supported by the National Natural Science Foundation of China(Nos.81930122 and U20A20361);the National Key Research and Development Project of China(No.2021YFC2102101).
Conjugate vaccines represent one of the most effective means for controlling the occurrence of bacterial diseases.Although nanotechnology has been greatly applied in the field of vaccines,it is seldom used for conjuga...
Aim: Shigella flexneri (S. flexneri) is a gram-negative enterobacterium responsible for severe intestinal end systemic infection in humans. The bacteria can reach the liver due to degeneration of the colonic epitheliu...
supported by the State“973”Key Basic Research Program(Grant No.G1999054103);the State“863”High-Tech Project(Grant No.Z19-02-05-01);Beijing Innovation Engineering(Grant No.955020700);the North China Pharmaceutical Corporation(NCPC)
Comparative genome analysis is performed between Shigella flexneri 2a strain 301 and its close relatives, the nonpathogenic E. Coli K-12 strain MG1655. Result shows that there are 136 DNA segments whose size is larger...