NEUREGULIN-1

作品数:53被引量:124H指数:6
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相关领域:医药卫生更多>>
相关作者:冯灵美宋耀明刘超赵炜疆蔡季平更多>>
相关机构:复旦大学广西医科大学第二军医大学复旦大学上海医学院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金广西研究生教育创新计划更多>>
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  • 期刊=Chinese Medical Journalx
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Neuregulin-1 attenuates mitochondrial dysfunction in a rat model of heart failure被引量:16
《Chinese Medical Journal》2012年第5期807-814,共8页GUO Yong-fang ZHANG Xiao-xia LIU Yong DUAN Hong-yan JIE Bing-zhang WU Xue-si 
Background Mitochondrial dysfunction plays a pivotal role in the progression of left ventricular (LV) remodeling and heart failure (HF). Recombinant human neuregulin-1 (rhNRG-1) improves cardiac function in mode...
关键词:NEUREGULIN-1 heart failure MITOCHONDRIA CARDIOPROTECTION 
Neuregulin-1 preconditioning protects the heart against ischemia/reperfusion injury through a PI3K/Akt-dependent mechanism被引量:17
《Chinese Medical Journal》2010年第24期3597-3604,共8页FANG Shan-juan WU Xue-si HAN Zhi-hong ZHANG Xiao-xia WANG Chun-mei LI Xin-yan LU Ling-qiao ZHANG Jing-lan 
This study was supported by the Natural Science Foundation of Beijing, China (No. 7102043) and by a Grant-in-Aid for Scientific Research from Beijing Municipal Health Bureau and the Beijing Journal of Traditional Chinese Medicine (No. QN2009-008).
Background Neuregulin-1 (NRG-1), the ligand of the myocardial ErbB receptor, is a protein mediator with regulatory actions in the heart. This study investigated whether NRG-1 preconditioning has protective effects o...
关键词:ischemia-reperfusion injury MYOCARDIUM NEUREGULIN-1 1-phosphatidylinositol 3-kinase 
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