Background Mitochondrial dysfunction plays a pivotal role in the progression of left ventricular (LV) remodeling and heart failure (HF). Recombinant human neuregulin-1 (rhNRG-1) improves cardiac function in mode...
This study was supported by the Natural Science Foundation of Beijing, China (No. 7102043) and by a Grant-in-Aid for Scientific Research from Beijing Municipal Health Bureau and the Beijing Journal of Traditional Chinese Medicine (No. QN2009-008).
Background Neuregulin-1 (NRG-1), the ligand of the myocardial ErbB receptor, is a protein mediator with regulatory actions in the heart. This study investigated whether NRG-1 preconditioning has protective effects o...