STILBENE

作品数：51被引量：254H指数：7
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相关领域：理学医药卫生更多>>
相关作者：朱亚波翁建全刘幸海谭成侠肖凯更多>>
相关机构：浙江工业大学中国科学院广东药科大学浙江农林大学更多>>
相关期刊：《Journal of Pharmaceutical Analysis》《Chinese Journal of Chemical Physics》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>
相关基金：国家自然科学基金国家科技支撑计划中国科学院科研项目中国博士后科学基金更多>>
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The near-complete genome assembly of Reynoutria multiflora reveals the genetic basis of stilbenes and anthraquinones biosynthesis
《Journal of Systematics and Evolution》2024年第6期1085-1102,共18页Qiang He Yuqing Miao Xinyuan Zheng Yaru Wang Yitao Wang Zheng Jia Hongyu Zhang Yu Wang Yao Xiao Cailian Du Wei Li Longsheng Xing Huilong Du 
supported by the National Natural Science Foundation of China(grant 32100500);Natural Science Foundation of Hebei Province(grant C2021201048);the Interdisciplinary Research Program of Natural Science of Hebei University(513201422004).
Reynoutria multiflora is a widely used medicinal plant in China.Its medicinal compounds are mainly stilbenes and anthraquinones which possess important pharmacological activities in anti-aging,anti-inflammatory and an...
关键词：comparative genomics genome assembly Reynoutria multiflora stilbene and anthraquinone biosynthesis 
Geographic variation in secondary metabolites contents and their relationship with soil mineral elements in Pleuropterus multiflorum Thunb.from different regions
《Science of Traditional Chinese Medicine》2024年第3期214-223,共10页Yaling Yang Siman Wang Ruibin Bai Feng Xiong Yan Jin Hanwei Liu ZiyiWang Chengyuan Yang Yi Yu Apu Chowdhury Chuanzhi Kang Jian Yang Lanping Guo 
financially supported by the scientific and technological innovation project of the China Academy of Chinese Medical Sciences(Grant Nos.CI2021A03905,CI2021A04011,CI2021A04005);Quality and Technical Service Platform for Traditional Chinese Medicine Whole Industry Chain(Grant No.2022-230-221);China Agricultural Research SystemofMOF andMARA(CARS-21);the Key Project at Central Government Level:the ability establishment of sustainable use for valuable Chinese medicine resources(Grant No.2060302).
Background:Pleuropterus multiflorum Thunb.cv.“Heshouwu”(HSW)has been used as a classical material for both medicine and food in China for millennia.Recently,the cultivation region of HSW has shifted from Guangdong t...
关键词：Pleuropterus multiflorum Thunb. Geographical difference Soil mineral element UPLC-QQQ-MS Stilbene glycosides ANTHRAQUINONES 
The first chromosome-level Fallopia multiflora genome assembly provides insights into stilbene biosynthesis
《Horticulture Research》2023年第5期112-125,共14页Yujiao Zhao Zhengyang Yang Zhongren Zhang Minzhen Yin Shanshan Chu Zhenzhen Tong Yuejian Qin Liangping Zha Qingying Fang Yuan Yuan Luqi Huang Huasheng Peng 
This study was funded by the National Natural Science Foundation of China(No.81973432);the Major Increase and Reduction Project at the Central Level(No.2060302);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202005);CAMS Innovation Fund for Medical Sciences(2019-I2M-5-065).
Fallopia multiflora(Thunb.)Harald,a vine belonging to the Polygonaceae family,is used in traditional medicine.The stilbenes contained in it have significant pharmacological activities in anti-oxidation and anti-aging....
关键词：STILBENE INSIGHT CATALYSIS 
The effect and mechanism of stilbene glycosides on improving neuronal injury in Alzheimer's disease rats by regulating ASK/MKK7/JNK pathway
《Journal of Hainan Medical University》2023年第21期1-6,共6页LI Yue KANG Bi-qian HE Xiao-xuan HU Rui XIAO Zhen LUO Chen-liang WU Gui-you HUANG Zhong-shi 
National Natural Science Foundation of China (81860709);Project of Baise City Regional Multiple Development Joint Special Plan[Bai Zi (2022)41-39]。
Objective:To investigate the mechanism of action of tetrahydroxy stilbene glycosides(TSG)in ameliorating neuronal damage in Alzheimer's disease rats by regulating MKK7 and JNK kinases.Methods:A total of 24-month-old 4...
