HEPATOBLASTOMA

作品数：47被引量：183H指数：8
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相关领域：医药卫生更多>>
相关作者：王平张柏和吴孟超张红卫石梅更多>>
相关机构：山东大学河南省人民医院首都医科大学更多>>
相关期刊：《Surgical Science》《Chinese Medical Journal》《Signal Transduction and Targeted Therapy》《Precision Clinical Medicine》更多>>
相关基金：国家自然科学基金天津市自然科学基金更多>>
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Nucleotide excision repair gene polymorphisms and hepatoblastoma susceptibility in Eastern Chinese children:A five-center case-control study
《Chinese Journal of Cancer Research》2024年第3期298-305,共8页Huimin Yin Xianqiang Wang Shouhua Zhang Shaohua He Wenli Zhang Hongting Lu Yizhen Wang Jing He Chunlei Zhou 
supported by grants from the Innovation and Cultivation Fund Project of the Seventh Medical Center,PLA General Hospital(No.QZX-2023-7);Postdoctoral Science Foundation of China(No.2021M691649);Postdoctoral Science Foundation of Jiangsu Province(No.2021K524C).
Objective:Nucleotide excision repair(NER)plays a vital role in maintaining genome stability,and the effect of NER gene polymorphisms on hepatoblastoma susceptibility is still under investigation.This study aimed to ev...
关键词：Nucleotide excision repair POLYMORPHISMS HEPATOBLASTOMA SUSCEPTIBILITY 
A multicenter prospective study on the management of hepatoblastoma in children:a report from the Chinese Children's Cancer Group
《World Journal of Pediatrics》2024年第6期590-601,共12页Meng-Jie Tang Xiao-Li Ma Xiang-Ling He Wei-Hua Pan Xiao-Hong Zhang Sha-Yi Jiang Ju Gao Fu Li Wei Yao Song Gu Wei-Ling Zhang Qiang Zhao Shi-Hao Huang Yong-Jun Fang Wei Liu Hui-Zhong Niu Chun-Mei Wang Li-Rong Sun Hui Gao Yun-Peng Dai Shun-Gen Huang Zhi-Yong Zhong Xi-Ge Wang Zhong-Rong Li Liang-Chun Yang Ye-Ming Wu Huan-Min Wang Xin Sun Xiao-Jun Yuan 
supported by the Shanghai Municipal Hospital New Frontier Technology Joint Key Project,Shanghai,China(No.SHDC12019115).
Background This study aimed to identify survival risk factors in Chinese children with hepatoblastoma(HB)and assess the effectiveness of the new treatment protocol proposed by the Chinese Children's Cancer Group(CCCG)...
关键词：ALPHA-FETOPROTEIN HEPATOBLASTOMA MULTICENTER Prospective study SURVIVAL 
Blastomas of the digestive system in adults:A review
《World Journal of Gastrointestinal Surgery》2024年第4期1030-1042,共13页Yu Liu Tony El Jabbour Jonathan Somma Yukihiro Nakanishi Saverio Ligato Hwajeong Lee Zhi-Yan Fu 
Blastomas,characterized by a mixture of mesenchymal,epithelial,and undifferentiated blastematous components,are rare malignant neoplasms originating from precursor blast cells.This review focuses on digestive system b...
关键词：Adult blastomas Gastroblastoma HEPATOBLASTOMA PANCREATOBLASTOMA Digestive system 
Pediatric Hepatoblastoma: A Case Report and Review of the Literature
《Open Journal of Pediatrics》2024年第2期266-271,共6页Hanae Bahari Hanane Hajaj Hind Zahiri Ayyad Ghanam Abdeladim Babakhouya Maria Rkain 
Introduction and Objective: Hepatoblastoma is the most frequent malignant embryonal liver tumor, and its incidence is increasing. Children under 3 years of age are particularly affected. The etiology is largely unknow...
关键词：HEPATOBLASTOMA LIVER CHILDREN ALPHA-FETOPROTEIN 
Computer-assisted three-dimensional individualized extreme liver resection for hepatoblastoma in proximity to the major liver vasculature
《World Journal of Gastrointestinal Surgery》2024年第4期1066-1077,共12页Wen-Li Xiu Jie Liu Jing-Li Zhang Jing-Miao Wang Xue-Feng Wang Fei-Fei Wang Jie Mi Xi-Wei Hao NanXia Qian Dong 
Supported by National Natural Science Foundation of China,No.82293665;Anhui Provincial Department of Education University Research Project,No.2023AH051763.
