supported by grants from the Innovation and Cultivation Fund Project of the Seventh Medical Center,PLA General Hospital(No.QZX-2023-7);Postdoctoral Science Foundation of China(No.2021M691649);Postdoctoral Science Foundation of Jiangsu Province(No.2021K524C).
Objective:Nucleotide excision repair(NER)plays a vital role in maintaining genome stability,and the effect of NER gene polymorphisms on hepatoblastoma susceptibility is still under investigation.This study aimed to ev...
supported in part by National Natural Science Foundation of China(No.81101889)
Objective: To investigate the association between gastric cardia adenocarcinoma (GCA) and ten functional single nueleotide polymorphisms (SNPs), including TPY3BPI rs560191 G〉C, CASP8 rs1035142 G〉T, CASP7 rs3127...
Objectives: To investigate the correlation between glutathione S-transferase P1 (GSTP1) Ilel05Val polymorphism and colorectal cancer (CRC) risk. Methods: Studies were identified to investigate the association be...
Objective: To estimate the relationship between genetic polymorphisms of X-ray repair cross- complementing group 1 (XRCC1) and the susceptibility to childhood acute lymphoblastic leukemia (ALL). Methods: Relevan...
Objective:To assess the association between X-ray repair cross-complementating group 1 (XRCC1) polymorphisms and pancreatic cancer.Methods:We searched MEDLINE,Web of Science and HuGE Navigator at June 2010,and the...
supported by the grants from the National Eleveth-Five-Year Key Task Project of China(No.2006BA102A01);the National "863" High Tech R & D Program of China(No.2006AA02A401);China-Sweden International Scientific and Technological Cooperative Project (No.09ZCZDSF04100)
Objective: A number of studies have reported the association of "XPA", "XPC", "XPD/ERCC2" gene polymorphisms with lung cancer risk. However, the results were conflict. To clarify the impact of polymorphisms of ...
supported in part by Key Grant of the National Natural Science Foundation of China (No. 30730080);National Natural Science Foundation of China (No. 30972541, 30901233);National Outstanding Youth Science Foundation of China (No. 30425001);Key Laboratory of Laboratory Mecicine of Jiangsu Province (No. XK200731)
Objective:Vitamin D and its receptor(VDR) involve in multiple cellular processes and play an important role in the initiation and progression of malignancy.Thus we hypothesized that plasma vitamin D levels and sing...
supported by the grant from Department of Education of Liaoning Province, China (No. 2008S232)
Objective: Hepatocellular carcinoma (HCC) is a complex disease which associates with both environmental and genetic factors. The purpose of this study was to investigate whether the genetic polymorphisms of UDP-glu...
supported by a grant from Scholarship Council Fund of Shanxi Province (No.200565)
Objective: To explore the relationships of the polymorphisms of xeroderma pigmentosum C (XPC) and the susceptibility of esophageal cancer (EC) in Changzhi area, China. Methods: The study was conducted by a case...
supported by the National Natural Science Foundation of China (No.39860032);the Youth Science Foundation of Guangxi (No.0833097)
Objective: Aflatoxin B1 (AFB1), which can cause the formation of AFB1-DNA adducts, is a known human carcinogen. AFB1-exposure individuals with inherited susceptible carcinogen-metabolizing or repairing genotypes ma...