关键词：Nervous system Alzheimer’s disease Stilbene glycoside MKK7 JNK 
Third-Order Nonlinear Optical Responses of Bis(15-crown-5)-stilbenes Binding to One-or Two-Alkali Metal Cation(Li^(+),Na^(+)and K^(+))
《Chinese Journal of Chemical Physics》2023年第5期601-612,I0002,共13页Hai-Ling Yu Tong Zhang Tian-Liang Ma Bo Hong Zhi-Qiang Cheng 
surported by the Jilin Province Science and Technology Development Project(No.20220203017SF);Industrialization Project of the 13th Five-Year"Education Department of Jilin Province(No.JJKH20200334KJ);the National Natural Sci-ence Foundation of China(No.11704143).
Bis(15-crown-5)-stilbenes containing crown ether parts have been widely used in a variety of chemical applications,such as cation detectors,because of their ability to selectively bind to alkali metal cations,Bis(15-c...
关键词：Bis(crown)-stilbene Cation detector Metal cation Quantum chemistry Sec-ond hyperpolarizability 
Hypoglycemic effects of naturally processed Polygonum multiflorum extract in KK CgAy/J mice and its mechanism of action被引量：1
《Food Science and Human Wellness》2022年第5期1177-1182,共6页Wenping Tang Jianfeng Zhan Shiming Li Yue Liu Chi-Tang Ho 
supported by Hubei Science and Technology Plan key Project,Hubei Province,China(2019ABA100)。
In 2021,there are approximately 537 million adults ageing 20-79 years affected by diabetes worldwide and the number is rising rapidly,hence it is important to manage and control diabetes mellitus and its associated co...
关键词：DIABETES Stilbene glycoside Polygonum multiflorum Hypoglycemic activity Homeostatic model assessment 
Effect of TSG on tau phosphorylation via GSK-3βpathway
《Journal of Hainan Medical University》2022年第14期16-23,共8页Wan-Ying Meng Chao-Yu Liu Xiao-Yan Xia Yan-Bing Li Zhen-Zhong Li Xiao-Ying Zhu Yan-Hua Liao Zhong-Shi Huang 
Guangxi Natural Science Foundation(No.2018GXNSFAA294153)。
Objective:To observe how TSG interferes with Tau phosphorylation in Aβ25-35 induced dementia model via GSK-3βpathway.Methods:Thirty-six male SD rats aged 24 months were randomly divided into control group,sham group...
关键词：Tetrahydroxy stilbene glycoside Alzheimer's disease GSK-3Β PI3K PKC PKB PKA 
Mutations of the brpR and brpS genes affect biofilm formation in Staphylococcus aureus
《World Journal of Clinical Infectious Diseases》2022年第1期20-32,共13页Allison Zank Lillian Schulte Xavier Brandon Lauren Carstensen Amy Wescott William R Schwan 
BACKGROUND In the United States,Staphylococcus aureus(S.aureus)kills tens of thousands of individuals each year and the formation of a biofilm contributes to lethality.Biofilm-associated infections are hard to treat o...
关键词：BIOFILM Two-component system STILBENE Staphylococcus aureus Late-stage competence SK-03-92 
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver被引量：3
《Acta Pharmacologica Sinica》2020年第11期1433-1445,共13页Ya-ru Xue Sheng Yao Qian Liu Zhao-liang Peng Qiang-qiang Deng—Bo Liu Zheng-hua Ma Le Wangf Hu Zhou Yang Ye Guo-yu Pan 
supported by the‘Organ Reconstruction and Manufacturing’Strategic Priority Research Program of the Chinese Academy of Sciences[grant number XDA16020205];the National Science Foundation of China[grant number 81872927];the International Partnership Program of Chinese Academy of Sciences[grant number 153631KYSB20160004];the Independent Deployment Program of the Institute of Pharmaceutical Innovation of the Chinese Academy of Sciences[grant number CASIMM0120184005];the China Postdoctoral Science Foundation[grant number 2019M651623].
In general,anti-inflammatory treatment is considered for multiple liver diseases despite the etiology.But current drugs for alleviating liver inflammation have defects,making it necessary to develop more potent and sa...
关键词：gigantol Chinese traditional medicine liver injury oxidative stress INFLAMMATION label-free proteomic complement and coagulation cascades terminal complement complex 
天然stilbene导向的取代苯乙烯基噻唑化合物的合成和生物活性被引量：2
《有机化学》2020年第4期1055-1061,共7页章俊辉 朱亚波 翁建全 余茜 袁静 陈杰 
浙江省自然科学基金(No.LY17C140003)资助项目.
为了寻找新型结构的药物先导化合物,基于天然stilbenes骨架结构,将含氟苯基噻唑环结构与其相杂合,设计合成了一系列新型取代苯乙烯基噻唑类化合物.所有目标化合物结构均经1H NMR、13C NMR和ESI-HRMS表征确证.离体真菌抑制活性结果表明,...
关键词：二苯乙烯 苯乙烯基噻唑 合成 生物活性 
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