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Relationship between Helicobacter pylori infection and programmed death-ligand 1 in gastric cancer:A meta-analysis: 《World Journal of Clinical Oncology》2025年第4期280-290,共11页Hong-Chang Yang Cheng-Feng Fu Li-Jun Qiao Gen-He Long Li-Fen Yang Biao Yao; BACKGROUND Gastric cancer(GC)is one of the most common malignancies worldwide,and Helicobacter pylori(HP)infection is a well-established risk factor for its development.Programmed death-ligand 1(PD-L1)expression is a ...; 关键词：Helicobacter pylori Gastric cancer Programmed cell death protein 1/programmed death-ligand 1 Immune checkpoint blockade therapy PATHOGENESIS

Immune checkpoint blockade for cancer therapy: current progress and perspectives: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2025年第3期203-226,共24页Hongying YE Wejie LIAO Jiongli PAN Yin SHI Qingqing WANG; supported by the National Key Research and Development Program of China(No.2022YFE0102100);the National Natural Science Foundation of China(Nos.U22A20307 and 81930041)。; Dysfunction of anti-tumor immune responses is crucial for cancer progression. Immune checkpoint blockade(ICB), which can potentiate T cell responses, is an effective strategy for the normalization of host anti-tumor i...; 关键词：Immune checkpoint blockade Cancer immunotherapy Tumor immune evasion Immune normalization

A lipid/PLGA nanocomplex to reshape tumor immune microenvironment for colon cancer therapy: 《Regenerative Biomaterials》2025年第1期20-31,共12页Nan Zhang Qiqi Sun Junhua Li Jing Li Lei Tang Quan Zhao Yuji Pu Gaofeng Liang Bin He Wenxia Gao Jianlin Chen; supported by the National Natural Science Foundation of China[52073216 and 51773130].; Immune checkpoint blockade therapy provides a new strategy for tumor treatment;however,the insufficient infiltration of cytotoxic T cells and immunosuppression in tumor microenvironment lead to unsatisfied effects.Her...; 关键词：lipid/PLGA nanocomplex immune checkpoint blockade photodynamic therapy IDO inhibition colon cancer

THREADS Check out social media's new kid on the block!: 《空中英语教室(中级版)》2025年第1期14-15,49,56,共4页David Morton; Looking for something new to try in the social media world?If so,Meta's Threads just might be the app for you.This app has over 190 million users and some innovative features.But before you jump on the bandwagon,let's...; 关键词：app media CLOSER

CHILL OUT,CHECK IN: 《Beijing Review》2025年第3期16-17,共2页Tao Xing; After scrolling through numerous social media posts documenting ice and snow tourism activities,Sun Qi and her friends couldn't wait to visit the frosty city of Harbin in northeast China’s Heilongjiang Province.After...; 关键词：TRAVEL NORTHEAST TOURISM

Targeting the epigenome to reinvigorate T cells for cancer immunotherapy: 《Military Medical Research》2024年第6期863-886,共24页Dian Xiong Lu Zhang Zhi-Jun Sun; supported by the National Natural Science Foundation of China(82273202,82370948,82072996,82170941);the Fundamental Research Funds for the Central Universities(2042022dx0003);the Hubei Province International Science and Technology Cooperation Project(2021EHB027);the National Key Research and Development Program(2022YFC2504200).; Cancer immunotherapy using immune-checkpoint inhibitors(ICIs)has revolutionized the field of cancer treatment;however,ICI efficacy is constrained by progressive dysfunction of CD8+tumor-infiltrating lymphocytes(TILs),...; 关键词：Epigenetic therapy Immune checkpoint blockade Combination therapy T cell exhaustion Immune macroenvironment Spatial immune contexture Immunometabolism Cancer microbiome

A Novel Asymmetric Check Microvalve for Suppressing Flow Boiling Instability in Microchannels: 《Journal of Thermal Science》2024年第6期2336-2347,共12页ZHOU Fan ZHAO Yang YIN Ershuai HU Dinghua LI Qiang; support from the National Natural Science Foundation of China with Grant No.52276070;the Fundamental Research Funds for the Central Universities with Grant No.30922010903。; Flow boiling in microchannels has attracted wide attention due to its excellent heat transfer capability,but flow boiling instability is a huge challenge limiting its application.Instability can lead to a series of pr...; 关键词：flow boiling instability topology optimization MICROCHANNEL bubble dynamics

Operation Strategy of Rail Transit Green Energy System Considering Uncertainty Risk of Photovoltaic Power Output: 《Journal of Modern Power Systems and Clean Energy》2024年第6期1859-1868,共10页Yanbo Chen Haoxin Tian Guodong Zheng Yuxiang Liu Maja Grbic; This work was supported in part by the National Key Research and Development Program of China(No.2021YFB2601502);in part by the Beijing Natural Science Foundation Program(No.L221002).; The integration of photovoltaic power generation is a new development into the traction power supply system(TPSS). However, traditional research on the TPSS operation strategy has not fully considered the risk of unce...; 关键词：Rail transit green energy system improved light robust(ILR)optimization two-step load check time resolution operation strategy

Self-defined dual charge percolation networks for solution-processed multithreshold transistors Check for updates: 《npj Flexible Electronics》2024年第1期1-10,共10页Jung Woo Moon Seunghan Kim Jin Hyeon Kim Sunil V.Barma Sang Young Jeong Jinho Keum Ho Sun Lim Youngjae Yoo Han Young Woo Sae Byeok Jo Moon Sung Kang Jeong Ho Cho; supported by the National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(RS-2023-00234581 and RS-2024-00460364).; This study demonstrates multithreshold engineering of a solution-processed heterojunction electrochemical transistor using a blend of n-type CdSe tetrapod-shaped nanocrystals(TpNCs)and an n-type polymeric organic semi...; 关键词：HETEROJUNCTION TRANSISTORS CHARGE

Targeting SRSF10 might inhibit M2 macrophage polarization and potentiate anti-PD-1 therapy in hepatocellular carcinoma: 《Cancer Communications》2024年第11期1231-1260,共30页Jialiang Cai Lina Song Feng Zhang Suiyi WuGuiqi Zhu Peiling Zhang Shiping Chen Junxian Du Biao Wang Yufan Cai Yi Yang Jinglei Wan Jian Zhou Jia Fan Zhi Dai; supported by the National Natural Science Foundation of China(No.82372946 and No.82072670);the 12 Leading Project of the Science and Technology Committee of Shanghai Municipality(No.21Y21900100);the Project of Shanghai Municipal Health Commission(No.202140269).; Background:The efficacy of immune checkpoint blockade therapy in patients with hepatocellular carcinoma(HCC)remains poor.Although serine-and arginine-rich splicing factor(SRSF)family members play crucial roles in tumo...; 关键词：GLYCOLYSIS Histone lactylation Immune checkpoint blockade Serine and arginine rich splicing factor 10 Tumor-Associated Macrophage

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