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PROGRESSION: 作品数：1059被引量：3446H指数：25; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王占祥张良牛军李伟王传新更多>>; 相关机构：中国科学院同济大学附属同济医院东南大学复旦大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>

A novel Wnt/β-catenin signaling gene signature for progression and metastasis of gastric cancer: 《Oncology Research》2025年第5期1199-1215,共17页JIA CHEN FEI JIANG KAIYI NIU HAODONG ZHAO LI LI HONGZHU YU; funded by the Natural Science Research Project of Anhui Educational Committee(2023AH050650);the Research Fund Program of Anhui Medical University(2023xkj176).; Backgrounds:As cancer progresses through various stages of malignancy,metastasis,and drug resistance,the Wnt/-catenin signaling is frequently dysregulated.Despite advancements in medical technology and therapeutic str...; 关键词：Gastric Cancer(GC) Signature genes Prognosis Carboxypeptidase Z(CPZ) Adipocyte Enhancer Binding Protein 1(AEBP1)

Impact of diabetes duration and hyperglycemia on the progression of diabetic kidney disease:Insights from the KNHANES 2019-2021: 《World Journal of Diabetes》2025年第5期124-134,共11页Chang Seong Kim Sang Heon Suh Hong Sang Choi Eun Hui Bae Seong Kwon Ma Bongseong Kim Kyung-Do Han Soo Wan Kim; Supported by the National Research Foundation(NRF)of Korea,No.RS-2023-00217317。; BACKGROUND Diabetes is a significant risk factor for chronic kidney disease,and diabetic kidney disease(DKD)is prevalent among patients with diabetes.Previous studies have indicated that the duration of diabetes and p...; 关键词：Diabetic nephropathy Diabetic mellitus Glycemic control Chronic kidney disease ALBUMINURIA

Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein: 《World Journal of Gastrointestinal Oncology》2025年第4期427-441,共15页Zi-Wei Xiao Ying-Chao Zeng Lin-Tao Ji Jia-Tao Yuan Lin Li; Supported by the National Natural Science Foundation of China,No.81000201.; BACKGROUND Esophageal cancer(ESCA)is among the most prevalent and lethal tumors globally.While nitric oxide synthase 1(NOS1)is recognized for its important in-volvement in various cancers,its specific function in ESCA...; 关键词：Nitric oxide synthase 1 Nitric oxide synthase 1 adaptor protein AUTOPHAGY Phosphatidylinositol 3-kinase/protein kinase B pathway Esophageal cancer

NOP56 promotes hepatocellular carcinoma progression through 2'-O-methylation: 《Genes & Diseases》2025年第2期33-36,共4页Shuxin Yang Juan Liu Shengxin Luo Wentao Wang Jingxiang Xu; funded by the High-level Talent Research Funds of Gannan Medical University (No.QD202122).; Hepatocellular carcinoma(HCC)is a common malignant tumor and one of the leading causes of cancer-related deaths,with the fourth-highest incidence rate and the second-highest mortality rate in China.1 Currently,HCC is ...; 关键词：MORTALITY CHEMOTHERAPY surgery

The role of glutathione peroxidase 4 in the progression,drug resistance,and targeted therapy of non-small cell lung cancer: 《Oncology Research》2025年第4期863-872,共10页JIAHENG WEI LIANGMING ZHU; Lung cancer is one of the main causes of cancer-related deaths globally,with non-small cell lung cancer(NSCLC)being the most prevalent histological subtype of lung cancer.Glutathione peroxidase 4(GPX4)is a crucial ant...; 关键词：Non-small cell lung cancer(NSCLC) Glutathione peroxidase 4(GPX4) Drug resistance INHIBITOR Biological function

TMEM33,an oncogene regulated by miR-214-3p,promotes the progression of lung adenocarcinoma through the Wnt/β-catenin signaling pathway: 《Oncology Research》2025年第4期905-917,共13页GUANGXIAN YOU QIAO YANG XIN LI LILI CHEN; Background:Lung cancer remains a major factor causing cancer-associated mortality globally.While there have been advancements in treatment options,advanced lung cancer patients still have poor outcomes.This study aims...; 关键词：Lung adenocarcinoma(LUAD) Transmembrane protein 33(TMEM33) miR-214-3p Wingless(Wnt) Malignant progression

COPB2 promotes hepatocellular carcinoma progression through regulation of YAP1 nuclear translocation: 《Oncology Research》2025年第4期975-988,共14页BIAO WU XIANLIN GUO ZHISHI WU LIANG CHEN SUQING ZHANG; Objectives:Although Yes-associated protein 1(YAP1)is an important oncogene in hepatocellular carcinoma(HCC)progression,its nuclear localization prevents it from being considered a potential therapeutic target.Recently...; 关键词：Coatomer protein complex subunit beta 2(COPB2) Yes-associated protein 1(YAP1) Hepatocellular carcinoma(HCC)prognosis Cisplatin(DDP)

SNORD3B-2 promotes endometrial carcinoma progression by 2'-O-methylation modification of PLK1 and regulating RAB17 alternative splice: 《Genes & Diseases》2025年第2期90-93,共4页Xi Chen Yuping Du Bumin Xie Qianhui Li Yumeng Ji Yang Han Xiujie Sheng Shuo Chen Yang Zhao; supported by the National Natural Science Foundation of China (No.82072854 to Yang Zhao,82272985 to Shuo Chen);the Project for Key Medicine Discipline Construction of Guangzhou Municipality,Guangdong,China (No.2021-2023-17);the Science and Technology Projects in Guangzhou,Guangdong,China (No.202201020093 to Yang Zhao).; Endometrial cancer(EC)is one of the most common gynecological malignant tumors.Further investigation of the potential molecular mechanism of EC is important.Small nucleolar RNA(snoRNA)is a type of non-coding RNA,with ...; 关键词：PLK1 PI3K ENDOMETRIAL

Involvement of the ubiquitin-proteasome system in the regulation of the tumor microenvironment and progression: 《Genes & Diseases》2025年第2期227-243,共17页Yulan Huangg Yuan Gao Zhenghong Lin Hongming Miao; supported in part by the National Natural Science Foundation of China (No.82173134);the Chongqing Fund for Outstanding Youth (China) (No.CSTB2022NSCO-JOX0010).; The tumor microenvironment is a complex environment comprising tumor cells,non-tumor cells,and other critical non-cellular components.Some studies about tumor micro-environment have recently achieved remarkable progre...; 关键词：Adipose cells DEUBIQUITINATION IMMUNITY Tumor microenvironment Tumor-associated fibroblasts UBIQUITINATION

GATA6 in pancreatic cancer initiation and progression: 《Genes & Diseases》2025年第2期171-180,共10页Muyuan Ma Jianhong An Tingting Jiang Keping Xie; supported by the Guangzhou Ruiqian Biotech Company (No.20230330 to T.J.);National Natural Science Foundation of China (No.82072632);Guangzhou Municipality Bureau of Science and Technology (China) (No.202102010033 to K.X.);the Natural Science Foundation of Guangdong Province,China (No.2022A1515012585 to K.X.).; t Pancreatic ductal adenocarcinoma(PDA)is a lethal malignancy characterized by insidious onset and lack of effective therapy.The molecular pathogenesis of PDA remains to be understood fully.Transcriptional factor GATA...; 关键词：GATA6 INFLAMMATION Molecular diagnosis PANCREAS Targeted therapy TUMORIGENESIS

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