This study was financially supported by National Natural Science Foundation of China(Grant no.21877111 and no.21922812);China Postdoctoral Science Foundation(199936).
Current yeast metabolic engineering in isoprenoids production mainly focuses on rewiring of cytosolic metabolic pathway.However,the precursors,cofactors and the enzymes are distributed in various sub-cellular compartm...
This work was funded by Bundesministerium für Bildung und Forschung(BMBF)(FKZ 031A568B),in the frame of the ERA-NET-IB project“NeBrasCa”.
The isoprenoid brasilicardin A is a promising immunosuppressant compound with a unique mode of action,high potency and reduced toxicity compared to today's standard drugs.However,production of brasilicardin has been h...
This research was financially supported by the Novo Nordisk Foundation(grant number NNF15OC0016592);BAD was supported by the ERASMUS Traineeship program.We acknowledge Mette Kristensen for technical assistance on HPLC analysis.
Astaxanthin is a red-colored carotenoid,used as food and feed additive.Astaxanthin is mainly produced by chemical synthesis,however,the process is expensive and synthetic astaxanthin is not approved for human consumpt...
the National Natural Science Foundation of China(Grant NO.21276289);the Natural Science Foundation of Guangdong Province(NO.2015A030311036);the Project of the Scientific and Technical Program of Guangdong Province(NO.2015A010107004);the Project of the Scientific and Technical Program of Guangzhou(NO.201607010028)for their financial support.
Isoprenoids are the most abundant and highly diverse group of natural products.Many isoprenoids have been used for pharmaceuticals,nutraceuticals,flavors,cosmetics,food additives and biofuels.Carotenoids and isoprenoi...