Jingjing Gao Yongtian Qin Hongqiu Wang Jinpeng Cheng Zonghua Liu Jihua Tang Zhiyuan Fu 
the National Natural Science Foundation of China(31971893,U2004144);the Key Technologies R&D Program of Henan Province(232102111080,212102110043);Academician Expert Workstation(202305AF150082).
Mitochondrial protein translation that is essential for aerobic energy production includes four essential steps of the mitochondrial ribosome cycle,namely,initiation,elongation,termination of the polypeptide,and ribos...
关键词:Embryo lethality MITOCHONDRION Peptide release factor 2 Zea mays 
Evolutionary genetics of wheat mitochondrial genomes
《The Crop Journal》2023年第6期1774-1781,共8页Hui-Lin Hu Fan Zhang Pei Wang Fu-Hao Lu 
the 111 Project(D16014).
The Triticum-Aegilops complex provides ideal models for the study of polyploidization,and mitochondrial genomes(mtDNA)can be used to trace cytoplasmic inheritance and energy production following polyploidization.In th...
关键词:WHEAT MITOCHONDRION MTDNA Comparative genomics POLYPLOIDIZATION 
Enhanced Bioenergy Transformation by Metal-Free Electrozyme-Based Mitochondrion Nanoarchitectonics
《CCS Chemistry》2023年第7期1644-1652,共9页Tonghui Wang Jinbo Fei Zhenzhen Dong Xia Xu Weiguang Dong Junbai Li 
This work was supported by the NationalNatural Science Foundation of China(grant nos.221930301,21961142022,22072160,and 21872150);.J.F.particularly thanks to Institute of Chemistry,CAS(grant no.Y6290512B1).
Herein,we couple a synthetic electrozyme in a supramolecule-assembled nanoarchitecture to achieve enhanced bioenergy transformation by mimicking mitochondrial oxidative phosphorylation.Different from the natural count...
关键词:molecular assembly BIOENERGY nanozyme BIOCATALYSIS nanoarchitectonics 
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