ANTITUMOR

作品数：470被引量：1206H指数：15
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相关机构：北京大学天津医科大学中国药科大学福建省亚热带植物研究所更多>>
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Dietary long-chain fatty acid metabolism boosts antitumorimmune response
《Cancer Communications》2024年第5期580-583,共4页Jiaming Wang Xuetao Cao 
National Natural Science Foundation of China,Grant/Award Number:82388201;Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences,Grant/Award Number:2021-1-I2M-017。
Overcoming resistance to immune checkpoint blockade(ICB)therapy will pave the way for effective ICB cancer immunotherapy since a large proportion of cancer patients are not responsive to ICB immunotherapy[1].The molec...
关键词：METABOLISM cancer IMMUNE 
Current applications of tumor local ablation(TLA)combined with immune checkpoint inhibitors in breast cancer treatment
《Cancer Drug Resistance》2024年第1期439-458,共20页Lingpeng Tang Dandan Wang Ting Hu Xiaoying Lin Songsong Wu 
supported by the Fujian Science and Technology Innovation Joint Funding Program(No.2023Y9332).
Breast cancer is one of the most common cancers in women globally,posing significant challenges to treatment because of the diverse and complex pathological and molecular subtypes.The emergence of immune checkpoint in...
关键词：Tumor microenvironment antitumor immune response ablation immune checkpoint inhibitors 
Immunostimulant nanomodulator boosts antitumor immune response in triple negative breast cancer by synergism of vessel normalization and photothermal therapy被引量：1
《Nano Research》2023年第8期11149-11163,共15页Hao Jiang Yilang He Jia Zhao Ruimin Chang Hailun He Tan Li Xingyu Zhang Bo Shu Wenxuan Zhang Huaiyu Wang Jing Liu Shubing Zhang Yuetao Zhao 
supported by grants from the National Natural Science Foundation of China(Nos.32000931,81672632,81972312,and 82103184);the Natural Science Foundation of Hunan Province for outstanding Young Scholars(No.2021JJ20083);Natural Science Foundation of Hunan Province of China(Nos.2021JJ30912,2021JJ40720 and 2021JJ30950);the science and technology innovation Program of Hunan Province(No.2022RC1165);the Open Sharing Fund for the Largescale Instruments and Equipment of Central South University,Changsha,China.
Tumor vascular dysfunction and immune suppression predict poor outcomes of tumor therapy.Combination of photothermal therapy(PTT)and vessel normalization with tumor immunotherapy is promising to augment antitumor bene...
关键词：vessel normalization photothermal therapy black phosphorus triple negative breast cancer transforming growth factor-β 
Nanovaccines for cancer immunotherapy:Current knowledge and future perspectives被引量：3
《Chinese Chemical Letters》2023年第8期57-68,共12页Yiming Wu Zhe Zhang Yuquan Wei Zhiyong Qian Xiawei Wei 
supported by the National Science Foundation for Excellent Young Scholars(No.32122052);National Natural Science Foundation Regional Innovation and Development(No.U19A2003).
Cancer immunotherapy harnesses the immune system to attack tumors and has received extensive attention in recent years.Cancer vaccines as an important branch of immunotherapy are designed for delivering tumor antigens...
关键词：Cancer immunotherapy Cancer vaccines NANOPARTICLES Antitumor immune response Clinical transformation 
Distinct T helper cell-mediated antitumor immunity:T helper 2 cells in focus
《Cancer Pathogenesis and Therapy》2023年第1期76-86,共11页Rafael Cardoso Maciel Costa Silva Marcela Freitas Lopes Leonardo Holanda Travassos 
This work was supported by Coordination for the Improvement of Higher Education Personnel(CAPES),Carlos Chagas Filho Foundation for Supporting Research in the State of Rio de Janeiro(grant number FAPERJ E−26/200.628/2022);National Counsel of Technological and Scientific Development(CNPq)Brazil.
The adaptive arm of the immune system is crucial for appropriate antitumor immune responses.It is generally accepted that clusters of differentiation 4^(+)(CD4^(+))T cells,which mediate T helper(Th)1 immunity(type 1 i...