BACKGROUND The management of hepatoblastoma(HB)becomes challenging when the tumor remains in close proximity to the major liver vasculature(PMV)even after a full course of neoadjuvant chemotherapy(NAC).In such cases,e...
关键词：Children HEPATOBLASTOMA Surgery THREE-DIMENSIONAL COMPUTER-ASSISTED 
Hepatoblastoma with neonatal necrotizing enterocolitis:Two case reports
《Cancer Innovation》2023年第6期532-536,共5页Sidou He Xisi Wang Chao Duan Wen Zhao Chiyi Jiang Shihan Zhang Binglin Jian Wei Yang Tong Yu Libing Fu Huanmin Wang Xiaoli Ma 
Beijing Municipal Natural Science Foundation,Grant/Award Number:7222054;Beijing Research Ward Project,Grant/Award Number:BCRW202101。
We report two children with hepatoblastoma(HB)with a history of neonatal necrotizing enterocolitis(NEC).Case 1 was diagnosed with HB at 5 months of age.Liver enlargement was found during the NEC operation at 3 months ...
关键词：HEPATOBLASTOMA LGR5 low birth weight neonatal necrotizing enterocolitis premature delivery 
miR-181b-5p/SOCS2/JAK2/STAT5 axis facilitates the metastasis of hepatoblastoma
《Precision Clinical Medicine》2023年第4期189-199,共11页Yong Lv Xiaolong Xie Guoyou Zou Meng Kong Jiayin Yang Jing Chen Bo Xiang 
supported by Scientific Research Starting Foundation for Introduced Talents(to Jing Chen);Sichuan Science and Technology Department(Grants No.2022NSFSC1301&2020YFS0108);1·3·5 project for disciplines of excellence,West China Hospital,Sichuan University(Grants No.ZYJC18003,2021HXFH020);Shandong Provincial Natural Science Foundation(Grant No.ZR2022MH229).
Introduction:Hepatoblastoma(HB)is a malignant liver tumor predominantly found in children and tumor metastasis is one of the main causes of poor prognosis in affected patients.The precise molecular mechanisms responsi...
关键词：miR-181b SOCS2 METASTASIS HEPATOBLASTOMA CHILDREN 
Elevated extracellular calcium ions accelerate the proliferation and migration of HepG2 cells and decrease cisplatin sensitivity
《The Journal of Biomedical Research》2023年第5期340-354,共15页Haozhe Xu Yiming Zhou Jing Guo Tao Ling Yujie Xu Ting Zhao Chuanxin Shi Zhongping Su Qiang You 
funded by the Jiangsu Medical Scientific Research Project of Jiangsu Health Commission(to Q.Y.);the 789 Outstanding Talent Program of SAHNMU(Grant No.789ZYRC 202070102 to Q.Y.);the Guangzhou Key Medical Discipline Construction Project(to Q.Y.);the National Natural Science Foundation of China(Grant Nos.81870409 and 81671543 to Q.Y.).
Hepatoblastoma is the most frequent liver malignancy in children.HepG2 has been discovered as a hepatoblastoma-derived cell line and tends to form clumps in culture.Intriguingly,we observed that the addition of calciu...
关键词：HepG2 HEPATOBLASTOMA calcium ion FAK CaMKⅡ cisplatin resistance 
Application of endoscopic retrograde cholangiopancreatography for treatment of obstructive jaundice after hepatoblastoma surgery:A case report
《World Journal of Clinical Cases》2023年第11期2502-2509,共8页Jun Shu Hu Yang Jun Yang Hong-Qiang Bian Xin Wang 
BACKGROUND We aimed to investigate the effectiveness of endoscopic retrograde cholangiopan-creatography(ERCP)for treating obstructive jaundice(OJ)post hepatoblastoma(HB)surgery(post-HB OJ)by analyzing the data of a ca...
关键词：Endoscopic retrograde cholangiopancreatography HEPATOBLASTOMA Pediatric patients Obstructive jaundice Case report 
Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis被引量：4
《Protein & Cell》2022年第9期683-688,共6页Li Yang Jin Chen Jianqing Liang Yufeng Zhang Qingzhe Wang Xiaojun Ren Jinsong Wei Qianchun Gong Jiting Zhang Ning Jiang Xinhua Lin Jin Li Bing Zhao 
Dear Editor,Hepatoblastoma(HB)is a predominant hepatic neoplasm that develops in children from 0 to 4 years of age at the rate of 2.16 per 1,000,000.It originates from abnormal differentiation of hepatocyte precursors...
关键词：FETAL diagnosis chemotherapy 
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