PLASMID-MEDIATED

作品数：10被引量：45H指数：5
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相关领域：医药卫生更多>>
相关作者：茆海丰王春梅更多>>
相关机构：连云港市第一人民医院更多>>
相关期刊：《Engineering》《Science in One Health》《Journal of Environmental Sciences》《Zoological Research》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Emergence of plasmid-mediated tigecycline resistance tet(X4)gene in Enterobacterales isolated from wild animals in captivity
《Science in One Health》2024年第1期134-139,共6页Lei Lei Panfeng Xiong Zelin Yan Yanyan Zhang Yuchen Wu Gongxiang Chen Houhui Song Rong Zhang 
supported by the National Key Research and Development Program of China[grant number:2022YFD1800403];National Natural Science Foundation of China[grant number:82072341].
Background:Over the past few decades,antimicrobial resistance(AMR)has emerged as a global health challenge in human and veterinary medicine.Research on AMR genes in captive wild animals has increased.However,the prese...
关键词：Wild animal tet(X4) Enterobacterales ENTEROTOXIN Tigecycline resistance Epidemiology 
Effect of sulfamethazine on the horizontal transfer of plasmid-mediated antibiotic resistance genes and its mechanism of action被引量：1
《Journal of Environmental Sciences》2023年第5期399-409,共11页Xiaojing Yan Wenwen Liu Shengfang Wen Lanjun Wang Lusheng Zhu Jun Wang Young Mo Kim Jinhua Wang 
supported by the National Natural Science Foundation of China(No.41671320);the Natural Science Foundation of Shandong Province,China(No.ZR2016JL029)and the Special Funds of Taishan Scholar of Shandong Province,China.
As a new type of environmental pollutant,antibiotic resistance genes(ARGs)pose a huge challenge to global health.Horizontal gene transfer(HGT)represents an important route for the spread of ARGs.The widespread use of ...
关键词：SULFAMETHAZINE PLASMID Antibiotic resistance gene Conjugation transfer 
Genomic and Phenotypic Diversity of Carbapenemase-Producing Enterobacteriaceae Isolates from Bacteremia in China: A Multicenter Epidemiological, Microbiological, and Genetic Study被引量：2
《Engineering》2022年第5期90-100,共11页Beiwen Zheng Hao Xu Lihua Guo Xiao Yu Jinru Ji Chaoqun Ying Yunbo Chen Ping Shen Huiming Han Chen Huang Shuntian Zhang Tao Lv Yonghong Xiao 
the financial support of the National Key Research and Development Program of China (2017YFC1200203 and 2016YFD0501105);the Mega-projects of Science Research of China (2018ZX10733402-004 and 2018ZX10712001-005);the National Natural Science Foundation of China (81741098 and 81711530049);the Zhejiang Provincial Key Research and Development Program (2015C03032);the Zhejiang Provincial Natural Science Foundation of China (LY17H190003)
Carbapenemase-producing Enterobacteriaceae(CPE) isolates are recognized as one of the most severe threats to public health. However, the population structure and genetic characteristics of CPE isolates among bloodstre...
关键词：CARBAPENEMASE Carbapenemase-producing ENTEROBACTERIACEAE PLASMID-MEDIATED China Extended-spectrum b-lactamase 
Detection of Plasmid-Mediated Tigecycline Resistance Gene tet(X4) in a Salmonella enterica Serovar Llandoff Isolate被引量：2
《Infectious Microbes & Diseases》2021年第4期198-204,共7页Yanan Wang Fei Liu Xuebin Xu Hua Huang Na Lyu Sufang Ma Luping Chen Mengyu Mao Yongfei Hu Xiaofeng Song Jing Li Yuanlong Pan Aiping Wang Gaiping Zhang Baoli Zhu George F.Gao 
This study was supported by the Major Program of National Natural Science Foundation of China(81991534);the Major State Basic Research Development Program(2018YFC1603803);the National Key Research and Development Program of China(grant number:2018YFC1603900).
The emergence and spread of plasmid-mediated tigecycline resistance genes have attracted extensive attention worldwide.We investigated the distribution of mobile tigecycline resistance genes in Salmonella genomes gene...
