COPTISINE

作品数：4被引量：3H指数：1
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相关领域：医药卫生理学更多>>
相关机构：中南民族大学更多>>
相关期刊：《Traditional Medicine Research》《Journal of Environmental Sciences》《Medicinal Plant》《Acta Pharmacologica Sinica》更多>>
相关基金：国家教育部博士点基金国家自然科学基金更多>>
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Integration of network pharmacology with experimental verification reveals the hypoglycemic mechanism of coptisine in Jinqi Jiangtang tablets:inhibition of the FoxO1 signaling pathway and hepatic gluconeogenesis
《Traditional Medicine Research》2023年第3期51-61,共11页Hang Gong Yu-Cai Chen Jia-Qi Xie Yi-Hong Li Li-Dan Cui Hong-Tao Jin Can Wang 
the Fundamental Research Funds for the Central Universities(grant number:2021-JYB-XJSJJ-003);the Open Project of State Key Laboratory of Bioactive Substance and Function of Natural Medicines(grant number:GTZK202108);Chinese Society of Toxicology(grant number:CST2021CT101);Discipline Construction Project of Peking Union Medical College(grant number:201920200801).
Background:Jinqi Jiangtang tablets(JQJT)have been approved for the treatment of type 2 diabetes mellitus(T2DM)in China for many years.Exploring the effective substances and mechanisms of JQJT is important for its clin...
关键词：Jinqi Jiangtang tablets FOXO1 GLUCONEOGENESIS type 2 diabetes mellitus network pharmacology 
Simultaneous Determination of Effective Components of Gegen Qinlian Tablets by HPLC
《Medicinal Plant》2020年第1期24-28,36,共6页Lili LI Yifeng LU Xueyan ZHU 
[Objectives]To establish a HPLC method for the simultaneous determination of 14 characteristic components in Gegen Qinlian tablets and the content of Gegen Qinlian tablets in 11 manufacturers.[Methods]A Inertsil ODS-3...
关键词：Gegen Qinlian tablets Content determination High performance liquid chromatography Puerarin DAIDZIN Liquiritin Baicalin WOGONOSIDE Epierberine JATRORRHIZINE HYDROCHLORIDE COPTISINE Daidzein PALMATINE HYDROCHLORIDE Ammonium glycyrrhizinate Berberine HYDROCHLORIDE Baicalein Wogonin 
Inhibitory effects of phytochemicals on metabolic capabilities of.CYP2D6＊1 and CYP2D6＊10 using cell-based models in vitro
《Acta Pharmacologica Sinica》2014年第5期685-696,共12页Qiang QU Jian QU Lu HAN Min ZHAN Lan-xiang WU Yi-wen ZHANG Wei ZHANG Hong-hao ZHOU 
This work was supported by the State Scholarship Fund from China Scholarship Council （No 201206370103）, the National Natural Science Foundation of China （No 81273595, 81072706, and 84402511）, the Scientific Foundation of Hunan （No 11K073 and 10JJ4020）, the ＂863＂ Project （No 2012AA02A518）, NCET- 10-0843 and the Research Innovation Foundation of Graduate Student in Hunan province, China （CX2011B056）. We are grateful to Dr Curtis D KLAASSEN and Helen RENAUD who provided language help.
Aim： Herbal products have been widely used, and the safety of herb-drug interactions has aroused intensive concerns. This study aimed to investigate the effects of phytochemicals on the catalytic activities of human ...
关键词：CYP2D6 drug interaction herbal medicine COPTISINE BILOBALIDE schizandrin LUTEOLIN PUERARIN 
Determination of paraquat in water samples using a sensitive fluorescent probe titration method被引量：3
《Journal of Environmental Sciences》2013年第6期1245-1251,共7页Feihu Yao Hailong Liu Guangquan Wang Liming Du Xiaofen Yin Yunlong Fu 
supported by the National Natural ScienceFoundation of China (No. 21171110);the Research Fund for the Doctoral Program of Higher Education of China (No. 20091404110001)
Paraquat （PQ）, a nonselective herbicide, is non-fluorescent in aqueous solutions. Thus, its determination through direct fluorescent methods is not feasible. The supramolecular inclusion interaction of PQ with cucur...
关键词：PARAQUAT COPTISINE uril supramolecular interaction fluorescent probe titration 
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