supported by the National Key Research and Development Program of China(2021YFF1200602).
The global prevalence rate for congenital hydrocephalus(CH)is approximately one out of every five hundred births with multifaceted predisposing factors at play.Genetic influences stand as a major contributor to CH pat...
Single ventricle is an uncommon congenital cardiac pathology with high mortality at early ages. However, due to new strategies and timely surgical treatment, it is increasingly seen in adults, which has increased the ...
supported by grants from the National Natural Science Foundation of China(82088101 and 81930013 to Y.-H.C.,82122007 and 82070271 to D.L.);the National Key R&D program of China(2019YFA0801501 to Y.-H.C.);the Key Research Center Construction Project of Shanghai(2022ZZ01008 to Y.-H.C.);the Shuguang Program of Shanghai Education Development Foundation and Shanghai Municipal Education Commission(22SG19443 to D.L.);the Top-level Clinical Discipline Project of Shanghai Pudong District(PWYgf2021-01);the Shanghai Key Clinical Specialty Project(shslczdzk06202);the Research Unit of Origin and Regulation of Heart Rhythm,Chinese Academy of Medical Sciences(2019RU045);the National Key Clinical Specialty and the Fundamental Research Funds for the Central Universities to Y.-H.C.
Physiologically,the atria contract first,followed by the ventricles,which is the prerequisite for normal blood circulation.The above phenomenon of atrioventricular sequential contraction results from the characteristi...
supported by grants from the National Natural Science Foundation of China(81930008,81900792);the Natural Science Foundation of Chongqing(2023NSCQ-MSX2101);the National Key R&D Program of China(2018YFC1312700);the Program of Innovative Research Team by the National Natural Science Foundation(81721001);the Program for Changjiang Scholars and Innovative Research Team in University;IRT1216.
Stimulation of adult cardiomyocyte proliferation is a promising strategy for treating myocardial infarction(MI).Earlier studies have shown increased CCL2 levels in plasma and cardiac tissue both in MI patients and mou...
supported by Laoshan Laboratory(LSKJ202203204);the National Natural Science Foundation of China(31970506 and 32170541 to LZ;31970475 and 32170832 to YS);the Fundamental Research Funds for Central Universities,China(202012004 to LZ).
The evolution of a two-chambered heart,with an atrium and a ventricle,has improved heart function in both deuterostomes(vertebrates)and some protostomes(invertebrates).Although studies have examined the unique structu...
Background: EVD is a common procedure done in neurosurgery and the residents should master it and this is what exactly means that it should be simple, safe, fast and accurate. EVD can be done through many entry points...
supported by National Natural Science Foundation of China[81970444];The Fundamental Research Funds for the Central Universities[2019PT350005];Beijing Municipal Science and Technology Project[Z201100005420030];National high level talents special support plan[2020-RSW02];CAMS Innovation Fund for Medical Sciences[2021-I2M-1-065,2021-I2M-1-058];Sanming Project of Medicine in Shenzhen[SZSM202011013];Natural Science Fund for Distinguished Young Scholars of Tianjin[21JCJQJC00020].
Ventricular septal defect(VSD)is one of the commonest congenital heart diseases(CHDs).Current occluders for VSD treatment are mainly made of nitinol,which has the risk of nickel allergy,persistent myocardial abrasion ...
supported by the National Key Research and Development Program,China(2018YFD0900406);the National Natural Science Foundation,China(31802291);the Natural Science Foundation of Hunan Province(2021JJ40342)。
Recently,cilia defects have been proposed to contribute to scoliosis.Here,we demonstrate that coiled-coil domain-containing 57(Ccdc57)plays an essential role in straightening the body axis of zebrafish by regulating c...
Retraction:Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children https://doi.org/10.4103/1673-5374.346552 The Editors of Neural Regeneration Resea...
supported by the Development and Research Fund of Topical Medicine(2020-2-2065);the International Key Research and Development Program of Ministry of Science and Technology(2020 YFC2008105)。
Aortic annulus calcification(AC)and mitral AC are common in patients with cardiac valvular disease.[1]Procedures to resect or debride aortic AC and mitral AC may lead to cerebral emboli,heart failure,arrhythmia,corona...