CYSTATHIONINE-Β-SYNTHASE

作品数：4被引量：5H指数：2
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相关领域：医药卫生更多>>
相关作者：段肖翠武宇明更多>>
相关机构：首都医科大学河北医科大学更多>>
相关期刊：《Neural Regeneration Research》《International Journal of Ophthalmology(English edition)》更多>>
相关基金：国家自然科学基金更多>>
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Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2
《Neural Regeneration Research》2025年第6期1776-1788,共13页Zige Jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing Xin Yijing Zhao Yan Song Yahong Cheng Tong Li Zhen Wang 
supported by the National Natural Science Foundation of China,Nos.82271327 (to ZW),82072535 (to ZW),81873768 (to ZW),and 82001253 (to TL)。
The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and ce...
关键词：apoptosis CYSTATHIONINE-Β-SYNTHASE nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide MITOCHONDRION NEUROPLASTICITY oxidative stress quinolinic acid reactive oxygen species 
Localization of the hydrogen sulfide and oxytocin systems at the depth of the sulci in a porcine model of acute subdural hematoma
《Neural Regeneration Research》2021年第12期2376-2382,共7页Oscar McCook Angelika Scheuerle Nicole Denoix Thomas Kapapa Peter Radermacher Tamara Merz 
This work was supported by a grant from the Deutsche Bundeswehr and the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)-Projektnummer 251293561-SFB 1149(to PR);a grant from the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)-Projektnummer 251293561-SFB 1149 and Ulm University-Baustein-Programm(to TM).
In the porcine model discussed in this review,the acute subdural hematoma was induced by subdural injection of autologous blood over the left parietal cortex,which led to a transient elevation of the intracerebral pre...
关键词：animal modeling brain edema CYSTATHIONINE-Β-SYNTHASE CYSTATHIONINE-Γ-LYASE gyrencephalic brain immunohistochemistry intensive care unit large animal model NEUROMONITORING oxytocin receptor 
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage被引量：2
《Neural Regeneration Research》2020年第10期1920-1930,共11页Ye Xiong Dan-Qing Xin Quan Hu Ling-Xiao Wang Jie Qiu Hong-Tao Yuan Xi-Li Chu De-Xiang Liu Gang Li Zhen Wang 
supported by the National Natural Science Foundation of China,Nos.81873768 and 81671213(to ZW),81571284 and 81874083(to GL);the Key Research and Development Foundation of Shandong Province of China,No.2017GSF218091(to ZW);the Natural Science Foundation of Shandong Province of China,No.ZR2016HM33(to DXL);the Shandong Medical and Health Science and Technology Development Plan Project of China,No.2017WS068(to QH);the Taishan Scholars of Shandong Province of China,No.ts201511093(to GL)
Hydrogen sulfide,which can be generated in the central nervous system from the sulfhydryl-containing amino acid,L-cysteine,by cystathionine-β-synthase,may exert protective effects in experimental subarachnoid hemorrh...
关键词：aminooxyacetic acid central nervous system complement deposition CYSTATHIONINE-Β-SYNTHASE early brain injury endoplasmic reticulum stress hydrogen sulfide NEUROINFLAMMATION oxidative stress subarachnoid hemorrhage 
Hydrogen sulfide intervention in cystathionine-β-synthase mutant mouse helps restore ocular homeostasis被引量：3
《International Journal of Ophthalmology(English edition)》2019年第5期754-764,共11页Akash K.George Rubens P.Homme Avisek Majumder Anwesha Laha Naira Metreveli Harpal S.SANDhu Suresh C.Tyagi Mahavir Singh 
Supported by NIH Heart, Lung, and Blood Institute (No.HL-74815);Institute of Neurological Disorders and Stroke (No.NS-084823)
AIM: To investigate the applications of hydrogen sulfide(H2 S) in eye-specific ailments in mice.METHODS: Heterozygous cystathionine-β-synthase(CBS+/-) and wild-type C57 BL/6 J(WT) mice fed with or without high methio...
关键词：blood-retinal barrier integrity endoplasmic reticulum STRESS GLUTAMATE cytotoxicity inflammation oxidative STRESS mice 
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