ALPHA-FETOPROTEIN

作品数：160被引量：821H指数：17
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Prognostic value of combined detection of alpha-fetoprotein,plasma prothrombin activity,and serum prealbumin in acute-on-chronic liver failure
《World Journal of Gastrointestinal Surgery》2025年第2期97-104,共8页Rui-Xian Duan Ling Liu Yan Wang Wen-Ming Wu 
BACKGROUND Acute-on-chronic liver failure(ACLF)is a liver disease based on chronic liver disease,which is significantly influenced by clinical treatment regimen and disease status,and despite the existence of multiple...
关键词：ALPHA-FETOPROTEIN Prothrombin activity PREALBUMIN Acute-on-chronic liver failure Prognostic value 
CRAFITY score and nomogram predict the clinical efficacy of lenvatinib combined with immune checkpoint inhibitors in hepatocellular carcinoma
《World Journal of Gastroenterology》2025年第7期51-62,共12页Xue Yin Na Deng Xiao-Yan Ding Jing-Long Chen Wei Sun 
Supported by the Capital’s Funds for Health Improvement and Research,No.SF202222175.
BACKGROUND The CRAFITY score is mainly utilized for hepatocellular carcinoma(HCC)patients receiving atezolizumab and bevacizumab,with little investigation in its predictive capacity for alternative regimens,such as le...
关键词：Hepatocellular carcinoma Lenvatinib Immune checkpoint inhibitors C-reactive protein ALPHA-FETOPROTEIN 
The impact of alpha-fetoprotein(AFP),child-turcotte-pugh(CTP)score and disease staging on the survival of hepatocellular carcinoma(HCC)patients:a retrospective cohort from single oncology center
《Oncology Research》2025年第1期149-160,共12页NASSER MULLA YOUSEF KATIB ASIM M.ALMUGHAMSI DUAA S.ALKHAYAT MOHAMED MOSAAD SAMIR T.ALFOTIH RAWAN ALAOFI 
Background:Hepatocellular carcinoma(HCC)is the most common cause of cancer-related death in Saudi Arabia.Our study aimed to investigate the patterns of HCC and the effect of TNM staging,Alfa-fetoprotein(AFP),and Child...
关键词：Hepatocellular carcinoma Pattern Alpha-fetoprotein(AFP) Child-turcotte-pugh Progression free survival 
Clinical Significance of Alpha-Fetoprotein Levels in Artificial Liver Therapy for Liver Failure
《Journal of Clinical and Nursing Research》2025年第1期305-313,共9页Xiju Guo Weibo Guo Luyao Wang Yongping Wang Mingmei Liao Yingshan Liao 
Objective: Through the treatment of liver failure using artificial liver plasma exchange (PE), this study aims to explore the predictive value and clinical significance of alpha-fetoprotein (AFP) levels in the prognos...
关键词：ALPHA-FETOPROTEIN Artificial liver support system Plasma exchange Liver failure prognosis Hepatocyte regeneration 
Diagnostic Value of Abnormal Prothrombin for Primary Liver Cancer
《Proceedings of Anticancer Research》2024年第6期113-119,共7页Hanyu Qiu 
Objective: To investigate the diagnostic value of abnormal serum prothrombin levels in hepatocellular carcinoma (HCC). Methods: A total of 298 patients were diagnosed with HCC at Hunan Provincial People’s Hospital be...
关键词：Abnormal prothrombin ALPHA-FETOPROTEIN Primary liver cancer Hepatitis B virus CIRRHOSIS 
Exploring Circulating Tumor Cells: Detection Methods and Biomarkers for Clinical Evaluation in Hepatocellular Carcinoma
《Journal of Clinical and Translational Hepatology》2024年第12期1020-1042,共23页Chin-Mu Hsu Yi-Chang Liu Jee-Fu Huang 
supported in part by grants from the Ministry of Science and Technology,Taiwan(MOST 107-2314-B-037-082-MY3 to JFH,110-2314-B-03-073-MY3 to JFH);the National Science and Technology Council,Taiwan(NSTC112-2314-B-037-072 to YCL);the National Yang Ming Chiao Tung University-Kaohsiung Medical University Joint Research Project(NYCU-KMU-111-I001 to JFH,NYCU-KMU-112-I001 to JFH);and Kaohsiung Medical University Hospital(KMUH110-0R05 to JFH,KMUH110-0R20 to YCL,KMUH111-1M16 to YCL,KMUH111-1M17 to CMH,KMUH111-1R06 to JFH,KMUH SH11208 to YCL,KMUH-DK(B)110001-3 to YCL,KMUH-DK109006-2 to YCL).