关键词：Cancer IMMUNOLOGY Adaptive immunity IMMUNOTHERAPY IMMUNOGENETICS Antitumor immune response 
Serum Spondin-2 expression,tumor invasion,and antitumor immune response in patients with cervical cancer被引量：1
《World Journal of Clinical Cases》2022年第36期13304-13312,共9页Ling-Li Zhang Song Lin Yan Zhang Dong-Mei Yao Xin Du 
BACKGROUND Cervical cancer is a gynecological malignancy common in middle-aged and older patients,with a high mortality rate.Spondin-2 is an extracellular matrix protein that involved in innate and acquired immune res...
关键词：Cervical cancer Spondin-2 Invasion and infiltration Immune response Prognosis Malignant tumor 
Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect被引量：2
《Bioactive Materials》2022年第6期97-106,共10页Haoran Wang Honghui Liu Yunfei Guo Wenjing Zai Xianghui Li Wei Xiong Xiaozhi Zhao Yingfang Yao Yiqiao Hu Zhigang Zou Jinhui Wu 
supported by National Key R&D Program of China(2017YFA0205400);National Natural Science Foundation of China(No.31872755,81872811,32171372);Jiangsu Outstanding Youth Funding(BK20190007);supported by the Central Fundamental Research Funds for the Central Universities(02141438473).
The ideal photodynamic therapy(PDT)should effectively remove the primary tumor,and produce a stronger immune memory effect to inhibit the tumor recurrence and tumor metastasis.However,limited by the hypoxic and immuno...
关键词：CHLORELLA Photodynamic therapy Controlled adjuvants release Systemic antitumor immune response Immune memory effect 
Correction to:Enhancing the HSV-1-mediated antitumor immune response by suppressing Bach1
《Cellular & Molecular Immunology》2022年第6期754-754,共1页Chaohu Pan Qiaomei Cai Xiaorong Li Lili Li Liping Yang Yu Chen Junxiao Liu Wancheng Liu Meiling Gao Tianqi Sui Xiaoyang Wang Huiming Fan Jiayin Ruan Yueyue Shi Saihua Chen Lucy SCheng Jiayong Liu Heng Yang Genhong Cheng 
In the version of this article initially published,a grant name and the acknowledgment information were missing.The grant name and acknowledgment information have been added at the end of Acknowledgments:J.L.is suppor...
关键词：Medical initially THANK 
Enhancing the HSV-1-mediated antitumor immune response by suppressing Bach1被引量：1
《Cellular & Molecular Immunology》2022年第4期516-526,共11页Chaohu Pan Qiaomei Cai Xiaorong Li Lili Li Liping Yang Yu Chen Junxiao Liu Wancheng Liu Meiling Gao Tianqi Sui Xiaoyang Wang Huiming Fan Jiayin Ruan Yueyue Shi Saihua Chen Lucy S.Cheng Jiayong Liu Heng Yang Genhong Cheng 
This project was financially supported by the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2021-I2M-1-047 and 2019-I2M-5-049);National Science Funds of China(82073181,81802870 and 82102371);Nonprofit Central Research Institute Fund of Chinese Academy of Medical Sciences(2020-PT310-006,2019XK310002 and 2018TX31001);as well as NIH R01AI069120,AI158154,and AI140718 grants,the UCLA AIDS Institute;UCLA David Geffen School of Medicine-Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research Award Program;H.Y.is supported by science funds from Jiangsu Province(BK20211554,BK20170407);the Innovative and Entrepreneurial Team grant(2018-2021)from Jiangsu Province;L.L.is supported by Innovative and Entrepreneurial Doctor grant(2020-2022)from Jiangsu Province.
Background In 2015,herpes simplex virus 1(HSV-1)-derived talimogene laherparepvec(T-VEC)was the first oncolytic virus approved by the US Food and Drug Administration as a therapeutic agent for cancer treatment.However...
关键词：IFN stimulated genes Bach1 HSV-1 HEMIN Antitumor immunity 
CXCL13 expression in mouse 4T1 breast cancer microenvironment elicits antitumor immune response by regulating immune cell infiltration被引量：2
《Precision Clinical Medicine》2021年第3期155-167,共13页Qizhi Ma Yue Chen Qing Qin Fuchun Guo Yong-sheng Wang Dan Li 
Thisworkwas supported by theNationalNatural Science Foundation of China(grant No.81402354).
Breast cancer is the most commonly diagnosed cancer type and the leading cause of cancer-related deaths among women worldwide.Previous studies have reported contradictory performance of chemokine CXC motif ligand 13(C...
关键词：CXCL13 triple negative breast cancer 4T1 tumor microenvironment CXCR5 
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