POLYMORPHISMS

作品数:634被引量:2320H指数:17
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相关领域:医药卫生更多>>
相关作者:王荣顾民韩志坚陶俊王子杰更多>>
相关机构:南京医科大学首都医科大学北京协和医院广西医科大学第一附属医院更多>>
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Selection and Analysis of Polymorphisms in Somaclonal Variants of Agave americana Resistant to Fusarium oxysporum via an Ethyl Methanesulphonate Treatment
《Phyton-International Journal of Experimental Botany》2021年第6期1727-1739,共13页Sheila Jazmín Reyes-Zambrano Carlos Alberto Lecona-Guzmán Federico Antonio Gutiérrez-Miceli Víctor Manuel Ruiz-Valdiviezo Arely Anayansi Vargas-Díaz 
Agave americana L.callus were exposed to different concentrations of ethyl methanesulphonate(EMS)0,15,30,45 and 60 mM and to different times of exposure(2 and 4 h).The viability and capacity of shoot formation were sh...
关键词:MUTAGENESIS POLYMORPHISMS genetic variation molecular markers 
Feed conversion ratio,residual feed intake and cholecystokinin type A receptor gene polymorphisms are associated with feed intake and average daily gain in a Chinese local chicken population被引量:9
《Journal of Animal Science and Biotechnology》2018年第4期794-802,共9页Zhenhua Yi Xing Li Wen Luo Zhenqiang Xu Congliang Ji Yan Zhang Qinghua Nie Dexiang Zhang Xiquan Zhang 
financial support from the High Technology Research and Development Program of China (2013AA102501);the National Key Technology Research and Development Program (2014BAD08B08);the China Agriculture Research System (CARS-41-G03,CARS-41-Z17)
Background: The feed conversion ratio(FCR) and residual feed intake(RFI) are common indexes in measuring feed efficiency for livestock. RFI is a feed intake adjusted for requirements for maintenance and production so ...
关键词:CCKAR CHICKEN FCR RFI SNP 
Polymorphisms in the FOXO gene are associated with growth traits in the Sanmen breeding population of the razor clam Sinonovacula constricta被引量:1
《Aquaculture and Fisheries》2018年第5期177-183,共7页Shumei Xie Donghong Niu Kanyun Wei Zhiguo Dong Jiale Li 
This work was supported by the National Natural Science Foundation of China[grant number 31472278];the National High Technology Research and Development Program of China(863 Program)[grant number 2012AA10A400-3];the Shanghai Universities Knowledge Service Platform[grant number ZF1206].
We identified the FOXO gene and five single-nucleotide polymorphisms(SNPs)in its coding region in the Sanmen breeding population of the razor clam Sinonovacula constricta.The ScFOXO gene encodes a protein of 625 amino...
关键词:Sinonovacula constricta Single-nucleotide polymorphism(SNP) FOXO Growth traits 
Polymorphisms of the IGF1 gene and their association with growth traits, serum concentration and expression rate of IGF1 and IGF1R in buffalo被引量:7
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2017年第12期1064-1074,共11页Mohammed A.EL-MAGD Ayman A.SALEH Abeer A.NAFEAA Shymaa M.EL-KOMY Mohamed A.AFIFI 
Project supported by the Science Technology Development Fund(STDF,No.2585),Ministry of Scientific Research,Egypt
The insulin-like growth factor 1(IGF1) gene is a member of the group of somatotropin axis genes that play a significant role in cell proliferation and growth of muscles. Here, we searched for polymorphisms in buffal...
关键词:Insulin-like growth factor 1 (IGF1) IGFIR Single nucleotide polymorphism (SNP) Growth traits BUFFALO 
Polymorphisms in the Myostatin-1 gene and their association with growth traits in Ancherythroculter nigrocauda
《Chinese Journal of Oceanology and Limnology》2017年第3期597-602,共6页孙艳红 李清 王贵英 祝东梅 陈见 李佩 童金苟 
Supported by the National Science Foundation for Young Scientists of China(No.31402296);the National Science Foundation for Post-Doctoral Scientists of China(No.2014M562077);the Wuhan Chenguang Project for Young Scholars(No.201372304010832)
Myostatin (MSTN) is a member of the transforming growth factor-β gene superfamily that negatively regulates skeletal muscle development and growth. In the present study, partial genomic fragments of Myostatin-1 (M...