关键词：Salmonella enterica serovar Llandoff tet(X4) tigecycline resistance 
Co-selection may explain the unexpectedly high prevalence of plasmid-mediated colistin resistance gene mcr-1 in a Chinese broiler farm被引量：5
《Zoological Research》2020年第5期569-575,共7页Yu-Ping Cao Qing-Qing Lin Wan-Yun He Jing Wang Meng-Ying Yi Lu-Chao Lv Jun Yang Jian-Hua Liu Jian-Ying Guo 
supported in part by the National Natural Science Foundation of China(31830099,31902322);International Science and Technology Cooperation Project of Xinjiang Production and Construction Corps(XPCC)(2019BC004);Guangdong Special Support Program Innovation Team(2019BT02N054);Innovation Team Project of Guangdong University(2019KCXTD001)。
DEAR EDITOR,The rise of the plasmid-encoded colistin resistance gene mcr-1 is a major concern globally.Here,during a routine surveillance,an unexpectedly high prevalence of Escherichia coli with reduced susceptibility...
关键词：globally ROUTINE EXPLAIN 
Acquired Resistance to Colistin via Chromosomal And Plasmid-Mediated Mechanisms in Klebsiella pneumoniae
《Infectious Microbes & Diseases》2019年第1期10-19,共10页Björn Berglund 
supported by the Swedish Research Council Formas(2016-00640);the Swedish Foundation for International Cooperation in Research and Higher Education(STINT)(CH2016-6707).
The increasing prevalence of resistance to the last-resort antibiotics carbapenems is leading to increasing difficulties in treating infections caused by multidrug-resistant carbapenem-resistant Gram-negative bacteria...
关键词：Klebsiella pneumoniae COLISTIN MUTATION antibiotic resistance plasmid mcr-1 
Prevalence and characterization of plasmid-mediated blaESBL with their genetic environment in Escherichia coli and Klebsiella pneumoniae in patients with pneumonia被引量：13
《Chinese Medical Journal》2012年第5期894-900,共7页WANG Xiao-rong CHEN Ji-chao KANG Yu JIANG Ning AN Shu-chang GAO Zhan-cheng 
Background The extended spectrum 13-1actamase （ESBL）-producing Escherichia coil （E. coh） and Klebsiella pneumoniae （K. pneumoniae） are the major pathogens causing pneumonia and have a significant impact on the c...
关键词：mechanism of resistance promoter CTX-M SHV  gene silence plasmid incompatibility group 
Detection of plasmid-mediated IMP-1 metallo-β-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate被引量：7
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2009年第5期348-354,共7页Li-rong CHEN Hong-wei ZHOU Jia-chang CAI Rong ZHANG Gong-xiang CHEN 
Objective： To investigate the mechanism of carbapenem resistance and the occurrence ofplasmid-mediated quinolone resistance determinants qnr and aac（6＇）-Ib-cr in a clinical isolate of Enterobacter cloacae. Methods...
关键词：Antibiotic resistance Carbapenem ENTEROBACTERIACEAE Outer membrane proteins （OMPs） 
Transconjugation and genotyping of the plasmid-mediated AmpC β-lactamase and extended-spectrum β-lactamase genes in Klebsiella pneumoniae被引量：9
《Chinese Medical Journal》2009年第9期1092-1096,共5页SHI Wei-feng ZHOU Jun QIN Jian-ping 
Bsckgroud AmpC β-lactamases and extended-spectrum β-lactamases （ESBLs） are becoming predominant causes of resistance to third and forth-generation cephalosporins in Klebsiella pneumoniae （K. pneumoniae）. It is v...
关键词：Klebsiella pneumoniae PLASMID transconjugation Β-LACTAMASE 
Coexistence of qnrB4 and qnrS1 in a clinical strain of Klebsiella pneumoniae被引量：6
《Acta Pharmacologica Sinica》2008年第3期320-324,共5页Fu-pin HU Xiao-gang XU De-mei ZHU Ming-gui WANG 
This work was supported by grants from the National Basic Research Program of China, the Ministry of Science and Technology, China （No_ 2005CB0523101）, the National Natural Science Foundation of China （No_ 30440061 and 30572229）, the Science and Technology Commission of Shanghai Municipality （No_ 06XD14030）, and the Shanghai Municipal Health Bureau （No_ LJ06052）.Acknowledgements We thank George A JACOBY and David C HOOPER for providing reference strains E coli J53Az^R, E coli V517, and E coli R27. We are also grateful to George A JACOBY for critically reviewing the manuscript.
Aim： To identify the location and the relationship, and to analyze the genetic background of 2 plasmid-mediated quinolone resistance genes, qnrB4 and qnrS1, carried by a clinical strain of Klebsiella pneumoniae （Kpn...
关键词：QUINOLONES PLASMID-MEDIATED resistance qnrB  qnrS 
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