Circulating tumor cells(CTCs),originating from primary neoplastic tissues,infiltrate blood vessels,migrate through the bloodstream,and establish secondary tumor foci.The detection of CTCs holds significant promise for...
关键词：Circulating tumor cells CTC Hepatocellular carcinoma HCC Clinical application CTC enrichment BIOMARKER PROGRESSION Microvascular invasion MVI ALPHA-FETOPROTEIN AFP. 
Liver cell cancer surveillance practice in Nigeria:Pitfalls and future prospects
《World Journal of Hepatology》2024年第10期1132-1141,共10页Yusuf Musa Ijeoma M Ifeorah Abubakar Sadiq Maiyaki Rahama Mohammad Almustapha Yussuf Abdulkadir Maisuna Habib Tijjani Saleh Abdulmumini Yakubu 
Hepatocellular carcinoma(HCC)is a disease of public health concern in Nigeria,with chronic hepatitis B and C infections contributing most to the disease burden.Despite the increasing incidence of HCC,surveillance prac...
关键词：Hepatocellular cancer Surveillance ALPHA-FETOPROTEIN ULTRASONOGRAPHY Des-gamma-carboxy prothrombin Early disease Intermediate disease Late disease Advance disease 
Inflammation-related markers and prognosis of alpha-fetoprotein producing gastric cancer
《World Journal of Gastrointestinal Oncology》2024年第9期3875-3886,共12页Lu Zhang Yan-Ping Chen Min Ji Le-Qian Ying Chun-Chun Huang Jing-Yi Zhou Lin Liu 
BACKGROUND Inflammation-related markers including neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),monocyte-to-lymphocyte ratio(MLR),systemic immune-inflammation index(SII),systemic inflammation r...
关键词：Alpha-fetoprotein producing gastric cancer Inflammatory indicator PROGNOSIS Dynamic changes Tumor immune microenvironment 
Tumor burden score and alpha-fetoprotein level predict prognosis of patients with unresectable hepatocellular carcinoma treated with tyrosine kinase inhibitor and anti-PD-1 antibody
《iLIVER》2024年第3期22-31,共10页Shichuan Tang Tingfeng Huang Cong Luo Jun Fu Kailing Zhang Qingjing Chen Jie Kong Jianxi Zhang Zhenghong Sun Yongkang Diao Kongying Lin Yongyi Zeng 
supported by the National Natural Science Foundation of China(No.62275050);the Major Research Projects for Young and Middle-aged Talent of Fujian Provincial Health Commission(No.2021ZQNZD013);Fujian Provincial Clinical Research Center for Hepatobiliary and Pancreatic Tumors(Grant number:2020Y2013);the Scientific Foundation of Fuzhou Municipal Health Commission(Grant number:2021-S-wp1).
Background:Tyrosine kinase inhibitors(TKIs)and anti-PD-1 antibodies in combination provide survival benefits for patients with unresectable hepatocellular carcinoma(uHCC).However,the tool used to determine which patie...
关键词：Hepatocellular carcinoma Tyrosine kinase inhibitor Anti-PD-1 antibody Tumor burden score ALPHA-FETOPROTEIN 
A multicenter prospective study on the management of hepatoblastoma in children:a report from the Chinese Children's Cancer Group
《World Journal of Pediatrics》2024年第6期590-601,共12页Meng-Jie Tang Xiao-Li Ma Xiang-Ling He Wei-Hua Pan Xiao-Hong Zhang Sha-Yi Jiang Ju Gao Fu Li Wei Yao Song Gu Wei-Ling Zhang Qiang Zhao Shi-Hao Huang Yong-Jun Fang Wei Liu Hui-Zhong Niu Chun-Mei Wang Li-Rong Sun Hui Gao Yun-Peng Dai Shun-Gen Huang Zhi-Yong Zhong Xi-Ge Wang Zhong-Rong Li Liang-Chun Yang Ye-Ming Wu Huan-Min Wang Xin Sun Xiao-Jun Yuan 
supported by the Shanghai Municipal Hospital New Frontier Technology Joint Key Project,Shanghai,China(No.SHDC12019115).
Background This study aimed to identify survival risk factors in Chinese children with hepatoblastoma(HB)and assess the effectiveness of the new treatment protocol proposed by the Chinese Children's Cancer Group(CCCG)...
关键词：ALPHA-FETOPROTEIN HEPATOBLASTOMA MULTICENTER Prospective study SURVIVAL 
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