关键词:Myostatin-1 (MSTN-1) single nucleotide polymorphisms (SNPs) Ancherythroculter nigrocauda growth traits association analysis 
Vascular Calcification: Current Genetics Underlying This Complex Phenomenon被引量:8
《Chinese Medical Journal》2017年第9期1113-1121,共9页Nonanzit Perez-Hernandez Gad Aptilon-Duque Ruben Blachman-Braun Gilberto Vargas-Alarcon Adrian Asael Rodriguez-Cortes Shely Azrad-Daniez Rosalinda Posadas-Sanchez Jose Manuel Rodriguez-Perez 
Objective: Vascular calcification is the consequence of the complex interaction between genetic, environmental, and vascular factors, which ultimately lead to the deposition of calcium in the tunica intima (atherosc...
关键词:ATHEROSCLEROSIS Cardiovascular Risk GENETICS POLYMORPHISMS Vascular Calcification 
Association between well-characterized lung cancer IncRNA polymorphisms and platinum-based chemotherapy toxicity in Chinese patients with lung cancer被引量:10
《Acta Pharmacologica Sinica》2017年第4期581-590,共10页Wei-jing GONG Jing-bo PENG Ji-ye YIN Xiang-ping LI Wei ZHENG Ling XIAO Li-ming TAN Di XIAO Yi-xin CHEN Xi LI Hong-hao ZHOU Zhao-qian LIU 
This work was supported by the National Key Research and Development Plan (SQ2016YFSF110100 and 2016YFC0905000), National Natural Science Foundation of China (81373490, 81573508, and 81573463), Hunan Provincial Science and Technology Plan of China (2015JC3025), and Open Foundation of Innovative Platform in University of Hunan Province of China (421530004).
Platinum-based chemotherapy is the standard first-line treatment for most lung cancer patients. However, the toxicity induced by platinum-based chemotherapy greatly impedes its clinical use. Previous studies showed ...
关键词:lung cancer platinum-based chemotherapy gastrointestinal toxicity hematological toxicity long non-coding RNA (IncRNA) POLYMORPHISM Chinese patients 
Polymorphisms of clip domain serine proteinase and serine proteinase homolog in the swimming crab Portunus trituberculatus andtheir associationwith Vibrio alginolyticus
《Chinese Journal of Oceanology and Limnology》2017年第2期235-243,共9页刘盟 刘媛 惠敏 宋呈文 崔朝霞 
Supported by the National Natural Science Foundation of China(Nos.41206147,31302187);the Scientific and Technological Innovation Project Financially Supported by Qingdao National Laboratory for Marine Science and Technology(No.2015ASKJ02)
Clip domain serine proteases (cSPs) and their homologs (SPHs) play an important role in various biological processes that are essential components of extracellular signaling cascades, especially in the innate immu...
关键词:Portunus trituberculatus clip domain serine proteinase serine proteinase homolog POLYMORPHISM susceptibility/resistance 
Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes被引量:4
《Acta Pharmacologica Sinica》2017年第1期80-89,共10页Qing LI Ting-ting TANG Feng JIANG Rong ZHANG Miao CHEN Jun YIN Yu-qian BAO Xiang CHENG Cheng HU Wei-ping JIA 
KCNQ1 channel is a member of the voltage-gated potassium channel KQT-like subfamily. The KCNQ1 gene has recently been identified as a susceptibility locus for type 2 diabetes mellitus (T2DM). In the present study, w...
关键词:potassium channel KCNQ1 type 2 diabetes SULFONYLUREAS gliclazide MR PHARMACOGENETICS 
Investigation of Polymorphisms in Coding Region of OsHKT1in Relation to Salinity in Rice
《Rice science》2016年第6期334-338,共5页pham quynh-hoa tran xuan-an nguyen thi-nha-trang tran thi-thuy-anh hoang hai-yen nguyen thi-hong-van tang thi-hanh do thi-phuc 
financially supported by the Vietnam National University,Hanoi,Vietnam(Grant No.QG.14.22)
Rice (Oryza sativa) is sensitive to salinity, but the salt tolerance level differs among cultivars,which might result from natural variations in the genes that are responsible for salt tolerance. High-affinitypotass...
关键词:POLYMORPHISM salt stress OsHKT1 gene RICE 
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