supported by the National Natural Science Foundation of China(82271862 and 81873418 to YK,82171730 to PX,81970484 to QC);the Zhejiang Provincial Ten Thousand Program for Leading Talents of Science and Technology Innovation(2021R52015 to YK);the Natural Science Foundation of Zhejiang Province(LY20H160032 to PX,LQ21H090064 to TP).
Mannose is a naturally occurring sugar widely consumed in the daily diet;however,mechanistic insights into how mannose metabolism affects intestinal inflammation remain lacking.Herein,we reported that mannose suppleme...
Background: Rheumatoid arthritis (RA) is a common autoimmune disease in which a combination of risk alleles from different susceptibility genes predisposes the patients to develop clinical symptoms following exposure ...
Shenzhen Science and Technology Project(Medical and Health)No.200703136.
Objective:To study the relationship between serum levels of IL-4,IL-8,TNF-alpha,T cell subsets and prognosis in patients with psoriasis vulgaris.Methods:A total of 120 patients with psoriasis vulgaris who were treated...
Objective:To explore the changes of serum TNF-alpha, IL-2 and IL-13 in patients with rheumatoid arthritis (RA).Methods: A total of 60 patients with rheumatoid arthritis admitted to our hospital from December 2016 to D...
The G-CSF is used as a therapeutic drug of the febrile neutropenia in lung cancer chemotherapy, however, there were few reports that showed the effects of combination effects of G-CSF and anticancer drugs against lung...
supported by the special plan of maternal and child health molecular genetic medicine of Maternal and Child Health Care Center in Chinese Center for Discase Control and Prevention(Grant No.FY-ZX-ZD-0059)
Objective: To study the preventive and therapeutic effect of N-Acetyl-L-cysteine on infection-associated preterm labor in mice. Methods: A total of 66 C57BL/6 inbred strain pregnant mice were selected and randomly div...
Aim: Shigella flexneri (S. flexneri) is a gram-negative enterobacterium responsible for severe intestinal end systemic infection in humans. The bacteria can reach the liver due to degeneration of the colonic epitheliu...
Ami To investigate PGE2 and TNF-alpha signaling pathway involving in the maturation and activation of bone marrow dendritic cells (DCs) and the effect of CP-25. Method Bone marrow DCs were isolated and stim- ulated ...
supported by National Natural Science Foundation(No.81260315);Foundation of the Education Department of Guangxi Province,China(No.201010LX375);the Foundation of the Nature Science Fund,Guangxi Province,China(No.2012GXNSFBA053121)
Objective: Previous studies have investigated the role of cytotoxic T-lymphocyte antigen-4 (CTLA-4) and tumor necrosis factor-alpha (TNF-a) in carcinogenesis of osteosarcoma, but their results were inconsistent. ...
Financial support has been obtained from the Faculty of Medicine,Umea University,and the J.C.Kempe and Seth M.Kempe Memorial Foundations,Ornskoldsvik
Using a rabbit model leading to myositis in response to exercise-induced muscle overuse, we have previously observed that TNF-alpha is involved in the exercised muscle in early developing myositis as well as both ipsi...