MYELIN

作品数：165被引量：310H指数：9
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相关机构：昆明医科大学北京协和医院重庆医科大学广州军区武汉总医院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金俄罗斯基础研究基金更多>>
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  • 期刊=Signal Transduction and Targeted Therapyx
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Inside help for brain tumors: macrophage-mediated myelin recycling promotes cell state-specific glioblastoma progression
《Signal Transduction and Targeted Therapy》2025年第1期1-2,共2页Antonio C.Pagano Zottola Thomas Daubon Varun Venkataramani 
In a recent paper published in Cell, Kloosterman et al. uncovered how lipid-laden macrophages in brain tumor called glioblastomas engage in myelin recycling, demonstrating that these cells process myelin debris into l...
关键词：MYELIN CD36 GLIOBLASTOMA 
Palmitoylation regulates myelination by modulating the ZDHHC3-Cadm4 axis in the central nervous system
《Signal Transduction and Targeted Therapy》2024年第10期4683-4699,共17页Yanli Chang Jiangli Zhu Xiaopeng Li Yi Deng Birou Lai Yidan Ma Jia Tong Huicong Liu Juanjuan Li Chenyu Yang Qiao Chen Chengbiao Lu Yinming Liang Shiqian Qi Xiaoning Wang Eryan Kong 
National Natural Science Foundation of China(Grant No.32100776 to Y.L.C.,and No.32371309 to E.Y.K.);The genetic modification of cell lines and mouse were supported by 111 program(D20036).
The downregulation of Cadm4 (Cell adhesion molecular 4) is a prominent feature in demyelination diseases, yet, the underlying molecular mechanism remains elusive. Here, we reveal that Cadm4 undergoes specific palmitoy...
关键词：MYELIN SYSTEM TOGETHER 
Rough operators: sphingomyelinase inhibitors spike NK cells to kill cancer
《Signal Transduction and Targeted Therapy》2023年第9期3892-3893,共2页Mattias Carlsten Yenan T.Bryceson 
This work was supported by grants from the Swedish Cancer Foundation and Swedish Research Council(to M.C.and Y.T.B.);the Knut and Alice Wallenberg Fellows program(to Y.T.B.).
In a recent study published in Nature Immunology,Zheng et al.discovered that intratumoral NK cells were smooth and rounded as opposed to the typical vili-rich,rougher surface of normal NK cells.1 This phenotype was li...
关键词：MYELIN IMPAIRED CANCER 
Caspase-7 and acid sphingomyelinase:partner repairmans of gasdermin and perforin pores
《Signal Transduction and Targeted Therapy》2022年第9期3172-3173,共2页Ke Jin Guofang Shen 
This work was supported by the Chinese National Natural Science Funds(81902947).
Recently,a work published in Nature by Kengo Nozaki et al.revealed a novel mechanism for plasma membrane pores'repair mediated by caspase-7.In this work,they found caspase-7 facilitated Intestinal epithelial cell(IEC)...
关键词：MYELIN al. pores 
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