Supported by Beijing Municipal Science and Technology Commission(No.Z151100004015217)。
AIM:To observe changes in the content of matrix metalloproteinases(MMPs)in the corneal stroma after corneal cross-linking(CXL)in rabbits,and further explore the corneal pathophysiological process after CXL.METHODS:For...
AIM:To compare the safety and efficacy of conventional versus accelerated(9 mW/cm^2)corneal collagen crosslinking(CXL)in progressive keratoconus at the 2-year follow-up.METHODS:In this prospective study,consecutive pr...
AIM: To assess the effect of photoactivated chromophore for keratitis crosslinking(PACK-CXL) in case of severe keratitis with melting on the electrophysiological function of the retina and the optic nerve.METHODS: The...
Supported by the National Natural Science Foundation of China (No.81660169);the Science and Technology Foundation of Zunyi [No.(2014)94]
AIM: To evaluate the biomechanical stability of the corneal scar treating with riboflavin and ultraviolet A(UVA). METHODS: Totally 86 New Zeal rabbits were divided into control group(group A, n=8) and trauma groups [g...
Supported by Beijing Municipal Science and Technology Commission(No.Z151100004015217)
Corneal cross-linking(CXL) is a noninvasive therapeutic procedure for keratoconus that is aimed at improving corneal biomechanical properties by induction of covalent cross-links between stromal proteins. It is acco...
Supported by Beijing Municipal Science and Technology Commission(No.Z151100004015217)
AIM:To report the clinical results of iontophoresis-assisted epithelium-on corneal crosslinking(I-CXL) using 0.1% riboflavin in distilled water for progressive keratoconus. METHODS:In this prospective clinical stu...
Supported by an internal grant from New Vision Inc.;Talent-Xiamen(XM-200)Program(Xiamen Science&Technology Bureau,China)
AIM: To analyze the efficacy of ultraviolet (UV) light initiating corneal cross-linking (CXL). METHODS: The time-dependent absorption of UV light due to the depletion of the initiator (riboflavin) was calculated. The ...
Dear Sir,UVA/riboflavin cross-linking (CXL) has been used clinically applied for the treatment of keratoconus and corneal edema via enhancement of corneal stiffness The safety of the corneal endothelium is of prime...
AIM: To evaluate the enrichment of riboflavin in the corneal stroma after intracameral injection to research the barrier ability of the corneal endothelium to riboflavin in vivo.METHODS: The right eyes of 30 New Zeala...
Supported by Jiangsu Province's Key Provincial Talents Program(RC2011104)
Keratoconus is a condition characterized by biomechanical instability of the cornea, presenting in a progressive, asymmetric and bilateral way. Corneal collagen crosslinking(CXL) with riboflavin and Ultraviolet-A(UVA)...